Neurophisiology 1: Action Potential Flashcards
What’s the purpose of neurons?
Not just transmission! They Transform information, and then sent the processed info to other neurons
What is the tool used to measure action potential?
Electrode
How do you call action potential activity measurements? (initials: E R)
Extracellular recordings
What are ions?
Molecules that have an electrical charge
Can Ions just pass through the membrane?
No, because the membrane is impermeable to water soluble molecules
Membrane proteins in the neuron
Sodium-potassium pump, voltage-gated sodium channels, voltage-gated potassium channels,non-gated potassium channels and voltage-gated calcium pumps
inside/outside concentration of Na+ at resting potential
less inside more outside
Forces acting upon ions (2)
eteronormativi comunisti!
- Diffusion: high concentration to low concentration (ioni comunisti!)
- electrostatic forces: minus with plus (ioni eteronormativi!)
What happens to the neuron when it depolarizes?
It becomes a little less negative inside
What are the names of the 2 equations that predict ion potentials (will get more specific in other cards)
Nerst and Goldman
What does the Nerst equation predict?
Nerst predicts the equilibrium potential of a given ion, based on this ion’s concentrations inside and outside the membrane.
What does the Goldman equation predict?
Goldman predicts the potential difference across a membrane at equilibrium potential (?)
What is hyperpolarization?
Increasing negativity (-) in the inside of the neuron
What is depolarization?
The inside of the neuron becomes less negative
What is a treshold?
The local voltage at which the next segment of the membrane opens their ion channels and so on
