Neurological Infections

Question 1

Normal values on LT

1. Opening pressure
2. WBCs
3. Protein
4. Glucose

Answer 1

1. 50 - 80 mmHg
2. 0 - 5
3. 20 - 45 mg/dL
4. 2/3 of serum glucose

Question 2

Most common cause of bacterial meningitis in:

1. Neonates
2. Children >1 yr and adults
3. Elderly
4. Chronic lung disease
5. Sinusitis, otitis media
6. Neurosurgical patients
7. Immunosuppressed / elderly

Answer 2

1. Group B strep
2. Strep pneumoniae, Nesseria meningitidis
3. S. pneumoniae and gram-(-) enteric bacilli
4. Pseudomonas
5. Nontypeable H. influenzae, S. pneumoniae
6. S. pneumoniae, nontypeable H. influenzae, S. aureus
7. Listeria monocytogenes

Question 3

Unlike other bacterial meningitidis, meningitis caused by this organism presents with lymphocytic pleocytosis and often normal CSF glucose.

Answer 3

Listeria monocytogenes

Question 4

Total duration of therapy in bacterial meningitis

Answer 4

10 - 14 days

Question 5

Empiric regimen in bac meningitis

Answer 5

Vanco 15mg/kg +

Cefotaxime 50mg/kg / Ceftriaxone 100mg/kg

Question 6

Test of choice for brain abscess

Answer 6

MRI with contrast

(+) Ring-enhancing lesion

Question 7

Empiric regimen for brain abscess. Duration of therapy?

Answer 7

Metronidazole + Third-Gen cephalosporin

4 - 8 weeks

Question 8

Most common neurological syndrome in HIV infection

Answer 8

Encephalopathy and AIDS dementia complex

Question 9

The presence of nonclearing (atraumatic) RBCs in CSF suggest infection with this organism.

Answer 9

HSV

Causes hemorrhagic encephalitis

Question 10

Diagnostic test of choice for HSV encephalitis

Answer 10

HSV PCR of CSF

Question 11

Schedule of rabies vaccine administration, post-exposure prophylaxis

Answer 11

As soon as possible, day 3, 7, 14 28

Human rabies immunoglobulin also given at the same time as the first dose; or within 7 days.

Question 12

Most common neurologic manifestation of Syphilis

Answer 12

Meningitis