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Primary Pharm > NMBs > Flashcards

NMBs Flashcards

1
Q

Which NMBs are aminosteroids

A

<30% metabolised
Rocuronium
Vecuronium
Pancuronium

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2
Q

Which NMBs are benzylisoquinoliums

A

> 90% metabolised
Atracurium
Cisatracurium
Mivacurium
Tubocurarine

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3
Q

What is the dose of sux and how quickly does it work

A

1-1.5mg/kg
30secs

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4
Q

How is sux presented

A

solution
50mg/ml

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5
Q

Which NMBs are short acting

A

sux
mivacurium

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6
Q

Which NMBs are medium acting

A

rocuronium
vecuronium
atracurium
cisactracurium

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7
Q

Which NMBs are long acting

A

Pancuronium 45 min

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8
Q

How is sux metabolised

A

Plasma/pseudocholinesterase

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9
Q

What is the dose of rocuronium

A

0.6mg/kg- 1.2mg/kg
60-120s

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10
Q

What is the presentation of rocuronium

A

colourless solution
50mg/ml

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11
Q

How is rocuronium metabolised

A

Mainly unchanged in bile

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12
Q

What is the dose of vecuronium

A

0.1mg/kg
90-120s

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13
Q

How is vecuronium presented

A

10mg freeze dried powder

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14
Q

How is vecuronium metabolised

A

Liver

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15
Q

What is the dose of pancuronium

A

0.1mg/kg
90-150s

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16
Q

How is pancuronium presented

A

solution 2mg/ml

17
Q

What is the dose of atracurium

A

0.5mg/kg
90-120s

18
Q

How is atracurium presented

A

solution 10mg/ml

19
Q

How is atracurium metabolised

A

ester hydrolysis and hoffman elimination

20
Q

What is the dose of cisatracurium

A

0.2mg/kg
slower onset

21
Q

How is cisatracurium presented

A

solution
2 or 5mg/ml

22
Q

How is cisatracurium metabolised

A

hoffmann elimination to laudanosine

23
Q

What is the dose of mivacurium

A

0.2mg/kg

24
Q

How is mivacurium presented

A

acidic
2mg/ml

25
Q

How is mivacurium metabolised

A

plasma/pseudochilenterase

26
Q

What is the TOF

A

Four stimuli at 2Hz (every 0.5s)

27
Q

What is double burst stimulation

A

Three shocks at 50Hz followed by another three 750ms later
Easier to assess fade

28
Q

What is post tetanic count

A

Tetanic stim of 50Hz for 5 secs then waits 3s then pulse at 1Hz
Number of twitches seen is inversely propotional to degree of blockade

Primary Pharm (4 decks)

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