Nitrate W9 Flashcards

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1
Q

What is nitrate?

A

Dietary nitrate (NO3-)

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2
Q

What does the ingestion of NO3- lead to?

A

Enhanced nitric oxide (NO) bioavailability

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3
Q

What are high-nitrate containing foods?

A

Leafy greens
Root vegetables

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4
Q

How much of nitrate dietary intake does vegetables provide?

A

80%

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5
Q

What is the average dietary intake of nitrate?

A

1-2mmol/d
60-120mg/d

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6
Q

What does NO play an important role in?

A

The modulation of skeletal muscle function

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7
Q

How does ingestion of dietary NO3- enhance NO bioavailability?

A

Via the NO3-nitrite-NO pathway

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8
Q

How is the reaction of the NO3–nitrate-NO pathway catalysed?

A

Bacteria in the mouth
Digestive system

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9
Q

What are the effects of increased NO bioavailability?

A

Increased blood flow to muscle

Increased function of type II fibres

Increased efficiency of mitochondrial respiration

Increased muscle contractile function

increased immune health

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10
Q

How does nitrate effect exercise economy?

A

Lower O2 cost of exercise

Reduced ATP cost of muscle force production

More efficient mitochondrial oxidative phosphorylation

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11
Q

What is exercise economy?

A

O2 cost of exercise

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12
Q

When may chronic supplementation be useful?

A

For highly trained athletes, where performance gains seem harder to achieve

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13
Q

What is an acute dose of nitrate?

A

(5-9mmol)
310-560mg nitrate

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14
Q

When do you use an acute dose of nitrate?

A

2-3hr pre-exercise

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15
Q

When do you use a chronic supplementation of nitrate?

A

3-15 days pre event

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16
Q

What is a chronic supplementation of nitrate?

A

310-560mg nitrate per day

310-560mg nitrate pre-event

17
Q

When consuming beetroot juice, what may interfere with its benefit?

A

Mouthwash
Chewing gum

18
Q

What are the variables of a Beet IT sport shot (70ml)

A

Concentrated beetroot juice (98%)

400mg natural nitrate

7x more concentrated than beetroot juice

Convenient, reliable form

Batch tested

19
Q

What are the variables of other beetroot products?

A

Lower nitrate

Unspecified nitrate content

Organic vegetable products lower in nitrate

Check other ingredients and batch-testing status

20
Q

What food are equal to 400mg nitrate?

A

Beetroot
Bok choy
Rocket lettuce
Parsley
Silver beet spinach
Baby spinach
Celery
Fresh beetroot juice

21
Q

How can nitrate enhance exercise capacity in performance?

A

By reducing the cost of exercise

22
Q

When should you use nitrate?

A

Prolonged submaximal exercise lasting 4-30min

Aerobic fitness

High-intensity intermittent events with short duration and sprint efforts in individual and team sports

During exposure to hypoxic conditions

23
Q

What is the individual variability of nitrate?

A

Lack of evidence on females

Training status influences benefits, with highly-trained endurance athletes not benefiting significantly

23
Q

What are the concerns and safety of beetroot juice?

A

In concentrated form, can cause mild gut discomfort

Can cause a temporary pink colour to urine and stools

Nitrite or nitrite salt are toxic and may be mistaken

Chronic use has not been studied so long-term effects are unknown

Contamination

24
Q

What are the mechanisms of nitrate?

A

Increasing skeletal muscle 02 delivery

Reduced o2 cost of mitochondrial ATP resynthesis

Reduced ATP cost of cross-bridge formation