GABA Receptor/Sodium Channel Flashcards

1
Q

Which symptoms usually follow the general pattern of nerve poisoning?

A
  • Restlessness
  • Hyperexcitability
  • Tremors and convulsions
  • Paralysis
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2
Q

What insecticides affect the GABA-gated chloride channel?

A
  • Phenylpyrazoles
  • HCH
  • Cyclodienes
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3
Q

What type of insecticide is Indoxacarb?

A

Oxadiazine

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4
Q

What are two advantages of the physiochemical properties of synthetic pyrethroids?

A
  • Their stereochemistry allows for the synthesis of many different compounds
  • They are highly lipophilic and stay on plant surfaces which minimizes systemic movement
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5
Q

Which was the first photostable pyrethroid?

A

Permetrin

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6
Q

What is the mode of action of Indoxacarb?

A

Blocks sodium ions from flowing into the axon

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