Neutrophil Adhesion

Question 1

P/E Selectin

Answer 1

Found on endothelial surface and allow neutrophils to roll for weak adhesion
Sampling for chemoattractants (chemokines)

Question 2

ICAM

Answer 2

Found on the endothelial surface

Necessary for firm adhesion

Question 3

LFA-1

Answer 3

Found on neutrophil
Binds to ICAMs
Allows for firm adhesion

Question 4

PSGL-1

Answer 4

Found on neutrophil

Binds to P/E-Selectin

Question 5

CR1

Answer 5

Complement receptors

Allow binding to complement components

Question 6

FC Receptors

Answer 6

Bind to FC region of antibody

Question 7

Collectin receptors

Answer 7

Allow binding to MBP and CRP