NMBs Flashcards

1
Q

Which NMBs are aminosteroids

A

<30% metabolised
Rocuronium
Vecuronium
Pancuronium

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2
Q

Which NMBs are benzylisoquinoliums

A

> 90% metabolised
Atracurium
Cisatracurium
Mivacurium
Tubocurarine

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3
Q

What is the dose of sux and how quickly does it work

A

1-1.5mg/kg
30secs

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4
Q

How is sux presented

A

solution
50mg/ml

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5
Q

Which NMBs are short acting

A

sux
mivacurium

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6
Q

Which NMBs are medium acting

A

rocuronium
vecuronium
atracurium
cisactracurium

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7
Q

Which NMBs are long acting

A

Pancuronium 45 min

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8
Q

How is sux metabolised

A

Plasma/pseudocholinesterase

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9
Q

What is the dose of rocuronium

A

0.6mg/kg- 1.2mg/kg
60-120s

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10
Q

What is the presentation of rocuronium

A

colourless solution
50mg/ml

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11
Q

How is rocuronium metabolised

A

Mainly unchanged in bile

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12
Q

What is the dose of vecuronium

A

0.1mg/kg
90-120s

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13
Q

How is vecuronium presented

A

10mg freeze dried powder

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14
Q

How is vecuronium metabolised

A

Liver

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15
Q

What is the dose of pancuronium

A

0.1mg/kg
90-150s

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16
Q

How is pancuronium presented

A

solution 2mg/ml

17
Q

What is the dose of atracurium

A

0.5mg/kg
90-120s

18
Q

How is atracurium presented

A

solution 10mg/ml

19
Q

How is atracurium metabolised

A

ester hydrolysis and hoffman elimination

20
Q

What is the dose of cisatracurium

A

0.2mg/kg
slower onset

21
Q

How is cisatracurium presented

A

solution
2 or 5mg/ml

22
Q

How is cisatracurium metabolised

A

hoffmann elimination to laudanosine

23
Q

What is the dose of mivacurium

24
Q

How is mivacurium presented

A

acidic
2mg/ml

25
How is mivacurium metabolised
plasma/pseudochilenterase
26
What is the TOF
Four stimuli at 2Hz (every 0.5s)
27
What is double burst stimulation
Three shocks at 50Hz followed by another three 750ms later Easier to assess fade
28
What is post tetanic count
Tetanic stim of 50Hz for 5 secs then waits 3s then pulse at 1Hz Number of twitches seen is inversely propotional to degree of blockade