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Year 4 Antibiotics > Niche shit I can never remember > Flashcards

Niche shit I can never remember Flashcards

1
Q

Treatment of cervical cancer - Stage 1A1?

A

Cone biopsy
Radical trachelectomy/Cervicectomy
Hysterectomy

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2
Q

Treatment of cervical cancer - Stage 1A2 & 1B1?

A

TAH +/- Lymphadenectomy

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3
Q

Treatment of cervical cancer - Stage 1B2 & 2A?

A

TAH +/- chemoradiation

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4
Q

Treatment of cervical cancer - Stage 2B and above?

A

Chemoradiotherapy (external/brachy)

4B - palliative radiotherapy

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5
Q

Treatment of endocervical cancer - Stage 1?

A

TAH- BSO

Adjuvant radiotherapy

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6
Q

Treatment of endocervical cancer - Stage 2?

A

TAH-BSO +/- lymphadenectomy
2B - Possible Radical (Werheims)
Adjuvant radiotheraphy

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7
Q

Treatment of endocervical cancer - Stage 3/4?

A

Maximal debulking surgery

Palliative radiotherapy + progesterone

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8
Q

Treatment of ovarian cancer - local?

A

TAH-BSO + adjuvant chemo (unless 1A/1B)

If young - omenectomy, peritoneal washings, lymphadenectomy

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9
Q

Treatment of ovarian cancer - stage 3/4?

A

TAH-BSO + neoadjuvant chemo

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10
Q

Treatment of vulval cancer - localised?

A

Triple incision surgery (WLE, ipsilateral and contralateral lymphadenectomy)
If <1mm deep and <2mm long - WLE

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11
Q

Treatment of vulval cancer if advanced?

A

Radical vulvectomy + neo-adjuvant chemoradiotherapy

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12
Q

Test results in Downs combined test?

A

Low PAPP-A

Increased B-hCG & nuchal translucency

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13
Q

Test rests in Downs - quadruple test?

A

Low AFP, oestriol

High B-hCG & inhibin A

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14
Q

Physiological changes in pregnancy - CO & SV?

A

Increases

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15
Q

Physiological changes in pregnancy - HR?

A

Increases

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16
Q

Physiological changes in pregnancy - BP?

A

Drops and then rises to pre-pregnancy values over pregnancy

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17
Q

Physiological changes in pregnancy - blood volume?

A

Increases

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18
Q

Physiological changes in pregnancy - LFTs?

A

Normal

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19
Q

Physiological changes in pregnancy - bilirubin?

A

Decreases

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20
Q

Physiological changes in pregnancy - GFR?

A

Increases

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21
Q

Physiological changes in pregnancy - WCC?

A

Increases

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22
Q

Physiological changes in pregnancy - Hb?

A

Decreases

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23
Q

Anaemia levels in pregnancy - 1st trimester, 2nd & 3rd trimester and Postpartum?

A

1st - <110
2&3 - <105
Post-partum - <100

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24
Q

Dose of routine Anti-D and when?

A

500IU at 28 and 34 weeks

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25
Q

Dose of Anti-D <12w?

A

250IU if ectopic/TOP/heavy bleeding - no Kleihauer

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26
Q

Dose of Anti-D if >20w and sensitised?

A

500IU - Kleihauer test

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27
Q

Dose of Anti-D postnatally?

A

500IU <72h post-partum

28
Q

Drug management of acute dystonic reaction?

A

Procyclidine

29
Q

Drug management of tardive dyskinesia?

A

Tetrabenazine

30
Q

When do symptoms of alcohol withdrawal come on?

31
Q

When do seizures of alcohol withdrawal come on?

32
Q

When do DTs of alcohol withdrawal come on?

33
Q

Indications for EFM - CTG? 7,1,7

A

Maternal - Previous CS, PET, >42w, PROM>24h, Induced, Heart/DM, APH

Intrapartum - Epidural

Foetal - IUGR, Premature, Multiple pregnancies, Oligohydramnios, Meconium stained liquor, breech, abnormal deoppler

34
Q

Drugs to avoid in breastfeeding?

A 
Aspirin
Amiodarone
Benzodiazepines
Ciprofloxacin
Carbimazole
Lithium
Methotrexate
Sulphonamides
Trimethoprim
Tetracyclines
35
Q

Risk factors for cervical cancer?

A 
HPV acquisition (lots of sexual partners, early age of first sex, no condom use)
Multiparous
COCP
HIV
FHx
Smoking
36
Q

Risk factors for endometrial cancer?

A 
Nulliparous
Late menopause
Obesity
HNPCC
PCOS
DM
Tamoxifen
37
Q

Risk factors for ovarian cancer?

A 
Age
FHx
BRCA1/2
Nulliparity/Early menarche/Late menarche/IVF
Endometriosis 
Smoking
Obesity
38
Q

Reduced risk of ovarian cancers?

A

COCP
Multiparity
Early menopause
Breastfeeding

39
Q

VTE risk assessment - score of 4?

A

Previous VTE
OHSS
APS
Antithrombin 3 deficiency

40
Q

VTE risk assessment - score of 3?

A

Previous provoked VTE
Co-morbidity (Cancer, SLE, SCD, IBD, HF)
Hyperemesis gravidarum
Surgical procedure

41
Q

VTE risk assessment - score of 2?

A

C-Section in labour

BMI >40

42
Q

VTE risk assessment - score of 1?

A 
Thrombophilia
Dehydration
Parity 3 or more
Smoking
Age >35
Multiple pregnancy
FHx of VTE (1st degree)
Immobility
BMI >30
Varicose veins
IVF
Pre-eclampsia
43
Q

Criteria for VTE in pregnancy?

A

4 or more - LMWH from 1st trimester
3 - LMWH from 28w
2 or more postnatally - LMWH for 10d
Admission - LMWH

All given 6w postpartum

44
Q

Aspirin in pregnancy - high RF?

A 
Hx of PET
DM
Chronic hypertension
Renal disease
Multiple pregnancy
SLE/APS
45
Q

Aspirin in pregnancy - moderate RF?

A

BMI>30
Age >35
FHx of PET
Nulliparous

46
Q

When to give aspirin in pregnancy?

A

1 high RF or 2 or more moderate RF

Give 75mg from 12 weeks

47
Q

What personality disorders are in cluster A?

A

Weird, odd

Paranoid
Schizoid
Schizotypal

48
Q

What personality disorders are in cluster B?

A

Wild, dramatic

Antisocial
Borderline
Histrionic
Narcissistic

49
Q

What personality disorders are in cluster C?

A

Worried, anxiety

Avoidant
Dependent
Obsessive/Compulsive

50
Q

Describe paranoid personality disorder?

A

Irrational suspicion and mistrust of others
Interpret motivations as malevolent
Accusatory without evidence
Pathologically jealous

51
Q

Describe schizoid personality disorder?

A

Prefer to be on own, detached from social relationships
Restricted emotional expression
Voluntary social withdrawal

52
Q

Describe schizotypal personality disorder?

A

Odd, eccentric thoughts & behaviours - distorted cognition
Magical thinking, peculiar appearance
Uncomfortable interacting socially

53
Q

Describe antisocial personality disorder?

A

Disregard for rights of others, lack empathy
Manipulative
Impulsive, break rules, often criminal
Conduct disorder predisposes to antisocial

54
Q

Describe borderline personality disorder?

A

Abrupt mood swings, unstable relationships/self-image/indentity
Often self-harm/impulsive
Abuse in childhood

55
Q

Describe histrionic personality disorder?

A

Attention-seeking, excessive emotions, provocative, flamboyant
Sexually inappropriate
Cannot form meaningful relationships

56
Q

Describe narcissistic personality disorder?

A

Grandiosity, superiority, inflated ego, entitled

Lack of empathy, exploit others, criticise others

57
Q

Describe avoidant personality disorder?

A

Social inhibition and inadequacy
Fear of rejection, sensitive to negative evaluation
Desire relationships

58
Q

Describe dependent personality disorder?

A

Need to be cared for by others
Poor confidence, others make decisions for them
Fear being alone

59
Q

Describe obsessive/compulsive personality disorder?

A

Rigid conformity to rules, perfectionist, control
Excludes leisurely activities and friendships
Accepts their thoughts (unlike OCD)

60
Q

Features of Turners (XO)?

A 
Short
Wide nipples
Bicuspid aortic valve
Coarctation of aorta
1o amenorrhoea
61
Q

Features of Noonans syndrome?

A

Webbed neck

Subpulmonary stenosis

62
Q

Features of Williams syndrome?

A 
Elf like features
Aortic stenosis
Hypercalcaemia
Cocktail party
Low tone
63
Q

Features of Patau syndrome?

A

Microcephaly

Polydactyly

64
Q

Features of edwards syndrome?

A

Rockerbottom feet
Microcephaly
Small jaw, cleft palate

65
Q

Features of FXS?

A

Macrocephaly
Big forehead, jaw, ears, testicles
ASD
MV prolapse

66
Q

Features of foetal alcohol syndrome?

A 
Small head
Smooth philtrum
Thin upper lip
Small palpebral fissure
Cerebellar hypoplasia
67
Q

Features of DiGeorge syndrome?

A 
CATCH22
Cardiac abnormalities
Abnormal facies
Thymus deficiency
Cleft palate
Hypothyroidism

Year 4 Antibiotics (9 decks)

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