Female anatomy and histology Flashcards
What is the function of ovary?
- development and maturation female gemr cells
- production of reproductive hormones
Describe the structure of the ovary.
- mesovarium
- part of the supportive apparatus - germinal epithelium
- simple cuboidal epithelium
- continuous with serosal epithelium of the peritoneum - tunica albuginea
- cortex
- connective tissue enclosing follicles and corpus luteum/corpora lutea - medulla
- loose connective tissue containing blood and lymph vessels, nerves
Where can the ovarian follicles (primary oocyte & follicular cells) be found?
cortex
State the stages of the development of follicles in the cortex.
- Primordial follicle
- Primary follicle
- Secondary follicle
- Tertiary follicle
- Mature follicle
- Corpora lutea
Describe primordial follicles
- primary oocyte and single layer of flattened follicular cells
- “resting” follicles
- form prenatally
Describe primary follicles.
- primary oocyte surrounded by simple cuboidal follicular cells
- slight increase in size
Describe Secondary follicles.
- primary oocyte surrounded by at lease 2 layers of cuboidal to columnar follicular cells
- changes from follicular cells to granulosa
- substantial increase in size
- differentiation of stromal cells into theca follicularis
development of zona pellucida (protein layer)
Describe tertiary follicles.
- presence of large, fluid filled cavity (antrum)
- follicular cells differentiate into basal cells/ intermediate cells and granulosa cells
- development of cumulus oophorus
- stratification of theca follicularis
How does corpus luteum form?
At ovulation > follicle ruptures > corpus hemorrhagicum
- blood clots form in antruym due to rupture of vessels
What is the structure of tubular organ?
- Tunica mucosa
- epithelium
- lamina propria - Tela submucosa
- Tunica muscularis
- Tunica serosa/ adventitia
Describe the layers of uterine tube.
- Tunica mucosa/ sub-mucosa
- Epithelium: simple to pseudostratified columnar epithelium
- Ciliated and non ciliated cells (peg-cells)
- non-ciliated: mucus secreting cells
- microvilli on both ciliated and non-ciliated cells - Tunica muscularis
- inner circular/ outer longitudinal
- thinner cranially and thicker caudally (isthmus) - Tunica serosa
- Lies within mesoalpinx (extension part of broad ligament)
- Lies in the abdominal cavity
- Broad ligament also attaches to these structures
What is 3 structures of uterus ?
body (corpus), body (cornua) and cervix
State the 3 layers that the uterus consist of.
- Endometrium (tunica mucosa/ submucosa)
- strata functionalis
- strata basalis - Myometrium (tunica muscularis)
- inner circular
- vascular layer
- outer longitudinal layer - Perimetrium (tunica serosa)
Describe endometrium of uterus.
- Stratum functionalis (functional zone/ layer)
- degenerates after pregnancy/ oestrus
- surface epithelium (simple columnar to pseudostratified )
- subepithelial part: loose connective tissue, simple coiled tubular uterine glands, growth stimulated by oestrogen - Stratum basalis (basal zone/ layer)
- persists throughout
- functional zone restored from this layer (faces luminal side)
- uterine glands: stimulated by oestrogen > increase the thickness of layer as gland is active
Describe the myometrium of the uterus.
- smooth muscle fibre bundles
- thick inner layer (circular)
- outer longitudinal layer
- vascular layer in between
- fibres of the out layer extend into broad ligament
Describe the layer of cervix.
- Tunica mucosa/ submucosa
- highly folded
- no uterine glands
- simple columnar epithelium with goblet cells (gland cells/ only embedded on the surface of epithelium/ mucus produced changes depending on the cycle)
- extensive venous supply - Tunica muscularis
- very thick inner circular layer (with elastic fibres for pregnancy)
- less developed outer, longitudinal layer - Tunica serosa
Describe the layer in Vagina/ Vestibule
- Tunica mucosa/ submucosa
- stratified squamous epithelium > undergoes cyclic changes
- lymphoid nodules
- fold reduce lumen
- vestibule glands (branched, tubular, mucous glands) - Tunica muscularis
- 2 layers
- Inner circular and outer longitudinal - Tunica serosa
- only present in cranial part
- mostly retroperitoneal > adventitia
What is mammary gland composed of?
- glandular tissue
- connective tissue septa
Mammary complex structures
Alveolus > lobules > lobe
What is the milk pathway in mammary complex structure?
Small excretory passages (intralobular ducts) > interlobular ducts > Lactiferous ducts (large milk ducts) > Lactiferous sinus > teat canal
Describe alveolus histologically.
- secretory part
- simple cuboidal epithelium
- columnar when active - myoepithelial cells
- with contractile properties
- sits between the actual cell and the basal membrane
- contraction of myoepithelial cells > milk flow
What is the 3 structures that consist in the teat?
- teat wall
- smooth muscle cells (longitudinal and circular; form a sphincter around teat canal
- network of collagen and elastic fibres - teat sinus
- bi-layered cuboidal - papillary duct
- short narrow canal
- with transition: change to keratinized stratified epithelium
- longitudinal folds
- circular smooth muscle > sphincter
State the steps of parental mamogenesis.
Mammary ridge > primary mammary bud > Secondary mammary bud > canalization
Describe mammary ridge.
mammary ridges are thickened epidermal tissue (mammary crest) that give rise to the mammary gland.