non-communicable diseases Flashcards
bbc bitesize
1
Q
alcohol
definition
A
A depressant that can be found in wines, spirits and beers. Also known as ethanol.
2
Q
alloy
definition
A
An alloy is a mixture of two or more elements, at least one of which is a metal.
3
Q
alveoli
definition
A
Tiny air sacs in the lungs, where gas is exchanged during breathing.
4
Q
Alzheimer’s disease
definition
A
A disease in which the brain degenerates and short term memory is lost.
5
Q
What are arteries?
A
Blood vessels that carry blood away from the heart.
6
Q
What is blood pressure?
A
The force of blood against the artery walls.
7
Q
What are bronchioles?
A
The many small, branching tubules into which the bronchi subdivide.
8
Q
bronchitis
definition
A
Inflammation of the bronchi and bronchioles.
9
Q
cancer
definition
A
A disease caused by normal cells changing so that they grow and divide in an uncontrolled way. The uncontrolled growth causes a lump called a tumour to form.
10
Q
What is carbon monoxide?
A
Poisonous gas produced during incomplete combustion.
11
Q
What does cardiovascular mean?
A
Relating to the heart and the blood vessels.
12
Q
What is the cervix?
A
Ring of muscle at the lower end of the uterus.
13
Q
chemotherapy
definition
A
The use of chemicals to treat cancer. The chemicals used are highly toxic to cells that divide rapidly.
14
Q
cholesterol
definition
A
A type of lipid (fatty substance).
15
Q
What is cirrhosis?
A
Scarring of the liver, which can be caused by alcoholism or hepatitis.
16
Q
What is a clot?
A
A clump of platelets and blood cells that forms when a blood vessel is damaged.
17
Q
What is COPD?
A
COPD or chronic obstructive pulmonary disease is the name to several lung diseases that restrict air flow in the lungs and cause breathing difficulties for a patient.
18
Q
What does coronary mean?
A
Referring to the heart and the blood vessels which serve the heart tissues.
19
Q
coronary heart disease
definition
A
A form of heart disease in which one or more of the coronary arteries become blocked, depriving the heart muscle of oxygen.
20
Q
correlation
definition
A
A relationship between two sets of data, such that when one set changes you would expect the other set to change as well.
21
Q
diabetes
definition
A
A serious disease in which the body is unable to regulate blood sugar.
22
Q
What is a donor?
A
A person or organism providing an organ or tissue for transplant.
23
Q
element
definition
A
A substance made of one type of atom only.
24
Q
What is emphysema?
A
Disease in which the walls of the alveoli break down, reducing the surface area for gas exchange in the lungs.
25
epidemiology
| definition
The study of the distribution and patterns of health and disease.
26
What is a heart attack?
When the supply of blood to the heart is suddenly blocked.
27
heart disease
| definition
A wide range of conditions that affect the heart.
28
heart faliure
| definition
A condition where the heart is failing to pump sufficient blood around the body at the appropriate pressure.
29
What is a heart transplant?
An operation to replace a damaged heart with a healthy heart from a donor.
30
What is hepatitis?
Inflammation or swelling of the liver, for example because of infection by a virus or drinking too much alcohol.
31
What is a histogram?
A graphical representation of the distribution of numerical data.
32
immune system
| definition
The body's defence system against entry of any foreign body, including pathogens and agents such as pollen grains. The role of the immune system is to prevent disease.
33
immunosuppressant drug
| definition
A type of drug that prevents a patient's immune system from rejecting a transplant.
34
What is insulin?
A hormone that regulates the level of sugar in the blood and can be produced by genetically modified bacteria.
35
ionising radiation
| definition
Radiation that is able to remove electrons from atoms or molecules to produce positively charged particles called ions.
36
lipid
| definition
Fat or oils, composed of fatty acids and glycerol.
37
What is the liver?
The large organ, beside the stomach, which has many functions, including processing substances absorbed by the digestive system and a role in the storage of the body's carbohydrate.
38
monoclonal antibody
| definition
Identical copies of an antibody produced by fusing a spleen cell with a cancerous white blood cell which can be designed to bind to many different substances.
39
mucus
| definition
Slimy white protein, which lines the respiratory tract and alimentary canal.
40
neurological
| meaning
To do with the nervous system.
41
What is nicotine?
The addictive substance found in tobacco and tobacco smoke.
42
non-communicable disease
| definition
A disease that is not transferred between people or other organisms.
43
obesity
| definition
The medical term for being very overweight, owing to the excessive accumulation of body fat.
44
organ
| definition
A group of different tissues that work together to carry out a particular function, eg heart and lungs.
45
oxygen
| definition
Gaseous element making up about 20% of the air, which is needed by living organisms for respiration.
46
palliative care
| definition
Health care that focuses on relieving and preventing suffering, typically near the end of a patient's life when they are terminally ill.
47
qualitative
| definition
Results that are not expressed as numbers or numerical data, eg they can be expressed as present or absent, or as colours.
48
quantitative
| definition
Results that can be expressed using numerical values.
49
radioactive
| definition
When unstable atoms give off particles that can be harmful to humans.
50
radiotherapy
| definition
Using ionising radiation to treat cancer by targeting cancerous cells.
51
regenerate
| definition
To restore something to its original form. For example, a catalyst is regenerated at the end of a reaction. Certain tissues and organs can regenerate themselves by producing new cells.
52
What is a representative sample?
A representative sample is one that accurately represents the whole of the group.
53
reproductive system
| definition
The organs and tissues involved in producing offspring.
54
respiration
| definition
The chemical change that takes place inside living cells, which uses glucose and oxygen to release the energy that organisms need to live. Carbon dioxide is a by-product of respiration.
55
risk factor
| definition
Something that increases a person's chances of developing a disease.
56
stent
| definition
A device, consisting of a wire mesh tube, used to keep a narrowed or blocked coronary artery open.
57
stroke
| definition
Damage to the brain caused by bleeding or blood clots in the brain's blood vessels.
58
tumour
| definition
The lump of cells formed as a result of uncontrolled cell division.
59
virus
| definition
An ultramicroscopic infectious non-cellular organism that can replicate inside the cells of living hosts, with negative consequences.
60
Diseases can be grouped into two types:
- non-communicable
| - Communicable
61
What are non-communicable diseases?
Diseases which are not transferred between people or other organisms
62
What are communicable diseases?
Diseases which can be transferred from one person to another, or from one organism to another, eg in humans, these include measles, food poisoning and malaria.
63
Examples of non-communicable diseases
- cancer
- diabetes
- genetic disorders and conditions
- heart disease
- neurological disorders
64
Interactions between different types of diseases
| overview
Different types of disease may interact. This can mean that the presence of one disease can lead to a higher chance of developing another disease.
65
Interactions between different types of diseases
Defects in the immune system
Defects in the immune system mean that an individual is more likely to suffer from infectious diseases. For instance, human immunodeficiency virus (HIV) infections, which lead to AIDS, affect the immune system and lead to an increase risk of developing other infectious diseases.
66
Interactions between different types of diseases
Viruses
Viruses living in cells can be the trigger for cancers. For instance, the majority of cases of cancer of the cervix are linked with a virus present in the female reproductive system.
67
Interactions between different types of diseases
Reaction of the immune system to pathogens
The reaction of the immune system to pathogens and other foreign bodies can trigger allergic reactions that lead to skin rashes and asthma. For instance, severe respiratory infections in babies can lead to asthma in later childhood.
68
Interactions between different types of diseases
severe physical illness
Severe physical ill health can lead to depression and other types of mental illness.
69
Risk factors
Anything that increases a chance of developing a disease is called a risk factor. Risk factors can be caused by lifestyle factors or substances in a person's body or their environment. Some diseases are caused by an interaction between risk factors.
Some risk factors have been proven to cause a disease. We know that smoking causes lung cancer. Other risk factors are linked but not proven.
70
List a risk factor and effect of Type 2 diabetes
Risk factor: Obesity
| Effect: Blood sugar levels cannot be regulated properly
71
List a risk factor and effect of Liver cirrhosis
Risk factor: Alcohol
| Effect: Scar tissue is formed in the liver which stops it removing toxins
72
List a risk factor and effect of Lung cancer
Risk factor: Smoking
| Effect: Smoking causes lung cancer and also the underdevelopment of unborn babies
73
Causal mechanisms
Correlation
cancer
Research has established links between cancer and various lifestyle factors, chemicals produced in the body, or that enter the human body, and chemicals in the environment. Scientists have established several causal mechanisms for these risk factors.
74
Correlation and cause
If there is a correlation between a particular factor and an outcome, it does not mean that the factor necessarily causes the outcome. Scientists must look for a possible mechanism by which the factor could be the likely cause.
75
Correlation and cause
| lung cancer
In the case of lung cancer, analyses of cigarette smoke have shown that at least 70 of the chemicals present in smoke will cause cancer in laboratory animals which establishes a causal link.
76
Cancers
Cancers are non-communicable diseases. This means they cannot be caught. Instead they develop. Cancers occur when cell division goes wrong. This causes cells to grow out of control, which form a tumour.
77
How are cancers looked for?
Cancers are looked for by doctors in a process called screening. This can be in an x-ray, in blood or urine tests or by using monoclonal antibodies.
78
Causes of cancer
Many cancers are caused by smoking or drinking too much. Others are caused by infections such as the HPV virus. Other causes include the Sun's UV rays and some environmental pollutants. The risk of cancer also increases as we get older.
79
Treatment for cancers include:
- chemotherapy
using chemicals to kill cancerous cells
- radiotherapy
using x-rays to kill cancerous cells
- palliative
this helps a person who has fatal cancer to die as comfortably as possible
80
Smoking increases the risk of cardiovascular disease in several ways:
- Smoking damages the lining of the arteries, including the coronary arteries. The damage encourages the build-up of fatty material in the arteries. This can lead to a heart attack or a stroke.
- Inhalation of carbon monoxide in cigarette smoke reduces the amount of oxygen that can be carried by the blood.
- The nicotine in cigarette smoke increases heart rate, putting strain on the heart.
- Chemicals in cigarette smoke increase the likelihood of the blood clotting, resulting in a heart attack or stroke.
81
A person may develop COPD - chronic obstructive pulmonary disease. This condition includes the diseases chronic bronchitis and emphysema. In COPD:
- smoking damages the bronchioles and can eventually destroy many of the alveoli in the lungs
- the airways become inflamed and mucus, which normally traps particles in the lungs, builds up
- the patient becomes breathless, and finds it more and more difficult to obtain the oxygen required for respiration
82
Negative effects of CPOD
The damage caused by COPD is permanent. The disease cannot be cured, and can result in death. It is essential that the person seeks medical help to try to prevent progression of the disease.
83
Lung cancer
The carcinogens in cigarette smoke also cause lung cancer. Almost all cases of lung cancer are caused by smoking - smaller numbers of cases are linked with air pollution and ionising radiation from radon gas, a radioactiveelement found in the environment in some parts of the country.
84
The liver can regenerate its cells, but long-term alcohol abuse causes serious damage. Give the sequence it occurs in.
1) The patient begins by feeling sick, experiences weight loss and loss of appetite. There is a yellowing of the eyes, confusion, drowsiness and vomiting blood.
2) Alcohol causes lipids to build up in the liver which is called fatty liver disease.
3) Alcohol damage leads to alcoholic hepatitis, which can lead to death.
4) Cirrhosis of the liver can develop - the liver becomes scarred and loses its ability to function.
5) The changes are now irreversible and the reduced ability to process alcohol can also lead to brain damage.
85
Alcohol affects the brain in several ways, it:
- slows reaction time
- causes difficulty walking
- can impair memory
- causes slurred speech
- causes changes in sleep patterns and mood, including increased anxiety and depression.
86
Longer term drinking of excess alcohol:
- causes brain shrinkage
- leads to memory problems
- leads to psychiatric problems
- may result in the patient requiring long-term care.
87
Alcoholism has impacts on social and economic aspects:
- there is increased violence, antisocial behaviour and other crime associated with alcoholism
- there is an increased risk of accidents
- there is increased absence from work
- alcoholism increases the likelihood of relationship break-up
- alcoholism causes mental decline
- alcoholism increases treatment costs to NHS
88
Obesity and cardiovascular disease
Obesity leads to high blood pressure and the build-up of fatty deposits in the arteries, which lead to cardiovascular disease. It also increases the likelihood of developing diabetes, another risk factor cardiovascular disease.
Being obese - with deposits of lipids in the abdomen - increases blood pressure beyond normal levels and increases levels of blood lipids.
89
Obesity and type 2 diabetes
Body fat also affects the body's ability to use insulin.
Type 2 diabetes is where the body's cells lose their sensitivity to insulin – they no longer respond, or respond less effectively, to the insulin that's produced.
Obesity accounts for 80 to 85 per cent of the risk of type 2 diabetes. Rising obesity is linked with 'western diet' - a diet that includes energy-rich 'fast foods' and an inactive lifestyle.
90
How to reduce the risk of developing cardiovascular disease.
The risk of developing cardiovascular disease and type 2 diabetes can be reduced by eating a balanced diet, with unrefined, unprocessed, 'whole foods', and taking regular exercise.
91
BMI calculation
weight (kg) / (height (m))^2
92
Samples must be representative - they must reflect the population under study. They cannot:
- focus on certain groups and ignore others
| - be affected by bias
93
To obtain a representative sample:
- the study must be wide, and cover all groups in the population being studied
- the study must be random within these groups
94
When working with samples of human populations, studies must take account of possible variations owing to differences:
- between the sexes
- resulting from people of different ages taking part
- in people's lifestyles, which could affect the study
95
principles of sampling
| what is a subsection and what is it used?
Analyses can be carried out on sub-sets of data within the whole study, so that comparisons can be made within the same age group, for instance.
96
Principles of sampling
| In scientific models
In scientific studies, it may be difficult to control lifestyle factors that have the potential to affect the study, particularly if the study is long-term. People involved in a long-term study of the effects of alcohol intake, for instance, will have different lifestyle factors, for instance diet and exercise that could potentially affect the results of the study.
97
Bar charts
Bar charts show data collected for separate groups. The height of the bar is proportional to the measured number or frequency.
Note that the bars in a bar chart are all the same width. They do not touch each other as they show distinct categories.
98
Histograms
Histograms look similar to bar charts, but show how the frequently data occur within certain ranges.
The independent variable is therefore continuous and is divided into sub-sections or classes.
The bars of a histogram are next to each other. The area of each bar is proportional to the frequency of each class interval. The bars of a histogram may not be the same width - it depends on the range they cover.
99
Line graphs
Line graphs display data where both variables are continuous.
With line graphs, you have a choice between connecting the plots point-to-point, or using a line of best fit.
Joining dots point to point is essential to show fluctuations in data - for instance, with the death rates - above - or a person's body temperature. We can also connect data point to point when we are confident of their quality.
100
Line of best fit
A line of best fit looks at how variables behave in relation to each other - it is used to establish or display a correlation or a trend. These relationships may not be obvious from a table of data or could be obscured by experimental errors. Lines of best fit are also used to make predictions.
101
Coronary heart disease
Coronary heart disease occurs when a waxy plaque builds up inside the coronary arteries that supply the heart with oxygen. Drugs and surgery can help to control cardiovascular disease.
102
Ways of treating cardiovascular disease
Medication
How do statins work?
Statins are drugs that help to lower cholesterol in the blood. They do this by lowering the production of cholesterol in the liver.
103
Ways of treating cardiovascular disease
Medication
When are statins prescribed?
Statins are prescribed for people with heart disease or who have a high risk of developing it. They need to be taken long-term. Cholesterol levels will rise again if a person stops taking them.
104
Ways of treating cardiovascular disease
Medication
Who are statins not suitable for?
Statins are not suitable for everyone - they should not be prescribed for people with liver disease, or pregnant or breast feeding women.
105
Ways of treating cardiovascular disease
Medication
Side effects of statins
Some patients taking statins often experience side-effects such as headaches and memory loss. There have been reports of statins being linked with type 2 diabetes and liver damage.
106
Ways of treating cardiovascular disease
Surgical procedures
stents
Coronary arteries that are blocked or have become narrow can be stretched open and a stent inserted to restore and maintain blood flow.
They can be used in instances where drugs are less effective, and offer a longer term solution. Stents are made from metal alloys and do not lead to an immune response in the patient.
107
Ways of treating cardiovascular disease
Surgical procedures
stents
Around 75,000 operations are carried out each year. Risk factors depend on the patient's:
- age
- general health
- whether they have had a heart attack
The operation is safe as it does not involve surgery, but there is a risk of bleeding, heart attack or stroke.
108
Ways of treating cardiovascular disease
Surgical procedures
Heart transplants
When is a heart transplant required?
A heart transplant is required in cases of heart failure. Coronary heart disease can lead to heart failure. The heart fails to pump sufficient blood and organs are starved of oxygen. There will be degrees of severity of heart failure.
109
Ways of treating cardiovascular disease
Surgical procedures
Heart transplants
A donor heart is transplanted. In rare cases, a heart is transplanted along with lungs.
A consultant assesses the patient's condition. If other treatments are not managing the heart condition, a transplant may be recommended and a patient will be put on a waiting list. A transplant puts major strain on the body, and the benefits and risks will be evaluated including whether the patient's condition is sufficiently severe and other health factors.
110
Ways of treating cardiovascular disease
Surgical procedures
Heart transplants
artificial hearts
Artificial hearts are plastic devices used occasionally to keep patients alive whilst waiting for a heart transplant. They can also be used to allow a patient's heart to rest to help it recover.
111
Ways of treating cardiovascular disease
Surgical procedures
Heart transplants
After the transplant, the patient will:
- need time to heal, recover and build up strength
- have to take drugs called immunosuppressant drugs for the rest of their life - this prevents the person's immune system from rejecting the donor heart
- have an increased risk of infection because of these drugs
112
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: statins (drugs)
- Reduce the risk of heart attack.
- Studies have shown a decrease in 'bad cholesterol' and an increase in 'good cholesterol'.
- Used to reduce high cholesterol levels that have genetic causes.
- May have beneficial effects on other conditions.
113
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the disadvantages of the treatment: Statins (drugs)
- Not suitable for people with liver disease.
- Some side effects.
- Must be taken for life.
- Should not be taken if pregnant or breastfeeding.
114
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: Heart transplant
improve quality of life
115
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the disadvantages of the treatment: Heart transplant
- Few donor hearts are available.
- Recovery time is long.
- There is a risk of rejection by the body's immune system.
116
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: Stents
Widen coronary arteries that have not responded to drug treatment. The recovery time is short following insertion of the stent.
117
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: Stents
- Widen coronary arteries that have not responded to drug treatment.
- The recovery time is short following insertion of the stent.
118
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: lifestyle changes
These include stopping smoking, reducing alcohol intake, eating a balanced diet and regular exercise. These changes will improve the health of all people; those with and without cardiovascular disease.
119
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the advantages of the treatment: lifestyle changes
These include stopping smoking, reducing alcohol intake, eating a balanced diet and regular exercise.
These changes will improve the health of all people; those with and without cardiovascular disease.
120
Drugs used alongside heart conditions and transplants prolong life.
Evaluation of different treatment methods
List the disadvantages of the treatment: Lifestyle changes
These include stopping smoking, reducing alcohol intake, eating a balanced diet and regular exercise.
These changes will improve the health of all people; those with and without cardiovascular disease.
121
What is the carcinogen in cigarettes?
Tar
122
Which organ in the body can regenerate?
Liver
123
What type of drug is alcohol?
Depressant
124
If, in an investigation of a disease, two sets of data show a correlation, what must a scientist do to establish that it was a change in one variable that led to a change in the other?
To establish that one variable causes a change in another, a possible causal mechanism must be looked for.
