Neurology SBAs Flashcards

1
Q

Scenario: A 3-year-old French Bulldog presents with a 2-week history of progressive paraparesis. Neurological examination reveals increased tone in the hindlimbs, with conscious proprioception and withdrawal reflexes present. Spinal reflexes are normal in the forelimbs. Where is the lesion most likely to be?

Options:

a) C1-C5
b) C6-T2
c) T3-L3
d) L4-S3
e) Sciatic nerve

A

Answer: c) T3-L3

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2
Q

Scenario: A 7-year-old Border Collie presents with a 1-week history of progressive hindlimb ataxia. The owners have noticed that the dog has become increasingly weak and struggles to jump onto furniture. Neurological examination reveals decreased conscious proprioception in both hindlimbs, with absent patellar reflexes. What is the most likely differential?

Options:

a) Atlantoaxial subluxation
b) Cauda equina syndrome
c) Cervical spondylomyelopathy
d) Degenerative myelopathy
e) Intervertebral disc disease

A

Answer: e) Intervertebral disc disease

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3
Q

Scenario: A 5-year-old Dachshund presents with acute onset paraparesis. The owners report that the dog was running in the garden when she suddenly yelped and collapsed. Neurological examination reveals absent voluntary motion, absent withdrawal reflexes, and absent deep pain in both hindlimbs. What is the most likely diagnosis?

Options:

a) Intervertebral disc disease with spinal cord transection
b) Fibrocartilaginous embolism
c) Spinal cord neoplasia
d) Meningomyelitis of unknown origin
e) Degenerative myelopathy

A

Answer: a) Intervertebral disc disease with spinal cord transection

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4
Q

Scenario: A 9-year-old German Shepherd Dog presents with a 3-month history of progressive hindlimb ataxia. The owners report that the dog has difficulty walking and often stumbles. Neurological examination reveals decreased conscious proprioception in both hindlimbs, with increased tone and hyperreflexia. What is the most appropriate diagnostic test to perform next?

Options:

a) MRI
b) Radiography
c) CSF analysis
d) Myelography
e) CT scan

A

Answer: a) MRI

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5
Q

Scenario: A 4-year-old Staffordshire Bull Terrier presents with a 2-week history of progressive tetraparesis. The owners report that the dog is weak and stumbles frequently. Neurological examination reveals decreased conscious proprioception in all four limbs, with increased tone and hyperreflexia. What is the most likely diagnosis?

Options:

a) Cervical spondylomyelopathy
b) Degenerative myelopathy
c) Intervertebral disc disease
d) Meningomyelitis of unknown origin
e) Fibrocartilaginous embolism

A

Answer: a) Cervical spondylomyelopathy

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6
Q

Scenario: A 6-month-old Chihuahua presents with acute onset tetraparesis. The owners report that the dog was playing with a child when it suddenly yelped and collapsed. Neurological examination reveals decreased conscious proprioception in all four limbs, with absent withdrawal reflexes and decreased tone. What is the most likely diagnosis?

Options:

a) Atlantoaxial subluxation
b) Cervical spondylomyelopathy
c) Intervertebral disc disease
d) Meningomyelitis of unknown origin
e) Fibrocartilaginous embolism

A

Answer: a) Atlantoaxial subluxation

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7
Q

Scenario: A 2-year-old cat presents with acute onset non-ambulatory paraparesis. The owners report that the cat was fine yesterday but is now unable to use its hind legs. Neurological examination reveals increased tone in the hindlimbs, with intact withdrawal reflexes and pain sensation. What is the most likely diagnosis?

Options:

a) Aortic thromboembolism
b) Fibrocartilaginous embolism
c) Spinal cord neoplasia
d) Trauma
e) Meningomyelitis

A

Answer: a) Aortic thromboembolism

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8
Q

Scenario: A 10-year-old Labrador Retriever presents with a 2-day history of progressive tetraparesis. The owners report that the dog is weak and stumbles frequently. Neurological examination reveals decreased conscious proprioception in all four limbs, with increased tone and hyperreflexia. What is the most appropriate diagnostic test to perform next?

Options:

a) MRI
b) Radiography
c) CSF analysis
d) Myelography
e) CT scan

A

Answer: a) MRI

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9
Q

Scenario: A 6-year-old French Bulldog presents with a 2-month history of progressive generalized seizures. The seizures are now occurring 3 times per day and last for approximately 3 minutes each. The dog is dull and ataxic between seizures. Neurological examination reveals a left-sided head tilt, spontaneous nystagmus, and reduced mentation. What is the most likely cause of the seizures?

Options:

a) Idiopathic epilepsy
b) Hepatic encephalopathy
c) Meningoencephalitis of unknown origin
d) Intracranial neoplasia
e) Trauma

A

Answer: b) Hepatic encephalopathy

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10
Q

SBA 65

Scenario: A 2-year-old Golden Retriever presents with a sudden onset of seizures. The dog has had 1 seizure per week for the past 3 weeks. The dog is reported to be normal between seizures. Neurological examination is unremarkable. What is the most appropriate treatment?

Options:

a) Phenobarbital IV
b) Imepitoin PO
c) Potassium bromide PO
d) Levetiracetam PO
e) Zonisamide PO

A

Answer: b) Imepitoin

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11
Q

Scenario: A 10-year-old Domestic Shorthair cat presents with a 3-month history of progressive seizures. The seizures are now occurring every 2 weeks. The cat is normal between seizures. Neurological examination reveals reduced conscious proprioception in the right forelimb and hindlimb, reduced vision in the right eye, and circling to the left. What is the most likely cause of the seizures?

Options:

a) Idiopathic epilepsy
b) Hepatic encephalopathy
c) Meningoencephalitis of unknown origin
d) Intracranial neoplasia
e) Trauma

A

Answer: d) Intracranial neoplasia

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12
Q

SBA 67

Scenario: An 8-year-old Jack Russell Terrier presents with sudden onset seizures. The dog has had 5 generalized tonic-clonic seizures in the past 2 hours, each lasting approximately 3 minutes. The seizures started 1 hour after strenuous exercise. On examination, the dog is laterally recumbent with episodes of opisthotonos. What is the most appropriate immediate treatment?

Options:

a) Diazepam 0.5 mg/kg intravenously
b) Phenobarbital 4 mg/kg intravenously
c) Levetiracetam 60 mg/kg intravenously
d) Imepitoin 30 mg/kg orally
e) Potassium bromide 40 mg/kg orally

A

Answer: a) Diazepam 0.5 mg/kg intravenously

Explanation: This dog is experiencing cluster seizures, which are a medical emergency. Diazepam administered intravenously is the most appropriate treatment for rapid seizure control. It has a fast onset of action and is effective in terminating seizures.

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13
Q

Scenario: A 5-year-old male neutered Border Collie presents with a 1-week history of progressive ataxia and weakness. The owners report that the dog is stumbling and has difficulty climbing stairs. Neurological examination reveals decreased conscious proprioception in all four limbs, with increased tone and hyperreflexia in the hindlimbs. What is the most likely diagnosis?

Options:

a) Cervical spondylomyelopathy
b) Degenerative myelopathy
c) Intervertebral disc disease
d) Meningomyelitis of unknown origin
e) Fibrocartilaginous embolism

A

Answer: a) Cervical spondylomyelopathy

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14
Q

Scenario: A 4-year-old Border Collie is presented to you with ongoing status epilepticus. The dog has received 3 rounds of 1mg/kg diazepam intravenously 10 minutes apart with no improvement. The seizures consist of tonic-clonic activity with paddling of all four limbs, hypersalivation, and loss of bladder and bowel continence. What is the most appropriate treatment to administer now?

Options:

a) Levetiracetam 60mg/kg intravenously
b) Midazolam 0.2mg/kg intravenously, followed by a constant rate infusion of 1mg/kg/hour
c) Phenobarbital 15mg/kg PO
d) Propofol 4mg/kg intravenously as a bolus, followed by a constant rate infusion at 0.4mg/kg/min
e) Atipamezole 50mcg/kg intramuscularly

A

Answer: D

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15
Q

Scenario: A 9-year-old male neutered West Highland White Terrier presents with a 1-month history of circling to the right, a left head tilt, and nystagmus with the fast phase to the right. Neurological examination reveals no other abnormalities. Which of the following is the most likely diagnosis?

Options:

a) Otitis media/interna
b) Idiopathic vestibular syndrome
c) Cerebellar neoplasia
d) Brainstem neoplasia
e) Thalamic infarct

Answer: a) Otitis media/interna

A

Answer: a) Otitis media/interna.

Explanation: While idiopathic vestibular syndrome is common in older dogs, this dog has a chronic history (1 month) which makes otitis media/interna more likely.

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16
Q

Scenario: A 4-year-old female entire Labrador Retriever presents with a 2-week history of progressive pelvic limb weakness and ataxia. Neurological examination reveals paraparesis with increased tone and hyperreflexia in the pelvic limbs. Conscious proprioception is reduced in both pelvic limbs. Thoracic limb reflexes are normal. Where is the lesion most likely to be?

Options:

a) C1-C5
b) C6-T2
c) T3-L3
d) L4-S3
e) Neuromuscular junction

A

Answer: c) T3-L3

Explanation: The clinical signs localize to the T3-L3 spinal cord segments. Increased tone and hyperreflexia indicate an upper motor neuron lesion.

17
Q

Scenario: A 12-year-old male neutered Shih Tzu presents with a 6-month history of generalized seizures. The seizures are characterized by tonic-clonic activity with paddling of all four limbs, hypersalivation, and loss of bladder and bowel continence. The seizures occur approximately once a month and last for around 2 minutes. The dog is reported to be normal between seizures. Neurological examination is unremarkable. What is the most appropriate treatment to administer?

Options:

a) Diazepam 0.5mg/kg intravenously
b) Imepitoin 10mg/kg orally twice daily
c) Levetiracetam 20mg/kg orally three times daily
d) Phenobarbital 2mg/kg orally twice daily
e) Potassium bromide 30mg/kg orally once daily

A

Answer: b) Imepitoin 10mg/kg orally twice daily

Explanation: Imepitoin is a good first-line anti-seizure medication for dogs with infrequent seizures and no other neurological abnormalities. It is generally well-tolerated and has a good safety profile.

18
Q

Scenario: A 7-year-old male neutered Domestic Shorthair cat presents with a 2-day history of non-ambulatory tetraparesis. The owners report that the cat was previously healthy but suddenly became unable to use all four limbs. Neurological examination reveals decreased conscious proprioception in all four limbs, with absent withdrawal reflexes and decreased tone. What is the most likely diagnosis?

Options:

a) Aortic thromboembolism
b) Cervical spondylomyelopathy
c) Intervertebral disc disease
d) Meningomyelitis of unknown origin
e) Trauma

A

Answer: a) Aortic thromboembolism

Explanation: Acute onset non-ambulatory tetraparesis with absent withdrawal reflexes and decreased tone in all four limbs is a classic presentation of aortic thromboembolism in cats.

19
Q

Scenario: A 3-year-old female entire Cavalier King Charles Spaniel presents with a 1-month history of intermittent scratching at the neck and shoulders. The owners report that the dog appears to be painful during these episodes. Neurological examination is unremarkable. What is the most likely diagnosis?

Options:

a) Chiari-like malformation/syringomyelia
b) Cervical spondylomyelopathy
c) Idiopathic epilepsy
d) Meningoencephalitis of unknown origin
e) Otitis media/interna

A

Answer: a) Chiari-like malformation/syringomyelia

Explanation: Intermittent scratching at the neck and shoulders, often described as “phantom scratching,” is a common clinical sign in dogs with Chiari-like malformation and syringomyelia.

20
Q

Scenario: A 9-year-old male neutered Boxer presents with a 2-week history of progressive right hindlimb lameness. The owners report that the dog is reluctant to walk and has difficulty jumping onto furniture. Neurological examination reveals right hindlimb monoparesis with decreased conscious proprioception and absent patellar reflex. What is the most likely diagnosis?

Options:

a) Cauda equina syndrome
b) Degenerative myelopathy
c) Fibrocartilaginous embolism
d) Lumbosacral discospondylitis
e) Sciatic nerve injury

A

Answer: d) Lumbosacral discospondylitis

Explanation: Lumbosacral discospondylitis is an infection of the intervertebral disc and adjacent vertebrae. It can cause pain and neurological deficits in the hindlimbs, as seen in this case.

21
Q

Scenario: A 5-year-old male entire Staffordshire Bull Terrier presents with a 3-month history of progressive tetraparesis. The owners report that the dog is weak and stumbles frequently. Neurological examination reveals decreased conscious proprioception in all four limbs, with increased tone and hyperreflexia. What is the most likely diagnosis?

Options:

a) Cervical spondylomyelopathy
b) Degenerative myelopathy
c) Intervertebral disc disease
d) Meningomyelitis of unknown origin
e) Trauma

A

Answer: a) Cervical spondylomyelopathy

Explanation: Cervical spondylomyelopathy, or “wobbler syndrome,” is a common cause of progressive tetraparesis in large breed dogs. It is caused by compression of the spinal cord in the neck.

22
Q

Scenario: A 10-year-old female neutered Domestic Shorthair cat presents with a 1-week history of circling to the left, right head tilt, and facial paralysis. Neurological examination reveals no other abnormalities. What is the most likely diagnosis?

Options:

a) Feline idiopathic vestibular syndrome
b) Cerebellar hypoplasia
c) Nasopharyngeal polyp
d) Otitis media/interna
e) Thiamine deficiency

A

Answer: a) Feline idiopathic vestibular syndrome

Explanation: Feline idiopathic vestibular syndrome is a common cause of acute onset vestibular signs in cats. It is typically self-limiting and resolves within a few weeks.

23
Q

Scenario: A 6-year-old male neutered Greyhound presents with a 2-day history of acute onset non-ambulatory paraparesis. The owners report that the dog was running in the park when he suddenly yelped and collapsed. Neurological examination reveals absent voluntary motion, absent withdrawal reflexes, and absent deep pain in both hindlimbs. What is the most likely diagnosis?

Options:

a) Intervertebral disc disease with spinal cord transection
b) Fibrocartilaginous embolism
c) Spinal cord neoplasia
d) Trauma
e) Aortic thromboembolism

A

Answer: a) Intervertebral disc disease with spinal cord transection

Explanation: Acute onset non-ambulatory paraparesis with absent deep pain suggests a severe spinal cord injury, such as that caused by intervertebral disc extrusion with spinal cord transection.

24
Q

Scenario: A 2-year-old male neutered Border Collie presents with a 1-month history of episodic weakness and collapse. The episodes occur several times a week and last for a few minutes. The dog is reported to be normal between episodes. Neurological examination is unremarkable. What is the most appropriate diagnostic test to perform next?

Options:

a) MRI of the brain
b) CSF analysis
c) Blood glucose and insulin levels
d) ACTH stimulation test
e) Bile acids stimulation test

A

Answer: c) Blood glucose and insulin levels

Explanation: Episodic weakness and collapse can be a sign of hypoglycaemia, which can be caused by insulinoma (a tumour of the pancreas that secretes insulin). Measuring blood glucose and insulin levels is the most appropriate next step to investigate this possibility.

25
Q

Scenario: A 8-year-old female spayed Jack Russell Terrier presents with a 2-year history of progressive hindlimb ataxia. The owners report that the dog has difficulty walking and often stumbles. Neurological examination reveals decreased conscious proprioception in both hindlimbs, with increased tone and hyperreflexia. What is the most likely diagnosis?

Options:

a) Degenerative myelopathy
b) Cervical spondylomyelopathy
c) Intervertebral disc disease
d) Lumbosacral disease
e) Meningomyelitis of unknown origin

A

Answer: d) Lumbosacral disease

26
Q

Scenario: A 7-year-old male neutered Border Collie presents with a 2-week history of generalized seizures. The seizures occur approximately 3 times per day and last for around 2 minutes. The dog is reported to be normal between seizures. Neurological examination is unremarkable.

Lead-in: What is the most appropriate treatment to administer?

Options:

a) Diazepam 0.5mg/kg intravenously
b) Imepitoin 10mg/kg orally twice daily
c) Levetiracetam 20mg/kg orally three times daily
d) Phenobarbital 2mg/kg orally twice daily
e) Potassium bromide 30mg/kg orally once daily

A

Answer: d) Phenobarbital 2mg/kg orally twice daily

Explanation: Phenobarbital is the only licenced medicine for cluster seizures.

27
Q

A 6-year-old French Bulldog presents with a right head tilt, circling to the right, and nystagmus with the fast phase to the right. The lesion is most likely located in the_________________________________.

A

right peripheral vestibular system.

28
Q

A 4-year-old Dachshund presents with paraparesis and increased tone in the pelvic limbs. The lesion is most likely located between _________

A

T3-L3

29
Q

A 10-year-old Labrador Retriever presents with seizures, dullness, and a left head tilt. The lesion is most likely located in the __________ and ___________

A

forebrain and brainstem.

30
Q

A 2-year-old cat presents with acute onset non-ambulatory paraparesis and spinal pain. The lesion is most likely located in the______________________.

A

T3-L3 spinal cord

31
Q

A 5-year-old Staffordshire Bull Terrier presents with progressive tetraparesis and ataxia. The lesion is most likely located in the__________________________________

A

cervical spinal cord (C1-C8).

32
Q

A 9-year-old German Shepherd Dog presents with pelvic limb ataxia and conscious proprioceptive deficits. The lesion is most likely located in the_______________________

A

T3-L3 spinal cord segments or L4-S3 spinal cord segments.

33
Q

A 8-year-old cat presents with a 1-week history of progressive tetraparesis. Initially, only the pelvic limbs were affected, but now the thoracic limbs are also showing signs of weakness. The lesion is most likely located in the_________________________.

A

Multifocal spinal cord (C6-T2 and T3-L3) or is a generalized neuromuscular disease.

34
Q

A 9-month-old Chihuahua presents with acute onset non-ambulatory tetraparesis and neck pain. Neurological examination reveals normal proprioception and reflexes in all four limbs. The lesion is most likely located in the_________________.

A

cervical spinal cord (C1-C5).

35
Q

Scenario: A 3-year-old Cavalier King Charles Spaniel presents with cluster seizures. The dog has had three generalized tonic-clonic seizures in the past hour, each lasting approximately 2 minutes. The dog is still actively seizing on presentation. Your practice has no diazepam. What is the most appropriate treatment?

Options:

a) Levetiracetam 60 mg/kg intravenously
b) Phenobarbital 15 mg/kg intravenously
c) Midazolam 0.2 mg/kg intravenously
d) Potassium bromide 40 mg/kg orally
e) Imepitoin 30 mg/kg orally

A

Answer: c) Midazolam 0.2 mg/kg intravenously