Female anatomy and histology Flashcards

1
Q

What is the function of ovary?

A
  1. development and maturation female gemr cells
  2. production of reproductive hormones
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe the structure of the ovary.

A
  1. mesovarium
    - part of the supportive apparatus
  2. germinal epithelium
    - simple cuboidal epithelium
    - continuous with serosal epithelium of the peritoneum
  3. tunica albuginea
  4. cortex
    - connective tissue enclosing follicles and corpus luteum/corpora lutea
  5. medulla
    - loose connective tissue containing blood and lymph vessels, nerves
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where can the ovarian follicles (primary oocyte & follicular cells) be found?

A

cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

State the stages of the development of follicles in the cortex.

A
  1. Primordial follicle
  2. Primary follicle
  3. Secondary follicle
  4. Tertiary follicle
  5. Mature follicle
  6. Corpora lutea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe primordial follicles

A
  • primary oocyte and single layer of flattened follicular cells
  • “resting” follicles
  • form prenatally
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe primary follicles.

A
  • primary oocyte surrounded by simple cuboidal follicular cells
  • slight increase in size
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe Secondary follicles.

A
  • primary oocyte surrounded by at lease 2 layers of cuboidal to columnar follicular cells
  • changes from follicular cells to granulosa
  • substantial increase in size
  • differentiation of stromal cells into theca follicularis
    development of zona pellucida (protein layer)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe tertiary follicles.

A
  • presence of large, fluid filled cavity (antrum)
  • follicular cells differentiate into basal cells/ intermediate cells and granulosa cells
  • development of cumulus oophorus
  • stratification of theca follicularis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does corpus luteum form?

A

At ovulation > follicle ruptures > corpus hemorrhagicum

  • blood clots form in antruym due to rupture of vessels
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the structure of tubular organ?

A
  1. Tunica mucosa
    - epithelium
    - lamina propria
  2. Tela submucosa
  3. Tunica muscularis
  4. Tunica serosa/ adventitia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe the layers of uterine tube.

A
  1. Tunica mucosa/ sub-mucosa
    - Epithelium: simple to pseudostratified columnar epithelium
    - Ciliated and non ciliated cells (peg-cells)
    - non-ciliated: mucus secreting cells
    - microvilli on both ciliated and non-ciliated cells
  2. Tunica muscularis
    - inner circular/ outer longitudinal
    - thinner cranially and thicker caudally (isthmus)
  3. Tunica serosa
    - Lies within mesoalpinx (extension part of broad ligament)
    - Lies in the abdominal cavity
    - Broad ligament also attaches to these structures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is 3 structures of uterus ?

A

body (corpus), body (cornua) and cervix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

State the 3 layers that the uterus consist of.

A
  1. Endometrium (tunica mucosa/ submucosa)
    - strata functionalis
    - strata basalis
  2. Myometrium (tunica muscularis)
    - inner circular
    - vascular layer
    - outer longitudinal layer
  3. Perimetrium (tunica serosa)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe endometrium of uterus.

A
  1. Stratum functionalis (functional zone/ layer)
    - degenerates after pregnancy/ oestrus
    - surface epithelium (simple columnar to pseudostratified )
    - subepithelial part: loose connective tissue, simple coiled tubular uterine glands, growth stimulated by oestrogen
  2. Stratum basalis (basal zone/ layer)
    - persists throughout
    - functional zone restored from this layer (faces luminal side)
    - uterine glands: stimulated by oestrogen > increase the thickness of layer as gland is active
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Describe the myometrium of the uterus.

A
  • smooth muscle fibre bundles
  • thick inner layer (circular)
  • outer longitudinal layer
  • vascular layer in between
  • fibres of the out layer extend into broad ligament
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe the layer of cervix.

A
  1. Tunica mucosa/ submucosa
    - highly folded
    - no uterine glands
    - simple columnar epithelium with goblet cells (gland cells/ only embedded on the surface of epithelium/ mucus produced changes depending on the cycle)
    - extensive venous supply
  2. Tunica muscularis
    - very thick inner circular layer (with elastic fibres for pregnancy)
    - less developed outer, longitudinal layer
  3. Tunica serosa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe the layer in Vagina/ Vestibule

A
  1. Tunica mucosa/ submucosa
    - stratified squamous epithelium > undergoes cyclic changes
    - lymphoid nodules
    - fold reduce lumen
    - vestibule glands (branched, tubular, mucous glands)
  2. Tunica muscularis
    - 2 layers
    - Inner circular and outer longitudinal
  3. Tunica serosa
    - only present in cranial part
    - mostly retroperitoneal > adventitia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is mammary gland composed of?

A
  1. glandular tissue
  2. connective tissue septa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Mammary complex structures

A

Alveolus > lobules > lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the milk pathway in mammary complex structure?

A

Small excretory passages (intralobular ducts) > interlobular ducts > Lactiferous ducts (large milk ducts) > Lactiferous sinus > teat canal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Describe alveolus histologically.

A
  1. secretory part
    - simple cuboidal epithelium
    - columnar when active
  2. myoepithelial cells
    - with contractile properties
    - sits between the actual cell and the basal membrane
    - contraction of myoepithelial cells > milk flow
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the 3 structures that consist in the teat?

A
  1. teat wall
    - smooth muscle cells (longitudinal and circular; form a sphincter around teat canal
    - network of collagen and elastic fibres
  2. teat sinus
    - bi-layered cuboidal
  3. papillary duct
    - short narrow canal
    - with transition: change to keratinized stratified epithelium
    - longitudinal folds
    - circular smooth muscle > sphincter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

State the steps of parental mamogenesis.

A

Mammary ridge > primary mammary bud > Secondary mammary bud > canalization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Describe mammary ridge.

A

mammary ridges are thickened epidermal tissue (mammary crest) that give rise to the mammary gland.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Describe primary mammary bud.
The thickened epidermal tissue begins to develop inward and penetrate into the mesenchyme (dermis).
26
Describe secondary mammary bud.
the primary mammary bud begins to send out branches that further penetrate into the dermis.
27
Describe canalization.
1. Finger-like secondary buds begin to lengthen and branch out. 2. Finally they begin to form canals or channels (canalisation) that will form the duct system of the gland. 3. myoepithelial cells surround the terminal portions of the developing gland.
28
Describe 1st pregnancy
- progesterone affect secretory unit (alveoli) - oestrogen affect duct development - placenta send out hormone > influence mammary gland
29
What does each mammary gland consist of?
each mammary gland consists of: 1. glandular tissue 2. fatty infiltrates
30
What does teat consist of?
1. dense connective tissue 2. smooth muscle (longitudinal) 3. Vessels and lymphatics 4. epidermis of teat (hairless and non-glandular)
31
What makes the teat hold on to milk?
Circular muscular ring
32
What does the udder consist of?
1. lateral lamina - fibrous connective tissues arise dorsal laterally to the external inguinal ring, and expand cranially to enfold the entire lateral surfaces of udder. 2. medial lamina 3. secondary lamina - allows udder to expand 4. intermammary groove - between left and right - no groove between front and back
33
Describe the arterial supply in cow (and mare).
External pudendal > cranial mammary a / caudal mammary a. > medial mammary
34
What is the venous drainage for cow?
1. External pudendal v 2. Subcutaneous abdominal (milk) vein 3. Ventral vein (smaller, hind quarter)
35
Broad ligament is divided into 3 parts:
1. Mesovarium 2. Mesosalpinx 3. Mesometrium
36
Female tract differentiation. What will the following structure differentiate into? (i) Urogenital sinus (ii) caudal portion urogenital sinus (iii)Genital tubercle (iv) Urogenital folds
(i) caudal vagina (ii) vestibule (iii)clitoris (F)/ penis (M) (iv) labia of vulva (F)
37
Define proper ligament.
attaches the uterine end of the ovary to the cranial end of the uterine horn
38
Define suspensory ligament.
- attached cranially to the middle and ventral of the last one or two ribs - caudally attaches to ventral aspect of ovary and mesosalpinx, lying between the opening of the ovarian bursa and ascending uterine tube.
39
Define round ligament.
attaches the uterus and ovary to the body wall.
40
Define mesovarium.
attaches the ovary to the dorsolateral region of the abdominal wall.
41
Define mesosalpinx.
- encloses the ovary in a pouches called ovarian bursa. -curves around the dorsal and ventrolateral borders of the ovary to attach to the medial surface of the broad ligament just dorsal to the ovary - Entire uterine tube, ascending and descending, lies within the peritoneal layers of the mesosalpinx
42
Define mesometrium.
- begins at the cranial edge of the uterine horn and extends caudally to bladder and colon.
43
What is the ruminant ligament that add stability to uterine horn?
Cornual ligament
44
Ovary position
between kidney and pelvic inlet
45
What is UTJ
utero-tubal junction- junction between uterine tube and uterine horn
46
Follicle stages.
Primordial follicles > primary follicles > secondary follicle > tertiary follicle (antral follicle) > ovulating follicle > corpus luteum (yellow) > corpus albicans (white)
47
What is the function of vagina?
- female copulatory organ - birth canal - site of semen deposition (bitch, queen, cow, rabbit & women)
48
What is internal ostium?
opening of cervix into body of uterus
49
What is external ostium?
opening of cervix into vagina
50
What is fornix
spca between protruding cervix and the vaginal wall
51
What is vestibule?
1. continuation of vagina 2. shorter than vagina 3. slopes caudo-ventrally
52
What is the function of vulva?
1. copulation 2. urinary passage 3. parturition
53
What is clitoris?
1. Female homologue of penis 2. lies in ventral commissure 3. consists of: body/ crura/ glans (in clitoral fossa)
54
Lymphatic drainage of female genital tract. (i) Cranial repro tract: (ii) caudal repro tract:
(i) aortic lymph node + medial iliac lymph node (ii) medial iliac lymph node + pelvic lymph nodes
55
state the 4 classifications of placentas.
1. Foetal membrane development 2. Distribution of the placenta 3. histological structure of maternal-foetal interface 4. loss of maternal tissue
56
What is blastocoele?
empty space in blastocyst
57
state the 3 stages of implantation.
1. Apposition: The blastocyst contacts the implantation site of the endometrium 2. Adhesion: Trophoblast of the blastocyst attach to the receptive endometrial epithelium 3. Invasion: Invasive trophoblast cells cross the endometrial epithelial basement membrane and invade the endometrial stroma .
58
what is trophoblast?
the outmost layer (like epithelium)
59
what are the 3 layers of cells within the trilaminar embryonic disc? And what structures and tissues will they give rise to?
1. ectoderm (outermost): epidermis of skin/ nervous system 2. mesoderm (middle layer more than 1 layer): Somatic (bon, muscle and connective tissue)/ Splanchnic (serous membranes, smooth muscles, mesenteries) 3. endoderm: epithelial lining of GIT, respiratory tract, bladder and urethra
60
Gastrulation. What is the 2 layers that lateral mesodermal cells split into?
1. somatic mesoderm + ectoderm = somatopleure 2. splanchnic mesoderm + endoderm = splanchnopleure
61
what is the 4 extraembryonic membranes?
splanchnopleure: 1. yolk sac 2. allantois somatopleure: 3. amnion 4. chorion
62
Describe allantois.
- responsible for the vascularization of the chorion and amnion - blood vessels develop in the splanchnic mesoderm layer of allantoic membrane
63
What covers the surface of umbilical cord?
- the amnion covers the surface to the umbilical cord - Horse: allantois forms the distal surface of the cord
64
In what species can you find amniotic plaques?
horse and cows (ruminant)
65
Describe allantoic fluid.
- contains hippomanes (common in horse, might be present in ruminants and pigs)
66
What does it call when animal has excessive amniotic fluid?
hydramnion
67
what is the process of implantation?
apposition > adherence > attachment - junction complexes prevent the dislodgement of the blastocyst to prevent tissue damage
68
3 implantation classification.
1. centric 2. eccentric 3. interstitial
69
What is the 4 distribution of placental zone.
1. Diffuse (horse, pig) 2. cotyledonary (ewe, cow) 3. zonary (dog, cat) 4. discoidal (man, rodent)
70
What is the 3 classification for embryonic membrane
1. epitheliochorial placenta (pig, horse, ruminant) 2. endotheliochorial placenta (dog, cat) 3. haemochorial placenta (human, rodent)
71
placental classification: loss of maternal tissue at parturition.
1. deciduate 2. non-deciduate 3. partially deciduate
72
Which species have areolae?
sow - chorionic
73
Which specie (s) have microvilli on chorionic surface?
pig cow
74
which specie(s) have microcotyledons?
mare (foetal connective tissue)
75
Which specie(s) have crypts?
Mare (maternal tissue)
76
what are endometrial cups?
endometrial cups are depressions on endometrial surface, overlying hormone producing cells.
77
Which specie(s) have cotyledon?
cow
78
What is placentome?
Caruncles + cotyledon = placentome
79
What is peripartum period mean?
= time before, during, and after giving birth. Including changes of: 1. foetus body system towards independent survival 2. foetus positioning towards exit from the body 3. reproduction system of pregnant animal 4. parturition 5. expulsion of foetal membranes 6. involution of the reproduction tract after parturition
80
Terminology describing the presentation of foetus.
1. longitudinal (anterior/ posterior) 2. transverse (dorsotransverse/ ventrotransverse) 3. vertical
81
Terminology describing the position of foetus.
1. dorsal 2. ventral 3. left 4. right
82
Terminology describing the posture of foetus.
1. flexion 2.extension
83
state the 4 obstetrical operations
1. Re(tro)pulsion (push back) 2. Rotation (rotating long axis) 3. Version (rotation transverse axis) posterior or anterior 4. Extension and adjustment of extremities
84
State the parturition stages.
1. preparation of tract and foetus for delivery 2. delivery of foetus 3. expulsion of foetal membranes (placenta expulsion); involution of reproductive tract after parturition
85
What is the 4 main changes of puerperium?
1. uterine involution 2. Histological changes reversed 3. Resumption of ovarian function 4. self defence
86
What is lochia?
- vaginal discharge after giving birth - mix of blood, mucus and uterine tissue - shouldn't smell badly
87
what is dystocia?
1. Foetal maldisposition 2. heredity 3. management 4. injur
88
what is post partum?
- it's the period after parturition including lactation, weaning.