Helatic, biliary, Etc. Flashcards
True or False
Hepatic CYP1A2 expression declines
CYP2D6 and CYP3A4 rises
is a normal physiologic response during pregnancy
True
Generalized pruritus that shows predilection or the palms and soles
Elevated total serum bile acid or transaminase levels
(>10 umol/L)
Intrahepatic Cholestasis of Pregnancy
Assoc with recessive inherited mitochondrial
abnormalities of fatty acid oxidation
Acute Fatty Liver of Pregnancy
Should prompt hospitalization
Nausea, and vomiting
Prolong prothrombin
time
● Low serum albumin
● Hypoglycemia
● High serum bilirubin levels
● CNS symptoms
incubation period that ranges from 40 to 150 days
Hep B
Incub period 15-160 days mean of 7 wks
Hep C
Most common cause of acute hepatitis
Hep E
most common chronic liver isease in the United States
NAFLD
most common chronic liver isease in the United States
NAFLD
most common chronic liver isease in the United States
NAFLD
Usually asymptomatic ● Cause elevated transaminase ● No greater rate of adverse outcome ● Tx: Weight loss, control of DM, and dyslipidemia
Non-alcoholic Fatty Liver Disease (NAFLD)
When other liver disease is excluded, it is the cause of elevated asymptomatic trans- aminase levels in up to 90 percent of cases.
NAFLD
What is the most frequent cause of cirrhosis from chronic alcohol exposure?
Laennec’s cirrhosis
Laennec’s cirrhosis from chronic alcohol exposure is the most frequent cause
What is the cause of cirrhosis in young women post necrosis from Chronic Hep B/C?
Chronic Hep B/C post necrosis
Chronic Hep B/C post necrosis is cause in young women
What is the cause of cryptogenic cirrhosis in NAFLD?
NAFLD
NAFLD cause cryptogenic cirrhosis
