Neuroscience overview + intentions Flashcards

1
Q

Temporal resolution

A
  • Time between frames/measurements
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2
Q

spatial resolution

A
  • Ability to detect 2 adjacent structures as separate
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3
Q

Optogenetics

A
  • switch on/off neurons on basis of genetics with light
  • shine light on head + neurons in brain switched on/off
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4
Q

lesions + strokes

A
  • stroke-> occurs when blood flow in brain is disrupted
  • Allow experimenters to test hypothesis concerning functional role of damaged regions
    -limitations: don’t respect functional boundaries + can affect connections to other brain areas
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5
Q

Traumatic Brain injury

A
  • Trauma can cause destruction of neural tissue
  • frontal lobe more prone to damage from head trauma
  • damage can arise from collisions with the solid internal surface of the skull
  • can result in damage at site of blow or opposite site (reactive forces- countercoup)
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6
Q

Tumours

A
  • cause neurological symptoms by damaging neural tissue/ producing abnormal pressure on cortex + cutting of blood supply
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7
Q

Single dissociations

A
  • patient group snows impairment on one task +not the other
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8
Q

Double dissociation

A
  • one patient group shows impairment on one task + second patient group shows impairment on the other task
  • provides stronger evidence for selective impairment
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9
Q

influence + importance of case studies

A
  • understanding of brain beh relationships
  • indicated functional localisation
  • limitations of generalisability
  • case series studies look at overlap of multiple people + see which area is common to them all + the beh deficit
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10
Q

Phineas Gage case study

A
  • decision making + personality sig changes
  • shows frontal lobes role in personality + decision making
  • used MRI scans to better link sites of a brain damage to changes in beh
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11
Q

HM case study

A
  • Milner tested
  • Had amnesia as a result of bilateral surgery of the Medial temporal lobes to alleviate epilepsy
  • More evidence for functional localisation
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12
Q

Face bind- prosopagnosia

A
  • Damage to temporal lobes
  • Associative = can distinguish faces well but can’t recognise them
    -Apperceptive = struggle to differentiate between faces
  • Different lesions to the brain correlate with different types
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13
Q

Colour blind- achromatopsia

A
  • can be disrupted when lesions occur in temporal lobe
  • more common in males, genetics
  • Achromatopsia t prosopagnosia lesions overlap
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14
Q

Occipital lobe

A
  • Primary visual cortex in each hemisphere represent the contralateral hemifield
  • Anything on the left ends up in the right primary visual cortex
    -if the left cortex has a lesion you won’t see in the right field
  • GY is an example (lecture)
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15
Q

Blindsight

A
  • DB had surgery in primary visual cortex
  • blindsight der to describe the ability to discriminate between visual stimuli that weren’t consciously acknowledged as present by the patient
  • must be pathway from eye to brain that bypass primary visual cortex
  • classic blindsight cases can see motion of stimulus - shows preserved motion discrimination
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16
Q

Transcranial Magnetic stimulation - TMS

A
  • TMS coil is held by experimenter against ppt head
  • Pass a brief magnetic field through the coil which travels through skull + tissue to target specific parts
  • TMS pulse directly alters neural activity
  • can create a temporary lesion, overcoming limitations of lesion studies
17
Q

TMS + disruption of visual processing

A
  • visual perception disrupted when pulse occurs 80-120 MS after letter presentation due to disruption of neural activity in the visual cortex
18
Q

TMs of motion sensitive areas of the brain

A
  • Applied TMS to different regions of visual perception of motion
  • Targeting either area in translational = deficit compared to baseline
  • Radial motion only certain area has deficit
  • Rotational motion shows less deficit
19
Q

Experimental lesions

A
  • Animalmodels
  • surgical lesions
  • Advantages = precise, postmortem, test pre + post lesion
  • Disadvantages = ethical, generalisability, reorganisation
20
Q

chemical lesions

A
  • Animal models
  • Neurotoxins
  • Advantages = very precise
  • Disadvantages = generalising