Neurology histology Flashcards
What is the nervous system divided into?
- Central nervous system
- brain and the spinal cord - Peripheral nervous system
- nerve fibres and nerve ganglia
what is the two groups of cells in nerve tissues?
- neurons (impulse conducting cells)
- neuroglia (non-neuronal support cells)
What are the non-neuronal support cells in PNS and CNS respectively?
- PNS: schwann cells/ satellite cells
- CNS: oligodendrocytes/ microgial cells/ astrocytes/ ependymal cells
what is the functions of regional neurons?
- Dendrites: input region
- Cell body: nurtures the cell
- Axon: conducts excitation
4: Telodendric zone: output region
what is schwann cell?
one inter-node of neurilemma
what is the node of Ranvier?
the unmyelinated part between each inter-node
what are the 3 morphological classification of neurons?
- unipolar: sensory neurons where cell body sits to the side
- bipolar: sensory neurons where cell body sits inside the axon.
- Multipolar: motor and sensory neurons
what are the functional classification of neurons?
- Sensory neuron
- Motor neurons
- Interneurons
what are the functions of neuroglia in CNS?
supportive functions include:
1. nourishment
- physical support for neuroonal processes
- electrical insulation (myelin)
- maintain extracellular environment
- Phagocytosis (remove of debris)
Describe astrocytes (A).
- largest glial cell
- plentiful processes extend between neurons and blood vessels
- promote tight junctions to form blood-brain barrier
- structural support
- regulate extracellular brain fluid composition
- immune function
Describe oliogodendrocytes.
- myelinate several axons
- each oligodendrocyte process wraps around one axon at several sites or several axons.
Describe microglial cells.
- phagosytosis
- small with elongated nucleus
- short, twisted processes
Describe ependymal cells.
- columnar or cuboidal epithelial-like cells with motile cilia that line the ventricles of the brain and central canal of the spinal cord
- modified ependymal cells form part of choroid plexus (make CSF)
what are the functions of neuroglia in PNS (schwann cells / satellite cells)?
- provide protective environment for neurons
- Proliferate and become phagocytic when there is nerve damage
where do schwann cells locate at?
surround axons (myelinating and non-myelinatin)