Nicotinic Acetylcholine Receptor

Question 1

Cite two physiochemical properties of neonicotinoids

Answer 1

• Moderately water soluble
• Non-ionized

Question 2

two neonicotinoid analogs?

Answer 2

• Clothianidin
• Thiamethoxam

Question 3

Compared to spinosad, what are three important properties of spinetoram?

Answer 3

1. Longer residual control
2. Greater activity
3. Broader pest spectrum

Question 4

Cite 4 features of nicotine:

Answer 4

1. It has a high mammalian toxicity
2. It has a narrow insecticidal spectrum
3. Its use is widespread
4. It is metabolized and excreted slowly in insects

Question 5

What effect do cartap and bensultap have on insects?

Answer 5

Discontinuation of feeding.

Question 6

Briefly explain why stereochemistry is important in pyrethroids.

Answer 6

The enzymatic detoxification of
pyrethroids is dependent at some level on the stereochemistry of the molecule. Thus, different isomers of a molecule may play different roles in the enzymatic detoxification of pyrethroids.