Neurology & Psychiatry Flashcards
Dementia, Depression, Altered Mental Status, Syncope, SUD
What is the mnemonic for syncope causes?
HEAD: Hypoxia, Epilepsy, Anxiety, Dysautonomia
HEART: Heart disease, Embolism, Aortic stenosis, Rhythm abnormality, Tachycardia/bradycardia.
How is syncope evaluated (4)?
- Orthostatics
- ECG
- Holter monitor
- echo (if structural heart disease suspected)
What is the treatment for vasovagal syncope (3)?
- Reassurance
- hydration
- beta-blockers (if recurrent)
- If they ask for the most ACCURATE test for Alzheimer →
- Test for clinical diagnosis →
- Brain biopsy
- MRI
Dementia tx
- Mild-to-Moderate Dementia → Acetylcholinesterase inhibitors (Donepezil, Rivastigmine, Galantamine)
- Moderate-to-Severe Dementia → NMDA receptor antagonist (Memantine)
Workup for dementia (5)
- MMSE (Mini-Mental Status Exam) → Quick screening
- MoCA (Montreal Cognitive Assessment) → More sensitive for early dementia
- Neuroimaging (CT/MRI) → Rule out reversible causes (normal pressure hydrocephalus, tumors, strokes)
- B12 & TSH → Rule out metabolic causes
- RPR → Rule out neurosyphilis
What are the items on the SAD PERSONS suicide risk factors?
When would you treat a patient indefinitely for major depression?
If patient had ≥3 major depressive episodes
(first episode = tx for 6 months)
first line depression tx
- fluoxetine
- sertraline
- venlafaxine
SUD evaluation
- CAGE questions
- UA tox screen
tx for opioid use disorder
tx for alcohol use disorder
- Opioid Use Disorder → Methadone or Buprenorphine/Naloxone (Suboxone)
- Alcohol Use Disorder → Naltrexone (first-line), Disulfiram (second-line, for abstinent patients)
Prognosis: SUD
Relapse is common → Best outcomes with long-term therapy (MAT, therapy, social support)
timeline of alcohol w/d
- 6-12 hours: tremor, HA, anxiety
- 12-48 hours: seizure
- 48-96 hours: DTs (hallucination, fever, autonomic instability)
delirium tremens tx
IV benzos
Ddx for altered mental status (AMS)
AEIOU TIPS mnemonic
Alcohol
Electrolytes
Infection
Overdose
Uremia
Trauma
Insulin
Poisoning
Stroke
If a comatose patient is found down, give …
“Coma Cocktail” = Dextrose (Glucose), Thiamine, Naloxone!