neuronal communication Flashcards
outline the ways in which the structure of a motor and sensory neurone are similar
both have 1 dendrite(s) ; 2 an axon ; 3 a cell body with a , nucleus / named organelle ; 4 myelin sheath / myelinated / (covered with) Schwann cell / nodes of Ranvier ; 5 voltage-gated channels / sodium-potassium (ion) pump ; QWC dendrite(s) axon(s) cell body(ies) myelin (or derived term) schwann
Why is the Pacinian corpuscle described as a transducer?
it converts energy (mechanical) into ,
another / different , form of energy (electrical)
Deformation of the plasma membrane of the tip of the neurone causes the membrane to become more permeable to Na+. Suggest why.
idea that deformation of membrane will allow more Na+
through because
1 (the increased pressure) causes
sodium (ion) channels to open ;
2 (temporary) gaps / holes / spaces , appear ,
between the phospholipids / in the bilayer ;
The generation of an action potential follows the ‘All-or-Nothing’ law.Explain what this means.
if the , stimulus is not strong enough /
threshold (value) is not reached /
depolarisation (of membrane) is insufficient ,
then , it / an action potential , is not ,
generated / AW ;
Describe how information about the strength and intensity of a stimulus is communicated to the brain.
1 idea that it is represented by the frequency of the
action potentials ;
2 high , frequency / rate (of generation) ,
of action potentials shows ,
a strong / an intense , stimulus ;
Suggest an explanation for the fact that action potentials are not generated constantly whilst wearing clothes.
action potentials not generated because 1 sodium (ion) channels (remain) open / resting potential not re-established ; 2 idea of ions being in the wrong place for correct ion movement (across membrane) ;
Outline the roles of synapses in the nervous system.
1 allows , neurones to communicate / cell signalling ;
2 ensure transmission (between neurones)
in one direction (only) ;
3 allows , convergence / impulses from more than one
neurone to be passed to a single neurone ;
4 allows , divergence / impulses from a single neurone
to be passed to more than one neurone ;
5 idea that filters (out) , ‘background’ / low level , stimuli
or
ensures that only stimulation that is strong enough
will be passed on ;
6 prevents fatigue / prevents over-stimulation ;
7 allows many low level stimuli to be amplified ;
8 idea that presence of inhibitory and stimulatory
synapses allows impulses to follow specific path ;
9 permits , memory / learning / decision making ;
Name one chemical that transfers a nerve impulse from one neurone to another.
acetylcholine
Suggest the part of the neurone where the plasma membrane has TRPA1 receptors.
either
post-synaptic membrane ;
(TRPA1) prevents attachment of (named) neurotransmitter
to its receptor ;
or
pre-synaptic membrane / (pre)synaptic knob /
axon terminal / bouton / synaptic bulb ;
(TRPA1) prevents , release of (named) neurotransmitter /
influx of calcium ions ;
Explain the difference in the speed of conduction of an action potential along the length of a myelinated neurone and a non-myelinated neurone.
in myelinated neurones
1 conduction faster in myelinated neurone ; ora
2 depolarisation / action potential , can only occur
where (voltage-gated / Na(+)) channels present ;
3 idea that myelinated neurones have long(er) sections
with no, (voltage-gated / Na(+)) channels present ;
4 ion , movement / transfer ,
can only take place at the gaps / nodes ; ora
5 longer local circuits / fewer local circuits ;
6 saltatory conduction /
action potential jumps from node to node ; ora
suggest, with reasons, the effects that botulinum toxin may have once it has entered a neurone.
1 vesicle cannot fuse with cell membrane
and acetylcholine not secreted ;
2 protease / enzyme / toxin / it ,
hydrolyses ,
VAMP / SNARE / protein / peptide bonds ;
3 (because of hydrolysis)
VAMP (protein) cannot bind to SNARE (complex) ;
4 microtubules broken down so vesicle cannot move
towards membrane ;
State one way in which the nervous system decreases the heart rate.
impulses along parasympathetic nerve /
impulses along vagus nerve /
nerve endings releasing acetycholine ;
Describe and explain how the resting potential is established and how it is maintained in a sensory neurone.
pumping / active 1 sodium-potassium pump , uses ATP / uses energy / by active transport / (pumps) actively ; 2 pumps / actively moves , sodium ions / Na+ , out of , cell / axon / neurone , and , potassium ions / K+ , in ; passive / diffusing 3 K+ , diffuse / move / flow / leak , (freely) back out (of cell) ; 4 membrane less permeable to Na+ / fewer Na+ channels open , so fewer Na+ , diffuse / move / flow / leak , back in ; ora 5 voltage-gated (Na+) , channels closed ; 6 AVP ; QWC sodium-potassium pump, ion(s), diffuse (or derived term), permeable, voltage-gated
What term is used to refer to the value of −50 mV
threshold (potential / value / voltage) ;
Comment on the relationship between the strength of a stimulus, and the resulting action potential,
1 idea that only stimuli , that reach / are greater than ,
threshold value / -50mV ,
produce an action potential ; ora
2 (when stimulated) action potential either occurs or
does not / all-or-nothing (law) ;
3 idea that the action potential is the same
(magnitude / size) ,
no matter how strong the stimulus /
even if strength of stimulus increases ;
4 idea that a strong stimulus produces
many action potentials (in rapid succession) ;