Neurology - stroke Flashcards

1
Q

What are the signs and symptoms of anterior cerebral artery occlusion?

A
  • Contralateral hemiplegia
  • Gait apraxia
  • Severe apathy
  • Urinary incontinence
  • Lower limb sensory loss
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2
Q

What are the signs and symptoms of middle cerebral artery occlusion?

A
  • Contralateral hemiplegia
  • Contralateral homonymous hemianopia
  • Contralateral sensory loss
  • Dysarthria, dysphasia
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3
Q

What are the signs and symptoms of posterior cerebral artery occlusion?

A
  • Contralateral homonymous hemianopia +/- macular sparing
  • Contralateral hemiplegia
  • Ataxia/hemiballismus
  • Visual agnosia
  • Cortical blindness
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4
Q

What are the signs and symptoms of posterior inferior cerebellar artery occlusion?

A
  • Syncope
  • Vertigo
  • Hemiplegia
  • Dysarthria
  • Ipsilateral face numbness
  • Contralateral limb numbness
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5
Q

What are the signs and symptoms of basilar artery occlusion?

A

Dizziness
Vertigo
Diplopia
Dysarthria
Facial numbness
Ipsilateral hemiparesis

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6
Q

What are the criteria for a total anterior circulation stroke?

A

All three must be present

Unilateral weakness +/- sensory deficit of the face, arm and leg
Homonymous hemianopia
Higher cerebral dysfunction (dysphasia, visuospatial disorder)

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7
Q

What are the criteria for a partial anterior circulation stroke?

A

Two of:
* unilateral weakness +/- sensory deficit of the face, arm and leg
* homonymous hemianopia
* higher cerebral dysfunction (dysphasia, visuospatial disorder)

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8
Q

What are the criteria for lacunar syndrome (LACS)?

A

One of:
* pure sensory stroke
* pure motor stroke
* sensori-motor stroke
* ataxic hemiparesis

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9
Q

What are the criteria for posterior circulation syndrome (POCS)?

A

One of:
* cranial nerve palsy and a contralateral motor/sensory deficit
* bilateral motor/sensory deficit
* conjugate eye movement disorder e.g., gaze palsy
* cerebellar dysfunction e.g., ataxia, nystagmus, vertigo, dysarthria
* isolated homonymous hemianopia or cortical blindness

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10
Q

What is the difference between a TIA and a stroke?

A

Symptoms resolve within 24 hours

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11
Q

What is the management of TIA?

A

Aspirin 300mg immediately
Clopidogrel for stroke prophylaxis

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12
Q

What are the modifiable risk factors for stroke?

A

Atrial fibrillation (anticoagulated/not anticoagulated)
Smoker/drug use/alcohol
Dietary
Hypertension
Obesity
Hypercholesterolaemia
Oral contraceptive pill

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13
Q

What are the non-modifiable risk factors for stroke?

A

Ischaemic heart disease
Angina
Family history
Migraine
Diabetes mellitus
Previous stroke/CVA
Hyperthyroidism

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14
Q

What investigations should be performed for stroke?

A

Bloods: FBC, U&E, LFT, CRP, TFT, coag, lipid
Blood sugar
ECG
Imaging:
* CT head: may be normal, in ischaemic stroke hypodense in the region affected and vessel will be hyperdense
* Angiography
* MRI head
* carotid dopplers and echo if anterior circulation

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15
Q

When is endarterectomy indicated?

A

Indicated within 2 weeks if carotid stenosis is present and is:
* symptomatic
* 50-90% stenosis

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16
Q

How is the risk of further stroke calculated after a TIA?

A

Using ABCD2
A: Age >/= 60 years (1 point)
B: BP >/= 140/90 (1 point)
C: clinical features - unilateral weakness (2 points), speech impairment without weakness (1 point)
D: duration of symptoms - >/= 60 minutes (2 points), 10-59 minutes (1 point)
D: diabetes (1 point)

17
Q

When should thrombolysis be performed?

A

Within 4.5 hours of symptom onset

18
Q

When should thrombectomy be performed?

A

Within 6 hours of symptom onset

19
Q

What is the driving advice given after a TIA/stroke?

A

Must not drive for one month

20
Q

What is the management of haemorrhagic stroke?

A

Stop antiplatelet/anticoagulant/any drug that may increase risk of bleeding
Vitamin K/Beriplex for reverse anticoagulation
Aggressive BP control (<140 systolic)

21
Q

What are the features of cerebellar syndrome?

A

DANISH
Dysdiadochokinesis
Ataxia
Nystagmus
Intention tremor
Scanning speech, dysarthria
Hypotonia, hyporeflexia