Female anatomy and histology Flashcards
What is the function of ovary?
- development and maturation female gemr cells
- production of reproductive hormones
Describe the structure of the ovary.
- mesovarium
- part of the supportive apparatus - germinal epithelium
- simple cuboidal epithelium
- continuous with serosal epithelium of the peritoneum - tunica albuginea
- cortex
- connective tissue enclosing follicles and corpus luteum/corpora lutea - medulla
- loose connective tissue containing blood and lymph vessels, nerves
Where can the ovarian follicles (primary oocyte & follicular cells) be found?
cortex
State the stages of the development of follicles in the cortex.
- Primordial follicle
- Primary follicle
- Secondary follicle
- Tertiary follicle
- Mature follicle
- Corpora lutea
Describe primordial follicles
- primary oocyte and single layer of flattened follicular cells
- “resting” follicles
- form prenatally
Describe primary follicles.
- primary oocyte surrounded by simple cuboidal follicular cells
- slight increase in size
Describe Secondary follicles.
- primary oocyte surrounded by at lease 2 layers of cuboidal to columnar follicular cells
- changes from follicular cells to granulosa
- substantial increase in size
- differentiation of stromal cells into theca follicularis
development of zona pellucida (protein layer)
Describe tertiary follicles.
- presence of large, fluid filled cavity (antrum)
- follicular cells differentiate into basal cells/ intermediate cells and granulosa cells
- development of cumulus oophorus
- stratification of theca follicularis
How does corpus luteum form?
At ovulation > follicle ruptures > corpus hemorrhagicum
- blood clots form in antruym due to rupture of vessels
What is the structure of tubular organ?
- Tunica mucosa
- epithelium
- lamina propria - Tela submucosa
- Tunica muscularis
- Tunica serosa/ adventitia
Describe the layers of uterine tube.
- Tunica mucosa/ sub-mucosa
- Epithelium: simple to pseudostratified columnar epithelium
- Ciliated and non ciliated cells (peg-cells)
- non-ciliated: mucus secreting cells
- microvilli on both ciliated and non-ciliated cells - Tunica muscularis
- inner circular/ outer longitudinal
- thinner cranially and thicker caudally (isthmus) - Tunica serosa
- Lies within mesoalpinx (extension part of broad ligament)
- Lies in the abdominal cavity
- Broad ligament also attaches to these structures
What is 3 structures of uterus ?
body (corpus), body (cornua) and cervix
State the 3 layers that the uterus consist of.
- Endometrium (tunica mucosa/ submucosa)
- strata functionalis
- strata basalis - Myometrium (tunica muscularis)
- inner circular
- vascular layer
- outer longitudinal layer - Perimetrium (tunica serosa)
Describe endometrium of uterus.
- Stratum functionalis (functional zone/ layer)
- degenerates after pregnancy/ oestrus
- surface epithelium (simple columnar to pseudostratified )
- subepithelial part: loose connective tissue, simple coiled tubular uterine glands, growth stimulated by oestrogen - Stratum basalis (basal zone/ layer)
- persists throughout
- functional zone restored from this layer (faces luminal side)
- uterine glands: stimulated by oestrogen > increase the thickness of layer as gland is active
Describe the myometrium of the uterus.
- smooth muscle fibre bundles
- thick inner layer (circular)
- outer longitudinal layer
- vascular layer in between
- fibres of the out layer extend into broad ligament
Describe the layer of cervix.
- Tunica mucosa/ submucosa
- highly folded
- no uterine glands
- simple columnar epithelium with goblet cells (gland cells/ only embedded on the surface of epithelium/ mucus produced changes depending on the cycle)
- extensive venous supply - Tunica muscularis
- very thick inner circular layer (with elastic fibres for pregnancy)
- less developed outer, longitudinal layer - Tunica serosa
Describe the layer in Vagina/ Vestibule
- Tunica mucosa/ submucosa
- stratified squamous epithelium > undergoes cyclic changes
- lymphoid nodules
- fold reduce lumen
- vestibule glands (branched, tubular, mucous glands) - Tunica muscularis
- 2 layers
- Inner circular and outer longitudinal - Tunica serosa
- only present in cranial part
- mostly retroperitoneal > adventitia
What is mammary gland composed of?
- glandular tissue
- connective tissue septa
Mammary complex structures
Alveolus > lobules > lobe
What is the milk pathway in mammary complex structure?
Small excretory passages (intralobular ducts) > interlobular ducts > Lactiferous ducts (large milk ducts) > Lactiferous sinus > teat canal
Describe alveolus histologically.
- secretory part
- simple cuboidal epithelium
- columnar when active - myoepithelial cells
- with contractile properties
- sits between the actual cell and the basal membrane
- contraction of myoepithelial cells > milk flow
What is the 3 structures that consist in the teat?
- teat wall
- smooth muscle cells (longitudinal and circular; form a sphincter around teat canal
- network of collagen and elastic fibres - teat sinus
- bi-layered cuboidal - papillary duct
- short narrow canal
- with transition: change to keratinized stratified epithelium
- longitudinal folds
- circular smooth muscle > sphincter
State the steps of parental mamogenesis.
Mammary ridge > primary mammary bud > Secondary mammary bud > canalization
Describe mammary ridge.
mammary ridges are thickened epidermal tissue (mammary crest) that give rise to the mammary gland.
Describe primary mammary bud.
The thickened epidermal tissue begins to develop inward and penetrate into the mesenchyme (dermis).
Describe secondary mammary bud.
the primary mammary bud begins to send out branches that further penetrate into the dermis.
Describe canalization.
- Finger-like secondary buds begin to lengthen and branch out.
- Finally they begin to form canals or channels (canalisation) that will form the duct system of the gland.
- myoepithelial cells surround the terminal portions of the developing gland.
Describe 1st pregnancy
- progesterone affect secretory unit (alveoli)
- oestrogen affect duct development
- placenta send out hormone > influence mammary gland
What does each mammary gland consist of?
each mammary gland consists of:
1. glandular tissue
2. fatty infiltrates
What does teat consist of?
- dense connective tissue
- smooth muscle (longitudinal)
- Vessels and lymphatics
- epidermis of teat (hairless and non-glandular)
What makes the teat hold on to milk?
Circular muscular ring
What does the udder consist of?
- lateral lamina
- fibrous connective tissues arise dorsal laterally to the external inguinal ring, and expand cranially to enfold the entire lateral surfaces of udder. - medial lamina
- secondary lamina
- allows udder to expand - intermammary groove
- between left and right
- no groove between front and back
Describe the arterial supply in cow (and mare).
External pudendal > cranial mammary a / caudal mammary a. > medial mammary
What is the venous drainage for cow?
- External pudendal v
- Subcutaneous abdominal (milk) vein
- Ventral vein (smaller, hind quarter)
Broad ligament is divided into 3 parts:
- Mesovarium
- Mesosalpinx
- Mesometrium