Dementia

Question 1

Early and prominent personality changes, behavioral disturbances including disinhibition and impulsivity, diminished frontal or temporal lobes on MRI, onset before age of 60 years

Answer 1

Frontotemporal dementia, behavioral variant

Question 2

Dementia, shuffling gait, urinary incontinence and ventriculomegaly in the absence of past history of meningitis, SAH or trauma

Answer 2

NPH

Question 3

Choreoathetosis (involuntary twitching) and Dementia, autosomal dominant pattern of inheritance

Answer 3

Huntingtons Disease

Question 4

Prominent myoclonus, characteristic EEG pattern of triphasic sharp waves, CSF protien 14-3-3, rapidly progressive onset at early age

Answer 4

Creutzfeldt Jakob disease

Question 5

Early Postural instability/ falls/ apathy, parkinsonism, poorly responsive to levodopa, vertical gaze palsy

Answer 5

Progressive Supranuclear Palsy

Question 6

History of head injury followed by delayed development ( 10 years) of impaired concentration, short term memory loss, executive dysfunction, and judgement, aggression, depression, irritability, violent behaviors, and suicidality, parkinsonism, unsteady gait, shuffling gait, slurred speech

Answer 6

Chronic traumatic encephalopathy

Question 7

Mild Parkinsonism characterized by postural instability and gait difficulty, fluctuating cognition, delusions and VISUAL HALLUCINATIONS

Answer 7

Dementia with Lewy bodies

treat with acetylcholinesterase inhibitor

Question 8

What are common side effects of Acetylcholinesterase inhibitors?

Answer 8

Bradycardia, Heart block, diarrhea, nausea and vomiting and syncope

Question 9

true or false: Combination therapy with an acetylcholinesterase inhibitor and memantine is superior to acetylcholinesterase inhibitor alone

Answer 9

False

Question 10

Severe Orthostatic Hypotension and ataxia

MRI showing Necrosis of the putamen and cerebellar atrophy

Answer 10

Multiple System Atrophy