Neurons and neurotransmitters Flashcards
What does the cell body of a neuron do?
It contains the nucleus and is connected to the dendrites. Most important role is manufacturing new cell components
Which part of the neutron receives the electrical messages from other neurons?
Dendrites
What is the myelin sheath?
A protective covering over the axon. Speeds up synaptic transmission.
The sheath contains gaps along the axon called nodes. The neural signal jumps from node to node and this is how transmission is sped up
What is an axons role in a neutron?
Conducts the electrical impulses from the cell body to send to other neurons as a message
Explain resting potential.
The resting state involves an imbalance in charge across the cell membrane. Inside is more negative than outside
Explain graded potential
Are electrical charged caused by signals from other neurons. Can be either excitatory or inhibitory.
What is an excitatory graded potential?
Depolarisation.
Membrane potential becomes more positive. This makes it closer to the firing threshold which makes the neuron more likely to fire!!
What is an inhibitory graded potential?
Hyperpolarisation.
Membrane potential becomes more negative and moves further away from the threshold which makes the neuron less likely to fire.
Glial cells
Surround neurons and provide support and insulation between them
What is the synapse?
The synapse is the fluid filled gap between the neurons that the neurotransmitters travel through.
What does pre and post synaptic mean?
Refers to the positioning before or after the synapse
Describe the process of synaptic transmission
- Vesicles inside the axon containing neurotransmitters
- the vesicles fuse with the membrane and the neurotransmitters cross the synapse
- the neurotransmitters attach to the dendrites and produce a graded potential
What happens after the synaptic transmission?
The transmitter is then inactive and released from the receptor site. It will then either make its way back to the pre-synaptic cell (re-uptake) or be broken down by enzymes.
How does the lock and key model fit into the nervous system?
The lock and key model describes how the post-synaptic receptor sites are very specific and only specific neurotransmitters are accepted into the site
What is glutamate?
Main excitatory transmitter.
Involved in learning, memory and transfer of sensory input
What is GABA?
The main inhibitory transmitter.
Dampens neural activity - involved in learning, memory and sleep
What kind of drugs increase the activity of GABA?
Anti-anxiety.
Used to suppress overactive brain roles linked to worry.
What is acetylcholine (ACh)?
Muscle contractions