Neurophysiology basics + Membrane ion chanels Flashcards
Describe Action Potential
An Electrical event in the neuron where the neuron membrane changes from an area of postive to negative and back to negative.
-this AP is an electrical impulse that travels down length of neuron to another cell
POSTIVE sodium ions are in high concentration _______ the cell and want to move _______ the cell.
sodium ions are in high concentration OUTSIDE the cell and want to move INSIDE the cell.
POSTIVE Potassium ions are in high concentration _______ the cell and want to move _______ the cell.
Potassium ions are in high concentration INSIDE the cell and want to move OUTSIDE the cell.
outside the cell what are there larged amounts of?
negative chloride ions
inside the cell what are there large amounts of?
negativiely charged proteins
First of all, what are membrane ion channels?
Membrane protiens
Describe a Leak Channel
-memebrane proteins that include passive transport (no energy) of differnt substances
-ALWAYS open. 7/11 of channes.
-go down concentration gradient
-specific to each ion!!
Describe Gated Channels and what are the three main types?
Gated channels are membrane proteins that allow ions to pass though only during certain circumstances.
-REQUIRES ENERGY!!
3 types
1.chemically gated
2.Voltage gated
3.mechanically gated
Chemically gated channels
open only if a chemical (like a neurotransmitter) binds to the membrane protien.
Voltage gated channels:
-rely on change on membrane potential. (ELECTRICAL change)
-there is usally a voltage setting when they open and a voltage setting when they close.
-exampels: K+, Na+, and CA+ channels
Mechanically gated channels
-open or close in response to a physical distrortion (pressure).
ex: Sensory receptors for touch