Neuromuscular Flashcards
1
Q
Denervation changes
A
Angulated fiber - due to atrophy
Target fibers - created by denervation and reinnervation, with “bullseye” appearance
Small-group atrophy - denervation and reinnervation
Fiber type grouping - with reinnervation, a nerve branch may supply increasing # of fibers
Clumps of pyknotic nuclei - formed from long standing fiber atrophy
2
Q
Myopathic changes
A
Central nuclei - muscle dystrophies Necrosis of muscle Fiber size variation Fiber splitting Basophilic appearance of regenerating fibers Inflammatory reactions Muscle fibrosis Moth-eaten, whorled appearance of fibers
