Neuropathy and encephalopathy Flashcards
1
Q
Peripheral neuropathy- Sx
A
- Sensory, motor or mixed deficits
- Axonal degeneration
- Paresthesias, pain, muscle tenderness
- Depressed or absent tendon reflex
- Due to DM, arteritis, leprosy
2
Q
Peripheral neuropathy - Dx
A
- Nerve conduction velocity and eletromyography
- Slowed responses
3
Q
Peripheral neuropathy - Tx
A
- Underlying cause
- Gabapentin for dysthesia and neuralgia
4
Q
Acute idiopathic polyneuropathy, GBS- Sx
A
- Proximal weakness, symmetric distribution
- Begins in legs
- Distal paresthesias, radicular pain
- Tachycardia, hypo/hyperTN, facial flushing, impaired sphincter control
- May follow infections, inoculations or surg procedures
5
Q
Acute idiopathic polyneuropathy, GBS-Dx
A
- High CSF protein
- Nerve conduction- marked abn
- Pathology- demyelination
6
Q
Acute idiopathic polyneuropathy, GBS-Tx
A
- Volume or pressers for hypotn
- Heparin to prevent PE
- IV immunoglobulin
- Resp toilet and chest PT
7
Q
Wernicke encephalopathy- Sx
A
- Confusion, ataxia, nystagmus leading to ophthalmoplegia
- Lateral rectus muscle weakness and conjugate gaze plasies
- Peripheral neuropathy
- Due to thiamine deficiency, alcoholism
8
Q
Wernicke encephalopathy- Dx
A
- Thiamine deficiency
- Response to tx
9
Q
Wernicke encephalopathy- Tx
A
- IV Thiamine, IM thiamine, proper diet
10
Q
Hepatic encephalopahty- Sx
A
- Metabolic encephalopathy
- Day night, reversal
- Asterixis, tremor, dysarthria
- Mild confusion to drowsiness to stupor to coma
- Failure to detox- ammonia
11
Q
Hepatic encephalopahty- Dx
A
- LFTs
- Elevated ammonia
12
Q
Hepatic encephalopahty- Tx
A
- Latulose
- Neomycin sulfate
- Withhold/ restrict protein
13
Q
Charcot-Marie-Tooth- Sx
A
- Foot deformities and gait disturbances
- Pes cavus
- Polyneuropathy, distal weakness and wasting in legs
- Distal sensory loss, depressed or absent tendon reflex
- Axonal loss
14
Q
Charcot-Marie-Tooth- Dx
A
Nerve conduction velocity
- Cutaneous nerve biopsy
15
Q
Charcot-Marie-Tooth- Tx
A
- PT
- Compression socks
