Neurophysiology 1

Question 1

What are the 3 advancements of neurophysiology?

Answer 1

1. Invention of microelectrode
2. Development of anatomical method
3. Ability to visualize grouping of cells in cortex

Question 2

Where do is the first synapse of binocular vision?

Answer 2

V1, visual cortex

Question 3

Where does the visual signal go to (in order) in the visual cortex?

Answer 3

LGN –> V1 layer 4 –> layer 2 and 3 –> layer 5 —> layer 6

Question 4

What column in the ocular dominance columns are ipsilateral?

Answer 4

1 and 7

• 1 = contralateral
• 7= ipsilateral

Question 5

What type of amblyopia is this?:

OD: plano -0.50 x 090 OS: +3.50 -0.50 x 090

Answer 5

Anisometropic Refractive Amblyopia, OS

Question 6

Which location within the visual system
indicates the first place where visual
information from both eyes are converged?

Answer 6

V1 or striate cortex

Question 7

Hubel and Wiesel’s 1965 research on
monocular deprived kittens (lid sutured for 3
months) resulted in which recorded ocular
dominance histograms?

Answer 7

All cells are in column 1 OR 7

Question 8

Monocular sensory deficits include what 3 things?

Answer 8

1. Reduced optotype
2. Reduced contrast sensitivity
3. Reduced spatial localization and vernier acuity

Question 9

Binocular sensory deficits include what 2 things?

Answer 9

1. impaired stereopsis

2. Reduced binocular summation

Question 10

Visual acuity is limited by what?

Answer 10

Cone spacing

Question 11

Abnormal spatial vision is due to a deficit where?

Answer 11

Cortex, V1

Question 12

An abnormal contrast sensitivity function is found in what type of amblyopes more?

Answer 12

Anisometropic (vs. strabismic) amblyopes

Question 13

What finding in the eye leads to generalized reduced CSF?

Answer 13

Overall defocus/deficit

Question 14

At what level of contrast sensitivity are Anisometropes worse at? Strabs?

Answer 14

• high spatial frequencies

- all spatial frequencies

Question 15

This causes the amblyopic eye to make false judgements about positional locations of objects in space.

Answer 15

Spatial aliasing

Question 16

This type of amblyope did worse in optotype and vernier acuity compared to grating acuity but has better contrast sensitivity.

Answer 16

Strabismic Amblyope

Question 17

This type of amblyope had vernier and optoptype acuity proportional to grating acuity, but poor contrast sensitivity

Answer 17

Anisometropic amblyopes

Question 18

Where do strabismic pxs fall on the amblyopia map?

Answer 18

northern

Question 19

Where doe anisometropes fall on the amblyopia map?

Answer 19

southern

Question 20

The crowding effect is more of an issue in what type of amblyope?

Answer 20

Strabismic

Question 21

T/F: Anisometropic amblyopes can have normal summation at low spatial frequencies but none at high spatial frequencies.

Answer 21

True