Neutropenic sepsis Flashcards
1
Q
define neutropenic sepsis?
A
the development of sepsis in a patient with neutropenia
2
Q
diagnostic criteria of neutropenic sepsis?
A
o Temperature > 38 degrees
o Neutrophil count < 0.5 x 109 /L
3
Q
reasons of decreased neutrophil production?
A
- Chemotherapy
- radiotherapy
- bone marrow infiltration
- aplastic anaemia
- B12/folate deficiency
4
Q
reasons for accelerated turnover of neutrophils?
A
- Felty’s syndrome
- Hypersplenism
- malaria
5
Q
what to check in the history?
A
o High-risk features of neutropenia
o Recent blood products
o Intravascular devices
6
Q
what might be seen on examination?
A
o Pyrexia
7
Q
investigations for neutropenic sepsis?
A
- FBC (check neutrophil level)
* Blood cultures (check for sepsis)
