Neuroplasticity and strategies to improve motor function - Lecture #1 Flashcards

1
Q

What is neuroplasticity?

A

The brain’s ability to reorganize itself so it forms new neural connection
Due to:
- training response
- practice
- to compensate for injury or disease

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2
Q

What is neurogenesis?

A

Continous generation of new neurons in certain brain regions

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3
Q

How are new neural connections created?

A

New skills and experiences

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4
Q

What assists with strengthening synapses?

A

Repetition and practice

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5
Q

Neuroplasticity can take place when changes occur in what?

A
  • characterisitcs of dendritic spines
  • Properties of membrane and ion channels
  • Hormonal activity
  • Microglia activity
  • DNA regulation and transcription
  • Neurotransmitters
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6
Q

How is neuroplasticity created with motor learning?

A
  • repetition (need to repeat)
  • neuroadaptive (able to adapt)
  • engaging (attention)
  • rewarding (worth it)
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7
Q

What is neuroadaptive?

A

Task parameters to be constantly modified

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8
Q

How do we engage motor learning to increase neuroplasticity?

A

Constant task difficulty adjustments (learn by making it hard)

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9
Q

What do we engage for the motor learning system?

A
  • dopaminergic reward system
  • noradrenergic detection system
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10
Q

Task-specific intervention requires what?

A
  • Extensive practice of a specific task
  • emphasizes functional mobility task
  • practice over everything
  • changing: task, environment, difficulty — progress when needed
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11
Q

What is motor control?

A

The ability to regulate the mechanism that is essential to movement

Second to second
Minute to minute control of a muscle

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12
Q

What is motor skill?

A

Actions that require the body, head and limb movements to achieve a goal
- skill assumes both control and coordination

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13
Q

What is motor learning?

A

Gaining new skills needed to plan and do a desired movement pattern for a task

  • Day to Day
  • Week to week control of the muscles to do an activity
  • Motor control over time
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14
Q

Describe performance

A

Doing a skill at a specific time and situation

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15
Q

What is open loop?

A

Does not use feedback
Control center provides all the info for effectors to carry out movement

No feed back to keep the movement going

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16
Q

What is closed loop?

A

uses feedback
control center issues information to effectors = enough to initiate movements

Needs feedback to keep or stop movement

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17
Q

What is the cognitive stage?

A
  • Understanding the task and developing strategies
  • Large amount of attention

“What to do?”

Instructive

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18
Q

What is associative stage?

A
  • Select the best strategy for the task -> refine skill
  • some attention still required

“How to do”

Reinforcement
- Use dependent

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19
Q

What is autonomous stage?

A
  • skills becoming automatic
  • low degree of attention needed

“How to succeed”

Sensorimotor adaption
- use dependent

20
Q

What is the PT’s role to increase motor function?

A
  • Know the patient’s strengths and limitation
  • Develop a collaborative PoC that has goals and outcomes to match pt personal needs
21
Q

How do tasks affect movement?

A

Types of goals/nature
Changable elements

Attributes such as:
- mobility
- stability
- skill

22
Q

What are some personal characteristics that affect movement?

A

Cognition
Sensation/perception
Motor function
Impairments
Comorbidities/complications
Overall health status

23
Q

How does the environment affect movement?

A

Physical features:
- regulatory (stable)
- nonregulatory (unstable)

Social resources

24
Q

What is the first level of the neurorehab intervention?

A

Restorative interventions = promote and restore optimal functional capacity

25
What is the **second level** of the neurorehab intervention?
**Functional training** = uses normal patterns to get the task and motor learning strategies | Acitivity based, task-oriented interventions
26
What is the **final level** of the neurorehab intervention?
**Compensatory intervention** in the presence of severe impairment = promote optimal function with altered movement patterns and strategies for entire body
27
What are the key variables of motor learning?
1. Practice and repetition 2. Performance feedback 3. Generalizability and variability 4. Diverse activities in varied contexts
28
What is the most important variable in motor learning?
Practice - What/how a task is practiced > simple repetition
29
What is blocked practice?
Practicing **a skill** constantly during a session
30
What is a random practice?
Practicing **multiple skills** rather than concentrating on one single skill during a session
31
What is important during performance feedback?
Intrinsic (feeling the task) Extrinsic (external force) Knowledge of results and performance
32
What is important aspect of motor learning?
Patient has to solve the problem
33
Is too much feedback good?
Too much feedback can change performance = patients are not able to create true learning and skill carryover
34
What is self feedback?
Task intrinsic feedback
35
What are the other forms of external feedback?
- demonstration - visual - tacticle - verbal - auditory - biofeedback - neurofeedback
36
What are the other forms of verbal feedback?
Knowledge of results - info about the outcome Knowledege of performance - info about the characterisitics (parameters)
37
How are we able to change generalizability and variability?
- Different settings, surfaces, assistance, type of day
38
How are we able to change activities?
To **have diverse activities** in varied cortex by: - blocked vs random practice - changing task - different environemnt
39
What is a transcranial magnetic stimulation?
An **electromagnetic coil** held against the head and short electromagnetic pulses = depolization or hyperpolarization of the neurons in the brain leads to stimulation of nerve cells in the brain region
40
How do we use forced use as an intervention?
Designed to "force" the patient to use the affected extremity - immobilization of **unaffected** side - encouraging use **affected** side
41
What is the principle of constraint induced movement therapy?
- **intense practice using involved UE** - use of a "constraint" for the uninvolved UE - use of the involved UE for all activities throughout the day
42
How are we able to use virtual reality and game systems?
- patients to perform movement in a simulated environment with feedback - using of various games to advance activities
43
What are virtual reality and game systems generally used for?
For UE mobility, LE weight bearing, sitting balance and standing balance
44
How is the body weight support treadmill operated?
Body weight is supported with a harness/overhead counterweight system (lite-gait) - support for excessive weakness - Manual assistance for normal stepping pattern/kinematic
45
How does BW support treadmill assist with rehab?
Increases the number of steps a person is able to take = HIGT