Neurological Viruses Flashcards
EEE & VEE Genome
+ssRNA
EEE & VEE Virion
enveloped
EEE & VEE Incubation
4-10 days
EEE & VEE Reservoirs
Reservoirs are Birds and small mammals
Common vectors are mosquitos and ticks
EEE & VEE Replication
In the Cytoplasm
Virus brought into the cell be cell-mediated endocytosis
EEE & VEE Symptoms
Chills, fever, malaise, arthralgia, myalgia
These last for 1-2 weeks
EEE & VEE Transmission
Introduced through the bite of an infected arthropod
Cells are infected locally and carried by Langerhan cells to LN
Replication and release into the blood stream where the infection spreads to CNS
EEE & VEE Complications
Can lead to Encephalitic disease in 5% of cases
- fever, headache, irritability, restlessness, vomiting, diarrhea, convulsions, and coma
- 1/3 of encephalatic cases die 2-10 days after onset
- Those who survive can have long term consequences such as seizures, personality disorders, and paralysis
EEE & VEE Prevalence
Seen mostly in eastern states
EEE & VEE Prevention
A single vaccine is available -TC-83
- contains live attenuated TC-83 and inactivated C-84
- only given to at risk military personel and researchers
EEE & VEE Treatment
No treatment, just supportive care to make the patient comfortable
West Nile Virus Genome
(+)ssRNA
West Nile Virus Virion
Enveloped
West Nile Virus Incubation
2-14 days
West Nile Virus Replication
Cytoplasm