Neurotoxins And Venoms Flashcards
1
Q
What can neurotoxins be used for?
A
Immobilise prey, defence
2
Q
What do plants use?
A
Alkaloids amines; bitter tasting
3
Q
What’s in venom?
A
Polypeptides (proteins), venom usually multi-component
4
Q
What does Ouabain do?
A
Blocks ATPase site on Na+ - K+ pump
5
Q
What class of molecules do most neurotoxins target?
A
Gated ion channels
6
Q
TTX and Atracotoxin attacks what?
A
Voltage gated Na+ channels, binds extremely strongly, blocks the channel
7
Q
What do TEA, apamime and Dendrotoxin attack?
A
Voltage gated K+ channels
8
Q
What do conotoxins do to proteins?
A
Attack disulfide bridges