NMBD (ch. 11) Flashcards

1
Q
Succinylcholine (Diacetylcholine or Suxamethonium)
type of NMB
onset
duration
effects
contraindication
A
depolarizing
onset: 30-60sec
duration: 5-10min
never infuse, single-dose bolus
fasiculations, increase potassium by 0.5 mEq/L, MH, increase ICP, histamine release
burn, tbi, hyperkalemia, AKI
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2
Q
Pancuronium (longest acting)
type of NMB
onset
duration
elimination
effects
A
non-depo
onset: 1-2min
duration: 60-75min
liver, renal (renal failure = prolong effect)
CVS: HTN, tachycardia
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3
Q
Rocuronium (intermediate)
type of NMB
onset
duration
elimination
effects
A
non-depo
onset: 2-4min
duration: 30-40min
elimination: kidneys
no CVS effects
prolonged in elderly
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4
Q
Cisatracurium
type of NMB
onset
duration
metabolism
effects
A

non-depo

onset: 2min
duration: 20-35min
metabolism: Hoffman elimination in plasma
effects: no histamine, no CVS

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5
Q
Mivacurium
type of NMB
onset
duration
metabolism
elimination
effects
A
non-depo
onset: 2-3min
duration 20-30min
metabolism: pseudocholinisterase
elimination: kidney
histamine release
minimal CVS effects
CANNOT use neostigmine
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