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Pharm + Patient Year 3 Sem 2 > Drug Actions > Flashcards

Drug Actions Flashcards

1
Q

What is the drug class and action of olanzapine?

A

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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2
Q

What is the drug class and action of risperidone?

A

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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3
Q

What is the drug class and action of zuclopenthixol?

A

Typical antipsychotic

Post-synaptic dopamine receptor blocker

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4
Q

What is the drug class and action of clozapine?

A

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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5
Q

What is the drug class and action of aripiprazole?

A

Partial agonist at D2 receptors, reducing but not blocking activity

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6
Q

What is the drug class and action of quetiapine?

A

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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7
Q

What is the drug class and action of haloperidol?

A

Typical antipsychotic

Post-synaptic dopamine receptor blocker

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8
Q

What is the drug class and action of chlorpromazine?

A

Typical antipsychotic

Dopamine D2 receptor inhibitor

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9
Q

What is the drug class and action of donepezil?

A

AChE inhibitor

Increase amount of acetylcholine present in the synapse

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10
Q

What is the drug class and action of rivastigmine?

A

AChE inhibitor

Increase amount of acetylcholine present in the synapse

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11
Q

What is the drug class and action of ropinirole?

A

Non-ergot dopamine agonist

Agonists at post-synaptic dopamine receptors

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12
Q

What is the drug class and action of pramipexole?

A

Non-ergot dopamine agonist

Agonists at post-synaptic dopamine receptors

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13
Q

What is the drug class and action of levodopa?

A

Dopamine precursor

Increasing dopamine available in presynaptic neurones

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14
Q

What is the drug class and action of entacapone?

A

COMT inhibitor

Prevents metabolism of levodopa to 3-O-methyldopa

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15
Q

What is the drug class and action of pergolide?

A

Ergot dopamine agonist

Agonist at post-synaptic dopamine receptors

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16
Q

What is the drug class and action of rasagiline?

A

MAO-B inhibitor

Prevent metabolism of dopamine, increasing dopamine available at receptors

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17
Q

What is the drug class and action of carbidopa?

A

DD inhibitor

Prevent peripheral metabolism of levodopa

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18
Q

What is the drug class and action of sertraline?

A

SSRI

Boost serotonin by blocking reuptake

19
Q

What is the drug class and action of citalopram?

A

SSRI

Boost serotonin by blocking reuptake

20
Q

What is the drug class and action of fluoxetine?

A

SSRI

Boost serotonin by blocking reuptake

21
Q

What is the drug class and action of mirtazapine?

A

NaSSA

Antagonist of adrenergic, 5-HT2A, 5-HT2C and H1 receptors

22
Q

What is the drug class and action of venlafaxine?

A

SNRI

Boost serotonin and noradrenaline by blocking reuptake

23
Q

What is the drug class and action of amitriptyline?

A

TCA

Boost serotonin and noradrenaline by blocking reuptake

24
Q

What is the drug class and action of isocarboxazid?

A

MAOI

Stop breakdown of serotonin and noradrenaline

25
Q

What is the drug class and action of phenelzine?

A

MAOI

Stop breakdown of serotonin and noradrenaline

26
Q

What is the drug class and action of duloxetine?

A

SNRI

Boost serotonin and noradrenaline by blocking reuptake

27
Q

What is the drug class and action of dosulepin?

A

TCA

Boost serotonin and noradrenaline by blocking reuptake

28
Q

What is the drug class and action of amisulpride?

A

Typical antipsychotic

Dopamine D2 receptor inhibitor

29
Q

What is the drug class pregabalin?

A

Anti-epileptic

30
Q

What is the drug class and action of aspirin?

A

NSAID

Irreversible inhibitor of COX-1 and COX-2, Prostaglandin production reduced

31
Q

What is the drug class and action of ibuprofen?

A

NSAID

Reversible inhibitor of COX-1 and COX-2, Prostaglandin production reduced

32
Q

What is the drug class and action of paracetamol?

A

Antipyretic

Paracetamol inhibits COX-3 and (weakly) COX-2, Prostaglandin production reduced

33
Q

What is the drug class and action of morphine?

A

Opioid

Agonist at opioid receptor, preventing GABA, thus allowing descending pathway to work with MOP

34
Q

What is the drug class and action of ondansetron?

A

5-HT3 antagonist

Inhibits serotonin in CTZ and GI tract

35
Q

What is the drug class and action of aprepitant?

A

NK1 antagonist

Inhibits substance P in CTZ

36
Q

What is the drug class and action of metoclopramide?

A

D2 antagonist

Inhibits dopamine in the CTZ

37
Q

What is the drug class and action of domperidone?

A

D2 antagonists

Inhibits dopamine in the CTZ

38
Q

What is the drug class and action of hyoscine?

A

Anticholinergic

Inhibits ACh primarly present in vestibular centre and GI tract

39
Q

What is the drug class and action of cyclizine?

A

Anticholinergic

Inhibits ACh primarly present in vestibular centre and GI tract

40
Q

What is the drug class and action of promethazine?

A 
Antihistamine
Inhibits histamine (primarly) present in vestibular centre and GI tract
41
Q

What is the drug class and action of zopiclone?

A

Z drug

Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors

42
Q

What is the drug class and action of diazepam?

A

BZD

Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors

43
Q

What is the drug class and action of memantine?

A

NMDA receptor antagonist

Dampens glutamate firing thus having a neuroprotective factor

44
Q

What is the drug class and action of thiopental?

A

Barbiturate

Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors

Pharm + Patient Year 3 Sem 2 (29 decks)

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