Neurophys block 4 Flashcards
Describe the subdivisons of the CNS
Brain
- receives and processes info from PNS
-initiates responses
- stores memories, thoughts, emotions
Spinal cord
- conducts signals to and from CNS
- controls reflex
List all 7 parts that make up a neuron
- Dendrites
- Cell Body/ Soma/ Pericaryon
- Axon Hillock
- Axon Hillock/ Trigger zone
- Presynaptic Terminal
- Myelin Sheath
- Nodes of Ranvier
What is the function of dendrites?
Receives info
What is the function of the cell body/ stoma/ pericaryon?
Contains organelles
What is the function of the axon?
Carries info, passes messages
What is the function of the Axon Hillock/ Trigger zone?
The origin of the axon, it makes the action potential (AP)
What is the function of the presynaptic terminal?
It is the end of the axon, transmits info
What is the function of the myelin sheath?
-enhances speed of info transfer
-Produced by Schwann cells in the PNS and Oligodendrocytes in the CNS
-saltatory conduction
- Faster depol is unmyelinated cells
Small axons < 1um are unmyelinated
Nodes of Ranvier
- gaps in between myelin sheaths
-Generates AP, jumps from node to node
Glial cells in the CNS?
- Microglial
- Astrocytes
- Oligodendrocytes
- Ependymal cells
Glial cells in the PNS?
Schwann cells (makes myelin in the periphery)
Functions of glial cells
- helps make myelin
- modulates growth in damaged neurons
- buffers conc. of K+ and neurotransmitters
- helps form synapses INDIRECTLY
-Helps with immune responses
Microglial cells
(Glial cells in the CNS)
- brain immune cells
- act as macrophage to clear debris (phagocytosis)
- releases NO to prevent viral replication
- protects and helps develop the brain
-destroys unnecessary synapses
Astrocytes
(Glial cells in the CNS) - 50%
- structural and metabolic support for neurons
- forms inner/outer glial membrane
-releases neurotrophic factors
- helps elongate axons/dendrites
- helps w repair (regeneration)
-helps maintain BBB
CONTROLS:
- levels of neurotransmitters
- conc. of ions (has ion channels)
Oligodendrocytes
(Glial cells in the CNS)
-supports axons
- can touch multiple axons @ the same time
-makes myelin in CNS, speeds up conduction
Ependymal cells
(glial cells in CNS)
- creates cerebrospinal fluid (CSF)
-covers ventricles in brain, central canal of CNS, choroid plexus in medulla oblongata
Schwann cells
(glial cell in PNS)- also called neurolemmocytes
- makes myelin in periphery
-side by side axon, provides support
Structural classification of neurons
- Multipolar- most common. 1 axon, many dendrites
- Bipolar- 2 processes. 1 axon, 1 dendrite
- Pseudo-unipolar- single stem process that forms 2 processes. 1 goes to PNS, other goes to CNS. Sensory afferent- info from PNS to CNS
Functional classifications of neurons
- Sensory/ Afferent
- Interneurons/ Association
- Motor neurons/Efferent
Sensory/Afferent neurons
info from PNS to CNS
mostly PSEUDO-UNIPOLAR
Interneurons/Association
in the CNS
Connects motor and sensory neurons
mostly MULTI-POLAR or BIPOLAR
Motor/ Efferent neurons
info from CNS to PNS (muscle/glands)
mostly MULTIPOLAR