Neuroscience Flashcards

1
Q

What two things are easy to forget to ask for in a headache history?

A
  • Any particular stress at the moment

- Any use of over the counter medication

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2
Q

In headaches what eye symptoms need to be asked about?

A

Need to ask whether the patient has migraines with or without aura.
Aura includes blurring of vision, black outs or black dots/zig zagged lines.

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3
Q

If someone presents with a collapse what do you ask?

A
When did it start? Sudden or Gradual?
What were you doing at the time?
Did you fall to the floor?
Did you loose consciousness ?
Did anyone witness the attack?
Did they say you were seizing? History of epilepsy?
Did you loose contience?
Did you injure yourself?
How did you feel before the collapse? Any change in vision?
How did you feel after collapsing? 
Did you have a headache?
Did you notice any weakness or numbness to limbs
Did you notice any changes to speech or vision?
Any episodes like this in the past?
Past head injury?
When was the last time they ate?
Any recent injury?
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4
Q

When asked about sudden onset weakness- what do you ask?

A
  • when
  • what were you doing
  • which limbs are affected
  • is one side or both sides affected
  • does the patient have numbness or lack of power anywhere
  • is the patient in any pain.
  • does the patient have any similar episodes like this in the past
  • any changes in visual or speech
  • suffered from any headaches
  • suffered from any loss of consciousness did they fall to the floor?
  • any cardiovascular changed
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5
Q

If someone has collapsed think of 3 possible causes?

A

Abdominal pain or headache —> subarachnoid haemorrhage or AAA
Abdominal pain: ectopic pregnancy
Diabetic patients: ask when they last ate

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6
Q

Compare and contrast extra dural and sub dural haematomas

A

Subdural: rupture of bridging veins. There will be a fluctuating level of consciousness over a couple of weeks

Extradural: fracture of the temporal bone leading to tear of the middle meningeal artery. This will lead to brief unconsciousness. Then a lucid interval and then rapidly deteriorating condition as the ICP increases

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7
Q

What are 4 signs of an increase in ICP

A

Headaches
Confusion
Seizures
Vomiting

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8
Q

3 features of Parkinson’s:

A

Rigidity
Bradykinesia
Resting Tremor
+ stoop, decreased smell and stooped posture

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9
Q

HEADACHES: WHAT SHOULD YOU ALWAYS ASK??

A

Pain in scalp
Watering Eye
Rhinorrea

Miosis or ptosis
** All above are symptoms of a cluster headache**

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10
Q

What is the treatment of MS:

A

Acute: steroids (IV methylprednisolone)
Chronic: Interferon IB or IA
+ dimethyl fumarate
Symptomatic treatment give Baclofen and Botox injections

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11
Q

Treatment of Myasthenia Gravis

A

Diagnosed with anti-AChR antibodies

Pyridostigmine (anti-cholesterase)

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12
Q

MND treatment

A

Anti-glutamergic drug Riluzole

Spasm: baclofen
Analgesia: NSAIDs

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13
Q

What is MS?

A

It is a chronic autoimmune T cell mediated inflammatory response of the CNS. It involves multiple plaques of demyelination in the brain and spinal cord. Affects oligodendrocytes and only brain white matter!

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14
Q

Name the 3 types of MS

A

Relapsing Remitting
Secondary Progressive
Primary progressive MS: worse from the start no release or remitting sections

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15
Q

MS: what do people initially present with? And name a few other symptoms:

A
Unilateral optic neuritis (pain in one eye) and reduced central vision 
Numbness and tingling in the limbs 
Leg weakness
Cerebellar symptoms 
Trigeminal neuralgia 
Bladder and sexual problems
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16
Q

MS: what needs to occur to get a diagnosis

A

Two or more attacks affecting different parts of the CNS,

Need to do a MRI and a Lumbar puncture (will show oligoclonal lgG bands.

17
Q

Guillan Barre Syndrome: what is the diagnostic method and what is the treatment?

A

Nerve conduction studies
Lumbar puncture
Spirometry

Treatment: IV Immunoglobulin for 5 days
Also give enoxaparin as there is an increased risk for a DVT!

18
Q

What is the treatment for SAH

A

Coiling

Nifedipine a CCB that prevents vasospasms

19
Q

What should the treatment after a stroke be? Name 4 drugs

A

Aspirin
Clopidogrel
Statin
Ace inhibitors

20
Q

Name two drugs used in dementia

A

Donepezil

Rivastigmine

21
Q

What organ will likely be the cause of Myasthenia gravis in a young man

A

Thymus