Renal And UT Flashcards
What structural changes occur in the kidneys during pregnancy?
The kidneys become larger, and renal calyces and ureters dilate.
What is a major physiological consequence of intrarenal vasodilation in pregnancy?
Higher effective renal plasma flow and glomerular filtration.
By how much does the glomerular filtration rate (GFR) increase by 12 weeks’ gestation?
20 percent above nonpregnant values.
What serum markers decline substantively during pregnancy?
Serum creatinine and urea.
What is considered an abnormal level of proteinuria in pregnancy?
Proteinuria exceeding 300 mg/dL.
What organism most commonly causes non-obstructive pyelonephritis during pregnancy?
Escherichia coli strains.
What is asymptomatic bacteriuria (ASB) in pregnancy?
Persistent, actively multiplying bacteria within the urinary tract in asymptomatic women.
What bacterial count in urine culture defines ASB?
≥105 colony-forming units/mL.
What percentage of untreated women with ASB develop symptomatic infection?
Approximately 25 percent.
What screening tests are cost-effective for detecting bacteriuria in pregnancy?
Leukocyte esterase and nitrite dipstick tests.
What are the characteristic symptoms of cystitis?
Dysuria, urgency, and frequency.
What is the most common serious non-obstetrical medical complication of pregnancy?
Acute pyelonephritis.
What risk factors increase the likelihood of renal infection in pregnancy?
Nulliparity and young age.
What combination of antimicrobials was 95-percent effective in treating pyelonephritis?
Ampicillin plus gentamicin or cefazolin/ceftriaxone.
What is the recurrence rate of pyelonephritis after initial treatment in pregnancy?
30 to 40 percent.
What type of kidney stones is most common during pregnancy?
Calcium phosphate or hydroxyapatite stones.
What dietary recommendation helps prevent kidney stone recurrence?
Hydration and a diet low in sodium and protein.
What imaging modality is second-line for nephrolithiasis in pregnancy after a non-diagnostic sonogram?
Magnetic Resonance Imaging (MRI).