CCC cancer managements

Question 1

Treatment of localised breast cancer?

Answer 1

Surgery - WLE/Mastectomy +/- Sentinel Biopsy
Adjuvant Chemotherapy
Adjuvant Radiotherapy
Hormonal (Trastuzamab (Her2 + for 12m), Tamoxifen (ER/PR+ for 5y), Anastrazole (better in post-menopause))

Question 2

Treatment of advanced breast cancer?

Answer 2

Palliative Radio - control symptoms
Palliative chemo - palliate symptoms
Palliative hormonal - ER/PR + - Tamoxifen/Anastrazole

Question 3

Worst prognosis in breast cancer?

Answer 3

ER-
PR-
Her2 +

Question 4

Paraneoplastic syndromes in lung cancer?

Answer 4

SCLC

• SiADH - low Na
• ACTH - Cushings
• PTH - hypercalcaemia
• LEMS
• hCG - gynaecomastia

NSCLC
- PrTH - hypercalcaemia

Question 5

Treatment of limited SCLC?

Answer 5

Radical radiotherapy - SABR

Question 6

Treatment of metastatic SCLC?

Answer 6

Palliative chemo

Palliative radio - primary tumour, palliative symptoms and prophylactic cranial

Question 7

Treatment of stage 1/2 NSCLC?

Answer 7

Surgical excision (lobectomy)
Adjuvant chemoradiotherapy

Question 8

Treatment of stage 2/3 NSCLC?

Answer 8

Concurrent chemoradiotherapy

Question 9

Treatment of palliative NSCLC?

Answer 9

Palliative chemoradiotherapy

Question 10

Treatment of Localised prostate cancer?

Answer 10

T2 or less

Radical prostatectomy
Adjuvant radiotherapy (external beam/brachy)
Adjuvant hormonal (LHRH agonists (leuprorelin), GnRH antogonists (degarelix))

Question 11

Treatment of metastatic prostate cancer?

Answer 11

Palliative surgery and radiotherapy

Question 12

Treatment of Stage A/B/C colorectal cancer?

Answer 12

Radical resection
Neoadjuvant/Adjuvant radio (+chemo in Stage C)
Anti-angio/VEGF

Question 13

Treatment of Stage D colorectal cancer?

Answer 13

Palliative surgery and radiotherapy