Nomenclature

Question 1

How to indicate substrains?

Answer 1

/

Question 2

Describe the appearance of a lab code and it’s location.

Answer 2

1-5 letters, starting with an uppercase and followed by lowercase. Follows ‘/’. May present in cumulative strings

Question 3

How to list a F1 hybrid

Answer 3

Female ‘x’ Male

Question 4

How to list a RI strain from two inbred parental strains

Answer 4

Female’X’Male - Specific line

Question 5

How to list a mutant gene

Answer 5

Parent gene (italics, starting with uppercase letter), mutant allele in superscript

Question 6

How would a co-isogenic gene look?

Answer 6

Strain/Labcode-Gene(italics), allele(superscript)

Question 7

How to list a transgene

Answer 7

Tg(brief description)#(assigned)Labcode
Example: FVB(MMTV-Erb2)1Led

Question 8

How to list transgene that causes insertional mutation in identified endogenous gene?

Answer 8

Gene (italics), tg1Labcode (superscript)

Question 9

How to list targeted mutation

Answer 9

Gene (italics), tm1Labcode (superscript)

Question 10

How to list gene replacement or knock in

Answer 10

Gene replaced, gene added (superscript)

Question 11

At which generation is backcrossing complete? How is this noted?

Answer 11

N10, noted with a ‘.’ between background and donor strain

Question 12

What occurs after N5 backcrossing?

Answer 12

Incipient congenic, ‘;’ between background an donor strain

Question 13

How is the background strain indicated if of mixed genetic origin?

Answer 13

STOCK

Question 14

How is the donor strain indicated if of mixed origin?

Answer 14

Cg

Question 15

How are outbred stock that meet specific criteria designated?

Answer 15

Labcode:Stock