Newborn Infections

Question 1

Toxo:

triad

Answer 1

Chorioretinitis
hydrocephalus
diffuse intracranial calcification

Question 2

Rubella:

4 sxs

Answer 2

PDA
Cataracts
Deaf
Blueberry rash

Question 3

Rubella

What is blueberry skin

Answer 3

intradermal erythropoisis

Question 4

Rubella:

Dx

Answer 4

maternal serology and viral culture

Question 5

MC torches infection

Answer 5

CMV

Question 6

CMV:

sxs (4)

Answer 6

• hearing loss (MC)
• periventricular calcifications
• dilated ventricles
• can get seizures

Question 7

CMV:

Dx

Answer 7

CMV isolation from urine (intranuclear inclusions)

- serology is bad test

Question 8

CMV:

Tx

Answer 8

IV ganciclovir (not great)

Question 9

HIV:

presentation at birth

Answer 9

assymptomatic

Question 10

HIV:

Tx

Answer 10

AZT until 2 negative viral cultures

Question 11

HSV:

Dz phase of mom effects

Answer 11

primary infection much more likely to spread than recurrent infection

Question 12

HSV:

when is it transmitted

Answer 12

MC intrapartum

Question 13

HSV:

presentation

Answer 13

-skin eye mouth disease
can disseminate –> brain + organs = fatal
- encephalitis
- any baby with meningitis/encephalitis = think HSV

Question 14

Syphilis:

disease state effects transmission?

Answer 14

increased risk of transmission if mom has primary

Question 15

Syphilis:

confirming health before discharge depends on what?

Answer 15

mothers serology

Question 16

Syphilis:

prenatal care?

Answer 16

mandatory pregnancy RPR

Question 17

Syphilis:

placental features

Answer 17

pale/thick/large

villositis with spirochetes

Question 18

Syphilis:

congenital sxs

Answer 18

hydrops fetalis, saddle nose, saber shins, rash on hands/feet, hutchinson’s teeth, deafness

Question 19

Syphilis:

Tx

Answer 19

procain PenG

Question 20

Hep B:

when does transmission to fetus occur

Answer 20

time of birth

Question 21

Hep B:

prevention?

Answer 21

screen mom for HepBsAg

Question 22

Hep B:

Tx for baby

Answer 22

give HBIG and Vaccine ASAP

Question 23

Hep B:

risks for infected baby

Answer 23

childhood hep B has increased risk of developing chronic hep. and hepatocellular carcinoma

Question 24

Intracranial calcifications seen in (2)

Answer 24

Toxo and CMV

Question 25

Diffuse calcifications and hydrocephalus

Answer 25

Toxo

Question 26

periventricular calcifications and microcephaly

Answer 26

CMV

Question 27

Chorioretinitis (blindness) (2)

Answer 27

Toxo, CMV

Question 28

Cataracts (2)

Answer 28

rubella, HSV

Question 29

Congenital cardiac disease

Answer 29

rubella (PDA usually)

Question 30

Bone lesions (2)

Answer 30

syphilis, rubella

Question 31

Vesicles (3)

Answer 31

HSV, VZV, Syphilis