Neuropathie phériphérique Flashcards

1
Q

Étiologies de neuropathie périphérique axonale:

A
Diabète
Alcoolisme chronique
Insuffisance rénale 
Médicamenteuses et toxiques
Amylose
VIH phase tardive
Vascularite
Dysthyroidies
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2
Q

Étiologies mononeuropathies multiples

A

Maladies de systèmes : PAN, sarcoidoise, cryoglobulinémie
Diabète
Lèpre

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3
Q

ENMG neuropathies démyelinisantes

A

Ralentissement des vitesses de conduction motrices
allongement de la latence des ondes distales motrices
Allongement de la latence des ondes F

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4
Q

ENMG neuropathie axonale

A

Vitesses normales
Baisse d’amplitude du potentiel d’action moteur
Baisse d’amplitude du potentiel sensitif

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5
Q

Etiologies hyperproteinorachie isolée

A

Guillain Barré
Diabète
?

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6
Q

Principales polyneuropathies démyelinisantes

A

Neuropathie à IgM monoclonale à activité anti MAG

Polyneuropathie de Charcot Marie Tooth

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7
Q

Médicaments responsables de polyneuropathies sensitives

A
Cytostatiques : vincristine et platines
Thalidomide
Izoniazide
Amiodarone
Nitrofurantoïn, ARV 
Disulfirame
Chloroquine
Métronidazole
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8
Q

Anomalies cliniques polyneuropathie toxique alcoolique

A

Aréflexie calcanéenne
Amyotrophie
Déficit moteur prédominant sur la loge antero latérale de la jambe

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9
Q

Étiologie mononeuropathie sensitive

A

Anticorps anti Hu : cancer pulmonaire à petites cellules
Syndrome de Gougerot Sjogren
Origine dysimmunitaire sans cause
Sels de platine des chimiothérapies

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10
Q

Étiologie mononeuropathie multiple

A
PAN
Sarcoidose
Cryoglobulinemie
Diabète
Lèpre
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11
Q

Neuropathie la plus fréquente dans le monde

A

Lèpre mononeuropathie multiple

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12
Q

Médicaments provoquant des neuropathies périphériques

A

Polyneuropathies médicamenteuses et toxiques:

  • Cisplatine
  • Vincristine
  • Thalidomide
  • Taxanes
  • Isoniazide, nitrofurantoïne, antirétroviraux
  • Métronidazole, chloroquine, disulfirame
  • Amiodarone
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13
Q

Causes de neuronopathies motrices

A

Plomb
SLA
Syndrome lymphoproliferatif

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