Neurology Flashcards

1
Q

State some differentials for seizures in children

A
Syncope
Breath holding spells
Reflex anoxic seizures 
Daydreaming 
Tics
Self-gratification 
Psychologically induced events
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2
Q

Compare breath holding spells and reflex anoxic seizures

A

Breath holding: emotional event leads to crying then holding breath on exhalation. They go limp, collapse and may have brief clonic jerks

Reflex anoxic seizures: fear or pain leads the child to stop breathing. They go pale and limp and can seize

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3
Q

A child presents to A&E seizing, what needs to be ruled out?

A
Hypoglycaemia 
Hypoxia 
Fever
Meningitis 
Intracranial bleed
Hypercalcaemia 
Toxins
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4
Q

Compare simple and complex febrile seizures

A

Simple:

  • <15 minutes
  • only one event per fever
  • complete recovery within an hour

Complex:

  • > 15 minutes
  • may have focal features
  • can reoccur within same fever
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5
Q

How should parents manage febrile seizures?

A
  • cool blankets and fluids during a febrile illness
  • if seizing then clear the area
  • can give rectal diazepam
  • call 999
  • check for non-blanching rash
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6
Q

Describe myoclonic, tonic and clonic

A

Myoclonic: electric like shock movements
Tonic: sustained contraction
Clonic: rhythmic jerking

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7
Q

What does an EEG of absence seizures show?

A

3 - 4 Hz spike and wave

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8
Q

How would an occipital focal seizure present?

A

bright coloured flashing lights

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9
Q

How would a centroparietal focal seizure present?

A
  • spreading sensorimotor phenomenon

- paraesthesia

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10
Q

How would a temporal focal seizure present?

A
  • lip smacking
  • plucking at clothes
  • de ja vu
  • post ictal dysphasia
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11
Q

How would a frontal focal seizure present?

A
  • dystonic posture
  • guttural noises
  • Jacksonian march
  • post ictal weakness
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12
Q

Wests syndrome/ infantile spaspsm:

a) age of onset
b) description of child
c) EEG
d) management

A

a) <1 year
b) flexion of limbs and trunk followed by arching of back and extended arms - lasts seconds but can get 50+ in a row. Developmental delay
c) hypsarrhythmia
d) Vigabatrin

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13
Q

Dravet syndrome/ severe myoclonic:

a) age of onset
b) description of child

A

a) <1 year

b) focal or general, affecting one side of body. Development delay after a couple of years

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14
Q

Lennox-Gastoux:

a) age of onset
b) description of child
c) EEG
d) management

A

a) < 4 years
b) complete variety of seizure types
c) slow spikes
d) ketogenic diet

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15
Q

Janz syndrome/ juvenile myoclonic:

a) age of onset
b) description of child
c) EEG
d) management

A

a) teenagers
b) myoclonic seizure on waking up +/- GTC and absence.
c) generalised spike and wave
d) valproate

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16
Q

What are the types of focal and diffuse primary head injury?

A

Focal: haematoma and contusion
Diffuse: DAI and concussion

17
Q

Describe the CT appearance of an intraventricular haemorrhage

A

Hyperdense in the ventricles

18
Q

State some indications for an immediate CT head in a child

A
  • LOC > 5mins
  • GCS < 14
  • Focal neurological deficit
  • seizures
  • Signs of basal skull fracture
  • amnesia
  • 3 episodes of vomiting
  • tense fontanelle
19
Q

Aside from a typical migraine, how else might migraines present in children?

A

Hemiplegic
Basilar (aura + syncope with minimal headache)
Cyclical vomiting
Abdominal migraine

20
Q

What is the stepwise management of migraines in children?

A
  1. NSAIDs and intranasal sumatriptan for acute attacks
  2. Propranolol for prophylaxis
  3. prochlorperazine
21
Q

Define cerebral palsy and state some causes

A

Non-progressive, permanent disorder of movement and posture arising during development

  • Hypoxia
  • Teratogenic drugs
  • Infections
22
Q

What are some neonatal/ infantile signs that a child may have cerebral palsy?

A
  • low apgar score
  • floppy
  • hand preference < 18 months
  • delay in gross motor development
  • toe walking
  • persistent primitive reflexes
23
Q

What are the 3 types of cerebral palsy and what part of the brain is affected in each?

A

spastic: corticospinal tracts
ataxic: cerebellum
dyskinetic: basal ganglia

24
Q

Describe the features of spastic cerebral palsy

A
  • upper limb in fixed flexion
  • lower limb extended knee and plantar flexed foot leading to hemiplegic gait
  • equinovarus foot
  • increased tone with jerky movements
  • slow, slurred speech
25
Q

Describe the features of ataxic cerebral palsy

A
  • wide based gait
  • intention tremor
  • movements with abnormal force and inaccuracy
26
Q

Describe the features of dyskinetic cerebral palsy

A
  • involuntary movements triggered by attempts at control ones
  • can get chorea, dystonia and athesosis
27
Q

State some conditions associated with cerebral palsy

A
  • learning difficulties
  • hearing and sight difficulties
  • epilepsy
  • constipation and urinary incontinence
  • ADHD
28
Q

How can spasticity in cerebral palsy be managed?

A

Baclofen

Botulinum injections