Neurology Flashcards

1
Q

What can cause headaches in children?

A
  • simple tension headaches
  • migraines
  • ear, nose and throat infections (sinusitis)
  • analgesic (overuse) headache
  • problems with vision
  • raised intracranial pressure
  • brain tumours
  • meningitis or encephalitis
  • carbon monoxide poisoning
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2
Q

Describe a tension headache?

A
  • mild ache across forehead - typically symmetrical
  • band like pressure around the head
  • come on and resolve gradually
  • don’t cause visual changes or pulsating sensation
  • young children may become quiet, pale and tired
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3
Q

What can trigger tension headaches in children?

A
  • stress, fear or discomfort
  • skipping meals
  • dehydration
  • infection
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4
Q

How should tension headaches be managed?

A
  • reassurance, analgesia, regular meals, avoid dehydration and reduce stress.
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5
Q

How does a migraine present?

A
  • unilateral, severe headache
  • throbbing in nature
  • takes longer to resolve than tension

Associated with
- visual aura
- photophobia and phonophobia
- nausea and vomiting
- abdo pain

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6
Q

How are migraines in children managed?

A
  • rest, fluids and low stimuli environment
  • analgesia - paracetamol, iBuprofen
  • sumatriptan
  • antiemetics (domperidone)
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7
Q

What can be given for prophylaxis of migraines?

A
  • propranolol (avoid in asthma)
  • Pizotifen (often causes drowsiness)
  • topiramate (teratogeneic so give contraceptive in girls of child bearing age)
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8
Q

What are breath holding spells?

A

Involuntary episodes where a child holds their breath - usually triggered by something upsetting or scaring them.

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9
Q

What age group are affected by breath holding spells?

A

6 and 18 months of age. Most children outgrow them by 4 or 5 years.

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10
Q

What are the two types of breath holding spells?

A
  • cyanotic
  • pallid - also known as reflex anoxic seizures
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11
Q

What happens during a cyanotic breath holding spell?

A
  • when the child is really upset, worked up and crying
  • let out a long cry and then stop breathing, become cyanotic and lose consciousness
  • gain consciousness again within a minute
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12
Q

What happens during a reflex anoxic seizure / pallid breath holding spell?

A
  • when child is startled
  • vagus nerve sends strong signals to the heart, causing it to stop
  • child will suddenly go pale, lose consciousness and may have some seizure-like muscle twitching
  • within 30 seconds the heart restarts and they become conscious again
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13
Q

How should breath holding spells be managed?

A
  • exclude other pathology
  • reassure parents
  • do FBC as linked with iron deficiency anaemia. Treat if needed.
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14
Q

What is a squint?

A

Misalignment of the eyes

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15
Q

What is another name for a squint?

A

Strabismus

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16
Q

What is amblyopia?

A

When the misaligned eye becomes ‘lazy’ because the other one becomes dominant. The ‘lazy eye’ becomes more disconnected from the brain, making the problem worse.

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17
Q

What is esotropia?

A

Inward positioned squint eye (towards nose)

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18
Q

What is exotropia?

A

Outward positioned squint (towards ear)

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19
Q

What is hypertropia?

A

squint where affected eye moves upwards

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20
Q

What is hypotropia?

A

squint where affected eye moves downwards

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21
Q

What can cause squints?

A
  • usually idiopathic
  • hydrocephalus
  • cerebral palsy
  • space occupying lesions (e.g. retinoblastoma)
  • trauma
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22
Q

Do i need to know the special tests for eye squints??

A
  • fundoscopy
  • visual acuity
  • Hirschberg’s test
  • Cover test
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23
Q

How are squints managed?

A
  • start treatment before 8 ( this is when the visual fields stop developing)
  • occlusive patch- cover good eye - forcing the weaker eye to develop
  • see specialist ophthalmologist
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24
Q

What are febrile convulsions?

A

A type of seizure in children with a high fever (between 6 months and 5 years)

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25
Q

What are simple febrile convulsions?

A

Generalised, tonic clonic seizures, lasting less than 15 mins. Only occur once during a single febrile illness

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26
Q

What are complex febrile convulsions?

A

Consist of partial or focal seizures, last more than 15 mines or occur multiple times within the same febrile illness

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27
Q

What are differentials for a febrile convulsion?

A
  • epilepsy
  • meningitis, encephalitis or other neuro infections
  • intracranial space occupying lesions
  • syncope
  • electrolyte abnormalities
  • trauma
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28
Q

How are febrile seizures managed?

A
  • find underlying cause and treat
  • treat fever with ibuprofen or paracetamol
  • simple febrile convulsions do not need investigating
  • give parents advice around how to deal with if another occurs
29
Q

What is cerebral palsy?

A

Permanent neurological problems occurring due to damage to the brain around the time of birth. This means there is a huge variation in severity and type of symptoms.

30
Q

What can cause cerebral palsy?

A

Antenatal
- maternal infections
- trauma during pregnancy
Perinatal
- birth asphyxia (deprived of oxygen)
- pre-term birth
Postnatal
- meningitis
- severe neonatal jaundice
- head injury

31
Q

What are the different types of cerebral palsy?

A
  • spastic - hypertension and reduced function due to damage to upper motor neurones
  • dyskinetic - problems controlling muscle tone - hyper and hypotonia - causing athetoid movements and oro-motor problems - due to damage to the basal ganglia
  • ataxic - problems with co-ordinated movement - due to damage to the cerebellum
  • mixed
32
Q

What is a different name for spastic cerebral palsy?

A

Pyramidal CP

33
Q

What are the different names for dyskinetic cerebral palsy?

A

Athetoid or extrapyramidal CP

34
Q

What are the patterns of spastic cerebral palsy?

A
  • monoplegic - one limb affected
  • hemiplegic - one side of the body
  • diplegic - 4 limbs affected but mostly the legs
  • quadriplegic - 4 limbs affected more severely
35
Q

What are the signs or symptoms of cerebral palsy?

A
  • failure to meet milestones
  • increased or decreased tone
  • hand preference below 18 months
  • problems with co-ordinations, speech or walking
  • feeding or swallowing problems
  • learning difficulties
36
Q

Go over upper vs lower motor neurone injuries properly!!

A
37
Q

What are the features of upper motor neurone lesions?

A
  • muscle bulk preserved
  • hypertonia
  • power slightly reduced
  • brisk reflexes (hyper-reflexia)
38
Q

What are the features of lower motor neurone lesions?

A
  • reduced muscle bulk with fasciculations
  • hypotonia
  • dramatically reduced power
  • hyporeflexia
39
Q

What does a hemiplegic / diplegic gait indicate?

A

upper motor neurone lesion

40
Q

What does a broad based/ ataxic gait indicate?

A

a cerebellar lesion

41
Q

What does a high stepping gait indicate?

A

foot drop or a lower motor neurone lesion

42
Q

What does a waddling gait indicate?

A

pelvic muscle weakness due to myopathy

43
Q

What does a antalgic gait indicate?

A

localised pain

44
Q

What conditions are associated with cerebral palsy?

A
  • learning disability
  • epilepsy
  • kyphoscoliosis
  • muscle contractures
  • hearing and visual impairement
  • GORD
45
Q

How is cerebral palsy managed?

A
  • manage symptoms and maximise function
  • physiotherapy
  • occupational therapy
  • speech and language therapy
  • dieticians
  • ortho surgeons - e.g. to release contractures
  • medications such as muscle relaxants, anti-epileptics etc.
  • social workers and support groups
46
Q

What is syncope?

A

Temporary loss of consciousness due to a disruption of blood supply to the brain, often causing a fall. Also known as vasovagal or fainting.

47
Q

What happens during a vasovagal episode?

A
  • vagus nerve receives a strong stimuli - e,g, emotional event, pain, change in temp
  • stimulates parasympathetic nervous system
  • causes vasodilation, hence dropping the blood pressure in the cerebral circulation
  • leading to hypo perfusion and then a loss of consciousness
48
Q

What are the signs and syndromes of the prodrome before syncope?

A
  • hot or clammy
  • sweaty
  • heavy
  • dizzy or lightheaded
  • vision going blurry or dark
  • headache
49
Q

What can cause syncope?

A

Primary
- dehydration, missed meals, extended standing, vasovagal response to a stimuli
Secondary
- hypoglycaemia
- dehydration
- anaemia
- infection
- arrhythmias
- heart disease

50
Q

What examination and investigation should be done after syncope?

A
  • any physical injuries?
  • any concurrent illness?
  • neuro examination
  • lying and standing blood pressure
  • cardiac examination and ECG (potentially echocardiogram)
  • bloods - FBC, electrolytes and blood glucose
51
Q

How should syncope be managed?

A
  • exclude other pathologies
  • reassure and give simple advice
  • avoid dehydration, don’t skip meals, avoid prolonged standing
  • when experiencing prodromal symptoms, sit or lie down, have some water and something to eat and rest
52
Q

What is craniosynostosis?

A

Premature closure of the skull sutures - causing abnormal head shapes and restriction to the growth of the brain, hence raised ICP.

53
Q

What symptoms can craniosynostosis cause?

A
  • abnormal head shape that is small in proportion to the body
    Symptoms of raised ICP
  • developmental delay
  • cognitive impairment
  • vomiting
  • irritability
  • visual impairment
  • neurological symptoms
  • seizures
54
Q

How is craniosynostosis managed?

A
  • if mild = monitor and follow up over time
  • more severe = surgical reconstruction of the skull
    This has good prognosis with proper management
55
Q

What is plagiocephaly and brachycephaly?

A

Abnormal head shapes in otherwise normal healthy babies. This is very common

56
Q

What is hydrocephaly?

A

Abnormal build up of CSF within the ventricles in the brain and spinal cord.

57
Q

What are the common causes of hydrocepahlus?

A

Can be due to problems with over production, drainage or absorption.
- Aqueductal stenosis = most common - cerebral aqueduct between the 3rd and 4th ventricles is narrowed.
- arachnoid cysts
- other congenital malformations or chromosomal abnormalities

58
Q

How does hydrocephalus present?

A
  • rapidly enlarging head circumference in babies (as the sutures haven’t yet fused)
  • bulging anterior fontanelle
  • poor feeding and vomiting
  • poor tone
  • sleepiness
59
Q

How is hydrocephalus commonly managed?

A

By surgically creating a ventriculoperitoneal shunt - so that the CSF from the ventricles drains into the peritoneal cavity

60
Q

What are the complications to a ventriculoperitoneal shunt?

A
  • infection
  • can become blocked
  • excessive drainage of CSF
  • intraventricular haemorrhage during the surgery
  • child outgrows them - so need replacing about every 2 years
61
Q

What is Duchennes muscular dystrophy?

A

A X linked recessive genetic condition that causes gradual weakning and wasting of muscles. This is a defective gene for dystrophin on the X chromosome - this normally helps to hold muscles together at a cellular level

62
Q

How does Duchennes muscular dystrophy present?

A
  • Normally boys around 3-5 years.
  • weakness around their pelvis which is progessive until all muscles affected
  • Gowers sign (using a downward dog and then their legs to get up)
63
Q

What is the prognosis for Duchennes muscular dystrophy?

A
  • usually wheelchair bound by teenage years
  • life expectancy of 25-35 years - due to resp and cardiac complications
64
Q

How is Duchennes muscular dystrophy managed?

A

Supportive to ensure best quality of life
- occupational therapy
- physio - access to wheelchairs etc.
- management of any complications
Oral steroids - can slow progession slightly
Creatine supplements to slightly improve muscle strength

65
Q

What is spinal muscular atropy?

A

Rare autosomal recessive condition that causes progressive loss of lower motor neurones in the spinal cord and hence progressive muscular weakness

66
Q

What are signs of a lower motor neurone lesion?

A
  • fasciculation’s
  • hypotonia
  • hyporeflexia
  • reduced power
  • reduced muscle bulk
67
Q

How is spinal muscular atropy managed?

A
  • physiotherapy - maximising strength in muscles and retaining resp function. Access to walking aids / wheelchairs.
  • respiratory support may be needed
  • PEG feeding if unsafe swallow
68
Q

How is spinal muscular atropy managed?

A
  • physiotherapy - maximising strength in muscles and retaining resp function. Access to walking aids / wheelchairs.
  • respiratory support may be needed
  • PEG feeding if unsafe swallow