Neurons, neurotransmitters drugs and mental function Flashcards

Lecture 6

1
Q

Facts about the synapse.

A
  • This is the name of the connection between neurons.
  • There are many synapses linking one cell to another.
  • when an action potential arrives at an axon terminal, neurotransmitters are released at the synaptic cleft.
  • receptors at the postsynaptic neuron responds to the neurotransmitter and generates a graded potential.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define synaptic cleft..

A

The synaptic cleft is the space between the presynaptic neuron and the postsynaptic neuron.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define receptors.

A

Receptors are specific vesicles.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Explain the process of neurotransmission.

A
  1. A message travels from the dendrites through the cell body and to the end of the axon.
  2. The message causes the chemicals, called neurotransmitters, to be released from the end of the axon
    into the synapse. The neurotransmitters carry the message with them into the synapse. The synapse is
    the space between the axon of one neuron and the dendrites of another neuron.
  3. The neurotransmitters then travel across the synapse to special places on the dendrites of the next
    neuron, called receptors. The neurotransmitters fit into the receptors like keys in locks.
  4. Once the neurotransmitter has attached to the receptors of the second neuron, the message is passed on.
  5. The neurotransmitters are released from the receptors and are either broken down or go back into the
    axon of the first neuron
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Define vesicles.

A

Bag of joy.
They contain 1000’s of neurotransmitter molecules.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Define diffusion in the process of neurotransmission.

A

Eventually neurotransmitters molecules must be cleared from the synaptic cleft. Some drift away and this is called diffusion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Sometimes neurotransmitters are taken back up into the presynaptic neuron in a process called….

A

Reuptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Synthesis, storage, release, binding and reuptake

A

The process by which ideas and images are combined and formed into objects of thought or by which objects of consciousness are brought together into meaningful words.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What can have an effect by altering the neurotransmission at synapses?

A

Drugs
- these drugs can slow it down or speed it up
- you can alter storage of neurotransmitters.
- you can block those receptors
- you can also slow down reuptake of the neurotransmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Define agonists.

A

These are drugs that bind to a receptor of a cell and trigger a response by the cell. They often mimics the action of a naturally occuring substance.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is an indirect agonist?

A

They enhance the release or action of an endogenous neurotransmitter.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Define antagonist.

A

This is a drug that binds to the receptor either on the primary site, or on another site, which all together stops the recepetor from producing a response.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Name a few neurotransmitters in the brain.

A

Serotonin, Dopamine, glutamate, acetylcholine, and horadrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name a few neurotransmitters in the brain.

A

Serotonin, Dopamine, glutamate, acetylcholine, and noradrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name an example of an agonist and antagonist drug.

A

Nicotine and scopolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is used to improve Parkinson’s disease?

A

Deep brain stimulation