Neurons + Glia Flashcards

1
Q

What are the 6 types of glial cells

A

Schwann Cells
Ogliodendrocytes
Astrocytes
Radial Glia
Micro glia
satellite cells

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2
Q

What is the job of Schwann cells

A

produce myelin in the PNS

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3
Q

What is the job of Ogliodendrocytes

A

Produces myelin in the CNS

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4
Q

What is the job of Satellite cells

A

Supports the PNS

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5
Q

What is the job of Astrocytes

A

Supports the CNS (most numerous)
- Dilate blood vessels
- maintain chemical environment
- Maintains the Blood-brain barrier

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6
Q

What is the job of Radial Glia

A

Stem cells (Not glia)
Guides migration of Neurons during embryo

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7
Q

What is the job of Microglia

A

CNS macrophages (act as Phagocytes)
- Removes Dead, dying, damaged neurons
- Removes waste material from brain
- mobilized after infections

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8
Q

Where are Astrocytes found

A

White matter

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9
Q

What does the Blood brain barrier do

A

Surrounds brain and blocks out most chemicals and protects the brain as most neurons in brain tend not to regenerate

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10
Q

How do certain chemicals get past the Blood-brain barrier

A

Fat-soluble, glucose, amino acids utilize active transport to cross the barrier

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11
Q

What does myelination aid in

A

Insulating axons and clustering sodium channels at the nodes of Ranvier

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12
Q

What nourishment do vertebrate neurons require

A

Depends entirely on glucose

Needs a steady supply of oxygen
(20% of O2 is used by brain)

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13
Q

Where are the Motor neuron Somas located within the spinal cord

A

The Ventral horn

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14
Q

Where are the Sensory neuron somas located within the spinal cord

A

The Dorsal Root Ganglion

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15
Q

What are the uses of adhesion molecules at synapse terminals

A

to keep synapses tight and together and with synapse formation

plasticity helps to change synapses

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16
Q

How do proteins/vesicles get to synapse

A

Proteins and Vesicles moves along microtubule cytoskeleton

17
Q

What are microtubules made from

A

Protofilament

18
Q

What aids in the structure of the Axons

A

Actinfilament/Neurofilament + Microfilament

19
Q

Which end of the microtubules in Axons point away from the cell body

A

the Positive (+) end

(this is mixed in dendrites)

20
Q

What is the plus end of the microtubules made of

A

Constructed by Tublin dimers (alpha , beta tublin)

21
Q

What are the two motor proteins

A

Kinesin + Dynein

22
Q

Which protein moves Anterograde

A

Anterograde = walk to (+) end from cell body

Kinesin

23
Q

Which Motor Protein moves Retrograde

A

Retrograde = Walks to (-) end to the cell body

24
Q

What does Kinesis do

A

Walks anterograde and moves adhesion proteins, other proteins and membranes down to end

25
Q

What does Dynein do

A

walks retrograde back up
- Makes repairs on neuron
- moves growth factors from axon terminals to nucleus
- moves signals from Axons to nodes