NICE Guidelines for Pharmacological Treatment

Question 1

First line in schizophrenia.

Answer 1

Atypical antipsychotics

Question 2

Second line in schizophrenia

Answer 2

Typical antipsychotics

Question 3

For treatment resistant schizophrenia.

Answer 3

Clozapine

Question 4

First line in bipolar mania.

Answer 4

Trial antipsychotic such as olanzapine

Question 5

First line in bipolar depression.

Answer 5

Olanzapine with or without fluoxetine

Question 6

First line in bipolar maintenance.

Answer 6

Lithium

Question 7

Second line in bipolar maintenance.

Answer 7

Sodium valproate

Question 8

Last line in bipolar depression.

Answer 8

Lamotrigine

Question 9

First line in early Parkinson’s.

Answer 9

L-dopa and DDi

Question 10

Second line in early Parkinson’s.

Answer 10

Dopamine agonist

Question 11

Option in advanced Parkinson’s with optimal oral treatment.

Answer 11

SC apomorphine

Question 12

First line in tremor with Parkinson’s.

Answer 12

Anticholinergics

Question 13

Add in for Parkinson’s with dyskinesia or motor fluctuation.

Answer 13

COMT inhibitor

Question 14

Preferred in mild Parkinson’s or late stage add in.

Answer 14

MAO-B inhibitor

Question 15

Add in for dyskinesias in late stage Parkinson’s.

Answer 15

Amantadine

Question 16

First line in cognitive symptoms of dementia.

Answer 16

AChE inhibitor

Question 17

First line alternative in dementia.

Answer 17

Memantine

Question 18

Licensed antipsychotic for BPSD.

Answer 18

Risperidone

Question 19

First line in GAD.

Answer 19

SSRI

Question 20

Second line in GAD.

Answer 20

Alternative SSRI or SNRI

Question 21

Third line in GAD.

Answer 21

Pregabalin

Question 22

First line in panic disorder.

Answer 22

SSRI

Question 23

Second line in panic disorder.

Answer 23

Imipramine

Question 24

First line in social anxiety disorder.

Answer 24

SSRI

Question 25

Second line in social anxiety disorder.

Answer 25

Alternative SSRI or SNRI

Question 26

Third line in social anxiety disorder.

Answer 26

MAOI

Question 27

Licensed for short term use in GAD crisis.

Answer 27

Diazepam

Question 28

Licensed for physical anxiety symptoms.

Answer 28

Propranolol

Question 29

First line in sulphonylurea overdose.

Answer 29

IV dextrose

Question 30

First line in beta-blocker overdose.

Answer 30

Fluid and atropine

Question 31

Second line in beta-blocker overdose.

Answer 31

IV glucagon infusion over 5-10 minutes

Question 32

First line in CCB overdose.

Answer 32

Fluid resus followed by calcium salts

Question 33

Second line in CCB overdose.

Answer 33

High dose insulin-dextrose infusion

Question 34

First line in toxic alcohol overdose.

Answer 34

Ethanol (preferred substrate)

Question 35

Second line in toxic alcohol overdose.

Answer 35

Fomepizole

Question 36

Adjunct in cyanide poisoning.

Answer 36

Sodium thiosulphate

Question 37

Treatment in severe cyanide poisoning.

Answer 37

Dicobalt edetate

Question 38

Unlicensed treatment for cyanide poisoning.

Answer 38

Hydroxycobalamin

Question 39

First line in pre-hospital first aid of cyanide poisoning.

Answer 39

Amylnitrite

Question 40

First line cyanide poisoning. IMMEDIATE

Answer 40

Oxygen to reverse metabolic acidosis

Question 41

First line in BZD only overdose.

Answer 41

Flumazenil

Question 42

First line in opioid overdose.

Answer 42

Naloxone

Question 43

First line in paracetamol overdose.

Answer 43

N-acetylcysteine

Question 44

Indication for charcoal haemoperfusion.

Answer 44

Theophylline or carbamazepine overdose

Question 45

Indication for urinary alkalisation.

Answer 45

Overdose of aspirin

Question 46

First line BZD in status epilepticus.

Answer 46

IV lorazepam

Question 47

Buccal BZD alternative in status epilepticus.

Answer 47

Midazolam

Question 48

Rectal BZD alternative in status epilepticus.

Answer 48

Diazepam

Question 49

First line AED in status epilepticus.

Answer 49

Phenytoin

Question 50

Last line in status epilepticus.

Answer 50

Induction of coma

Question 51

First line in partial seizures.

Answer 51

Carbamazepine

Question 52

Second line in partial seizures.

Answer 52

Sodium valproate | Lamotrigine

Question 53

First line in generalised tonic-clonic seizures.

Answer 53

Sodium valproate | Lamotrigine

Question 54

Second line in generalised tonic-clonic seizures.

Answer 54

Carbamazepine | Topiramate

Question 55

First line in absence seizures.

Answer 55

Sodium valproate

Question 56

Second line in absence seizures.

Answer 56

Lamotrigine | Ethosuximide

Question 57

Contraindicated in MAT seizures.

Answer 57

Carbamazepine

Question 58

First line in epilepsy in pregnancy.

Answer 58

Lamotrigine

Question 59

First line in Dravets syndrome.

Answer 59

Sodium valproate

Question 60

Second line in Dravets syndrome.

Answer 60

Sodium valproate | And clobozam

Question 61

Third line in Dravets syndrome.

Answer 61

Sodium valproate And clobozam And stiripentol

Question 62

First line in Lennox-Gastaut syndrome.

Answer 62

Sodium valproate

Question 63

Second line in Lennox-Gastaut syndrome.

Answer 63

Lamotrigine Clobozam Topiramate Phenytoin