Neurology Flashcards

1
Q

A child presents complaining of headaches, what would you want to ask?

A
  • Recurrence?
  • More than 1 type?
  • Warning?
  • SOCRATES
  • Use of analgesia?
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2
Q

What would you examine on a kid with a headache?

A

Growth parameters (height, weight, OFC, BP)
Sinuses & teeth
Visual acuity, fields and fundoscopy
Listen for cranial bruit
Focal neurological signs
Cognitive/emotional status

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3
Q

Headaches in kids fall into 4 groups:

A
  • Migraines
  • TTHs
  • Raised ICP
  • Analgesic Overuse
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4
Q

How would you make the diagnosis of a migraine?

A

Hemicranial, throbbing & pulsatile headache

Relieved by rest
Often photo/phonophobic

Presence of an aura

Also useful to look for FH

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5
Q

How would you diagnose a tension type headache?

A

If a child sufferes from a constant diffuse, symmetrical (band-like distribution) headache

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6
Q

How would you treat a migraine?

A

Give them simple analgesics for acute attacks
Maybe Triptans if bad enough

If atleast 1/wk give preventative drugs:
- Propranolol
- Amitriptyline
- Valproate

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7
Q

How do you manage a tension type headache?

A

Reassure the parent it’s nothing sinister

Attend to chronic underlying physical/psychological/emotional stressors

Discourage chronic use of analgesics

If necessary you can use simple analgesics acutely and amitriptyline preventatively

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8
Q

How would you spot a medication overuse headache

A

High use of PCM/NSAIDs (more problematic if with compound analgesics e.g. cocodamol)

Pain returns before they can have another dose

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9
Q

What would be red flags of a raised ICP headache?

A
  • Wakens them from sleep
  • Aggravated by raising ICP e.g. coughing, toilet straining or bending over
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10
Q

Headaches are diagnosed clinically, when would you want to use imaging?

A

1) Cerebellar dysfunction e.g. ataxia
2) Raised ICP
3) New focal deficit e.g. new squint
4) Seizures
5) Personality change
6) Unexplained deterioration in schoolwork

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11
Q

What are the major causes of fits/falls/funny turns in kids?

A

1) Epilepsy
2) Acute Symptomatic seizures e.g. febrile convulsion
3) Reflex Anoxic Seizures
4) Syncope
5) Parasomnias e.g. night terrors
6) Psychogenic Seizures

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12
Q

What causes reflex anoxic seizures?

A

Trigger e.g. pain or fright –> Vagal overactivity –> bradycardia –> hypoxia & seizure

It’s not abnormal in toddlers

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13
Q

What is an Acute Symptomatic Seizure?

A

A response to an acute insult e.g. hypoglycaemia, infection or hypoxia

The most common form is a Febrile Convulsion (very common, ~1in20 kids). Seizure ass with fever but with no intracranial inf or defined cause

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14
Q

What can you use to diagnose epilepsy?

A

Mostly a clinical diagnosis!!!
- History
- Video recordings
- ECG
- Interictal/Ictal EEG
- MRI (For malformations)
- Genetics (Familial & single gene disorders e.g. Tuberous Sclerosis)
- Metabolic tests if ass with developmental delay

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15
Q

What causes epilepsy in kids?

A

Mostly it’s idiopathic

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16
Q

Is childhood epilepsy generalised or focal?

A

Mostly generalised

17
Q

What factors are important when determining drug treatment for epilepsy?

A
  • Age
  • Gender
  • SEizure type
  • Epilepsy type
18
Q

What drugs do we use for childhood epilepsy?

A

Generalised = Sodium Valproate
Focal = Carbamazepine

New better tolerated drugs e.g. Lamotrigine

19
Q

What are the major SEs of Anti-Epileptic Drugs (AEDs)?

A

CNS - Drowsiness, impacted learning, cognition & behaviour

Others include rashes & bone marrow problems

20
Q

Other than AEDs how can you treat epilepsy?

A

Some forms respond to Vagus Nerve Stimulation or Surgery

21
Q

What signs would raise concern of a neuromuscular disorder in a pre-walking child?

A
  • Floppy
  • Slips from hands
  • Paucity of limb movements
  • Alert but low motor activity
  • Delayed motor milestones
  • Myopathic facies
22
Q

What signs would suggest a neuromuscular disorder in a walking child?

A
  • Frequent falls
  • Awkward/clumsy positioning e.g. holding shoulders back, belly out, walking on toes
  • Gait e.g. waddling
  • Pes Cavus & hammer toes
23
Q

What is pes cavus and hammer toes indicative of?

A

Charcot Marie Tooth Disease

24
Q

How can you differentiate a neuropathy from a myopathy?

A

Myopathy:
- Proximal weakness
- Purely motor
- Preserved reflexes
- Contractures
- ~Myocardial dysfunction

Neuropathies:
- Distal weakness
- ~sensory involvement
- Loss of reflexes
- ~Fasciculations

25
List some of the major neuromuscular disorders in kids?
Muscular dystrophies e.g. Duchenne's Spinal Atrophy Myasthenia Gravis
26
How is Duchenne's MD inherited?
X-linked --> female carriers and male suffers Xp21 - the dystrophin gene
27
How would you expect Duchenne's MD to present?
Delayed gross motor skills Symmetrical proximal weakness Waddling gait Calf hypertrophy Gower's Sign ~ Cardiomyopathy & Resp involvement in teens
28
How do you confirm Duchenne's?
Gower's sign (required but not specific) Raised CK (>1000)
29
How do we treat Duchenne's?
Steroids, thanks to this sufferers can stay on their feet etc much longer and live into early 30s
30
What's the most common cause of collapse in kids/adolescents?
Vasovagal Syncope
31
What questions would you ask about a collapse/fit/fall to ascertain cause?
- Any precipitant? - Any prodromal symptoms? - Timescale - Time to recover - Fh of epilepsy, syncope etc - H/o collapse - Fever/illness 3rd party: - Eye movement - Limb movement - Colour - Response/consciousness
32
What can cause vasovagal syncope?
- Missing meals (hypoglycaemia) - Dehydration - Stress - Posture change - Heat - Straining - Blood taking - Arrythmia e.g. Long QT
33
What can you test in syncope?
Glc at the time ECG for arrhythmia BP for hypotension
34
What advice would you give someone who suffers from syncope?
- Reassure that it's not something serious - Drink lots - Have proper meals - Take care on changing posture - Return if it recurs - Exercise legs (improves venous return)