Neuropathies

Question 1

isolated anterolateral thigh numbness without numbness

Answer 1

Meralgia Paresthetica ( a compressive neuropathy of the lateral femoral cutaneous nerve)

Treat by relieving pressure

Question 2

Sensory loss over palmar surface of first three digits and weakness with thumb abduction and opposition

Answer 2

Median Neuropathy ( carpal tunnel syndrome)

Wrist splints or glucocorticoid injections for mild disease
surgical release if severe

Question 3

Numbness of 4th/ 5th fingers, interosseous muscle weakness

Answer 3

Ulnar Neuropathy - Elbow Splinting or Elbow pads

Surgical Release if severe

Question 4

pain tingling/ numbness over great toe of foot and along medial foot

Answer 4

tarsal tunnel syndrome

Local glucocorticoid injection

Question 5

upper and lower face weakness

Answer 5

Bells Palsy

Prednisone if within 72 hours

Question 6

Multiple noncontiguous nerve deficits (mononeuritis multiplex)

Answer 6

Consider Vasculitis (especially if painful), lymphoma, amyloidosis, sarcoidosis, lyme disease, HIV, leprosy and diabetes

Question 7

Distal and Symmetric (stocking glove) sensory or sensorimotor

Answer 7

Axonal Polyneuropathies ; DM and Alcohol are the most common causes, small fiber neuropathy will present with pain only

Question 8

Severe Unilateral Leg pain, numbness, proximal weakness, atrophy and weight loss

Answer 8

Diabetic Lumbosacral Radioplexus Neuropathy

Question 9

Acute Ascending, Areflexic paralysis and paresthesias often preceded by GI illness (Campylobacter infection) CSF shows elevated protein and a normal cell count (albuminocytologic dissociation

Answer 9

Guillain Barre Syndrome

Treat with Plasma Exchange or IVIG

Question 10

Symmetric Distal Sensory Neuropathy in the setting of MGUS, Multiple Myeloma, amyloidosis and cryoglobulinemia

Answer 10

Paraproteinemic Neuropathy

Treat underlying disorder `