Nitrate W9 Flashcards
What is nitrate?
Dietary nitrate (NO3-)
What does the ingestion of NO3- lead to?
Enhanced nitric oxide (NO) bioavailability
What are high-nitrate containing foods?
Leafy greens
Root vegetables
How much of nitrate dietary intake does vegetables provide?
80%
What is the average dietary intake of nitrate?
1-2mmol/d
60-120mg/d
What does NO play an important role in?
The modulation of skeletal muscle function
How does ingestion of dietary NO3- enhance NO bioavailability?
Via the NO3-nitrite-NO pathway
How is the reaction of the NO3–nitrate-NO pathway catalysed?
Bacteria in the mouth
Digestive system
What are the effects of increased NO bioavailability?
Increased blood flow to muscle
Increased function of type II fibres
Increased efficiency of mitochondrial respiration
Increased muscle contractile function
increased immune health
How does nitrate effect exercise economy?
Lower O2 cost of exercise
Reduced ATP cost of muscle force production
More efficient mitochondrial oxidative phosphorylation
What is exercise economy?
O2 cost of exercise
When may chronic supplementation be useful?
For highly trained athletes, where performance gains seem harder to achieve
What is an acute dose of nitrate?
(5-9mmol)
310-560mg nitrate
When do you use an acute dose of nitrate?
2-3hr pre-exercise
When do you use a chronic supplementation of nitrate?
3-15 days pre event