NEUROLOGIC NURSING Flashcards
In ICP: Drug to decrease cerebral edema
Dexamethasone (Decadron)
Dexamethasone (Decadron) classification
CORTICOSTEROIDS
IN ICP: Promotes cerebral diuresis by decompressing brain tissue
Mannitol (Osmitrol)
Classification of mannitol
Osmotic Diuresis
main function of Henle’s loop
aims to reduce the volume of water and solutes within the urine without any change in its concentration.
Loop diuretic: ____
Furosemide
Furosemide acts in how many hours
6 hours
Infusions are monitored closely in ICP because
because of the risk of promoting additional cerebral edema and fluid overload
IN ICP: What position
Semifowlers
Monitor neuro status every ____
1-2 hrs
What to avoid in ICP
Avoid pressure like: Coughing, Straining of stools, valsalva manuever, excessive vomiting
In ICP: Seizure can also occur. Give what medication?
Phenytoin (dilantin)
ICP: What to give if have headache?
Codeine Sulfate
ICP: Limit fluids to _________
1200 liters/day
ICP: Maintain a patent airway because
because a high carbon dioxide (CO2) level increases intracranial pressure
Confirmatory test for Multiple Sclerosis
MRI
purpose of plasmapheresis
eliminates the antibodies in the plasma that are causing the autoimmune attack, and then returns the “cleaned” plasma and other blood components back to the body
MS:
What is more priority: Acute or Chronic exacerbation
ACUTE EXACERBATION
MS: MUSCLE RELAXANTS MEDS
Baclofen (Lioresal) & Dantrolene Na (Dantrene)
antiviral, antiparkinsonian, helps in fatigue
amantadine
MS: for tremors
propanolol
MS: key agent for acute relapse and shortens duration of relapse
IV methylprednisolone
MS: immunosuppressants drugs for chronic exacerbation
avonex, rebif
Atrophy of brain tissue to deficiency of SANS
Alzheimer’s Disease
what is SANS in alzheimers
Somatostatin, Acetylcholine, Norepinephrine, Substance P
initial sign of alzheimers disease
Progressive memory loss
5 A’s in alzheimers disease
amnesia, anomia, agnosia, apraxia, aphasia
In 5A’s, what is common in alzheimers
APHASIA
CONFIRMATORY TEST FOR ALZHEIMERS
AUTOPSY
DOC ALZHEIMERS
DONEPEZIL
PRIORITY FOR ALZEIMERS
SAFETY
PARKINSONS DISEASE: WEAKNESS OR NON
NO WEAKNESS
PARKINSONS DISEASE: WHAT NUEROTRANSMITTOR DECREASE
DOPAMINE
INITIAL SIGN IN PARKINSONS DISEASE
TREMORS
MNEMONIC TO REMEMBER IN PARKINSONS DISEASE
PARC DARK!
Pill rolling
About to fall: Shuffling Gait
Rigidity
Cant swallow, speak
Drugs
Artane
Resting Tremor
Keep tremors down with antihistamine
common surgery in PARKINSONS DISEASE
deep brain stimulation
drugs for PARKINSONS DISEASE
levodopa, carbidopa
combination of levodopa and carbidopa
sinemet
controls dyskinesias in long term use of Levodopa
Amantadine HCL (symmetrel)
What to consider in taking antiparkinsonian
-take before meals for increase absorption
-inform patient that urine stool may be darkened
Chronic autoimmune disorder in impulse transmission at neuromuscular junction
MYASTHENIA GRAVIS
WHAT IS AFFECTED IN MYASTHENIA GRAVIS
VOLUNTARY MUSCLES
MG: ANTIBODIES ATTACK WHAT RECEPTOR ____ LEADING TO ______
ACTH Leading to muscle relaxation –> muscle weakness
MG: INITIAL SIGN
PTOSIS
MG: CONFIRMATORY TEST
TENSILON TEST
MG: WHAT HAPPENS IN TENSILON TEST
IT STRENGTHENS MUSCLES FOR 5-10 MINS
TENSILON TEST: SHORT TERM OR LONG TERM
SHORT TERM
MG: SURGERY
THYMECTOMY
MG: MEDICATION WHICH INHIBITS CHOLINESTERASE
CHOLINERGIC/ANTI CHOLINESTERASE
MG: DRUGS IN CHOLINERGIC/ANTI CHOLINESTERASE
Pyridostigmine (Mestinon)
Neostigmine (Prostigmin)
MG: IMMUNOSUPPRESSANTS
Azathioprine and Methotrexate
MG: SUPPRESS IMMUNE RESPONSE
Corticosteroids
MG: Under medication
MYASTHENIC CRISIS
MG: MANIFESTATION IN MYASTHENIC CRISIS
Cant See
Cant Swallow
Cant breathe
Increase BP, HR, RR, Decrease Urine Output
MG: OVER MEDICATION
CHOLINERGIC CRISIS
MG: MANIFESTATION IN CHOLINERGIC CRISIS
PNS!!
S - SALIVATION
L - lacrimation
U - urination
D - defecation
G - GI distress
E - emesis
Hypotension, Pupillary Miosis
INITIAL SIGN IN GBS
CLUMSINESS
IN GBS. WHAT IS THE RESULT IN CSF ANALYSIS
increase protein but normal WBC
GBS: TO FIGHT GBS ANTIBODIES
IV IMMUNOGLOBLULINS
Disruption of cerebral blood flow due to obstruction by embolus or thrombus
ISCHEMIC STROKE
CAUSE OF ISCHEMIC STROKE
atherosclerosis, thrombus, embolism, DM, HPN, atrial fibrillation
initial diagnostic test for stroke
CT SCAN
ISCHEMIC VS. HEMORRHAGIC: DARK BLOOD SEEN IN CT SCAN
ISCHEMIC STROKE
ISCHEMIC VS. HEMORRHAGIC: BLOOD IS BRIGHT SEEN IN CT SCAN
HEMORRHAGIC STROKE
STROKE: DIAGNOSTIC TEST TO CHECK FOR ATRIAL FIBRILLATION
12 LEAD ECG
STROKE: TO SEE IF THERE’S FORMATION OF PLAQUE
CAROTID ULTRASOUND
STANDARD TESTS for Stroke
CT Scan, MRI, 12-Lead ECG
MOST COMMON CAUSE OF CVA
THROMBUS –> EMBOLISM –> CEREBRAL HEMORRHAGE
ISCHEMIC STROKE MEDICATION: Give the Classification
THROMBOLYTIC AND ANTICOAGULANT
MNEMONIC FOR THROMBOLYTIC
UST!
UROKINASE
STREPTOKINASE
TPA
SIDE EFFECT OF UROKINASE
HYPERTENSION
MNEMONIC FOR TPA
ART
ALTEPLASE
RETEPLASE
TENECTEPLASE
SIDE EFFECT OF STREPTOKINASE
PRURITUS
SIDE EFFECT OF TPA
CHEST PAIN
drug of choice to STEMI
TENECTEPLASE
TPA CRITERIA
CRAB
CT SCAN
NO RECENT SURGERY
AGE - ALLOWED 18y/o ABOVE
BP CONTROLLED (should be <185/110), BLOOD TEST NORMAL
IN TAKING TPA, WHAT TO CONSIDER IN BLOOD TEST
Glucose: 70-100
INR: less than 1 sec; but if taking warfarin: 2-3 secs
Platelet: 150,000 to 450,000
best parameter of thrombolytic
EPISTAXIS
Anticoagulant drugs
Heparin
Coumadin
Direct Oral Anticoagulants
What to monitor in taking heparin
PTT.
In taking Heparin, if PTT is prolonged, give antidote of ___
Protamine Sulfate
NORMAL PTT
30-40 secs
In taking Warfarin, if PT is prolonged, give antidote of ___
Vitamin K and aquamephyton
normal PT
11-12 secs
What are the Direct Oral Anticoagulants
Dabigatran (Pradaxa)
Apixaban (Eliquis)
what are the Platelet Aggregation Inhibitors
ACT
Aspirin
Clopidogrel
Ticlopidine
adverse effect of aspirin
tinnitus
adverse effect of ticlopidine
GI discomfort
if warfarin is contraindicated, give _____
aspirin
aspirin can be given together with _____
clopidrogel
Bleeding into the brain tissue, ventricles, and subarachnoid space
HEMORRHAGIC STROKE
2 Types of Hemorrhagic Stroke
Primary intracerebral hemorrhage
Secondary intracerebral hemorrhage
Type of hemorrhagic stroke wherein from spontaneous rupture of small vessels caused by uncontrolled HPN
Primary intracerebral hemorrhage
Type of hemorrhagic stroke wherein associated with AVMs, cerebral aneurysm, neoplasm, or certain medications (anticoagulants)
Secondary intracerebral hemorrhage
more definitive diagnostic for HEMORRHAGIC STROKE
MRI
medication in hemorrhagic stroke
antihypertensive, fresh frozen plasma, anticonvulsant
DOC FOR SEIZURE
PHENYTOIN (dilantin)
In skull fractures, during glucose test for CSF, yellowish halo/ring sign indicates
CSF leakage
jarring of the brain (naalog)
concussion
brain is bruise/damage (nauntog)
contusion
LAYERS OF MENINGES
DAP
DURA
ARACHNOID
PIA
WHERE DOES SUBARACHOID SPACE IS PLACE
BELOW THE ARACHNOID
WHAT CONTAINS IN SUBARACHNOID
CONTAINS IN CSF
Between Skull and Dura mater
Epidural hematoma
Between dura and arachnoid mater
Subdural hematoma
Epidural hematoma: Arterial circulation —-> _________
Rapid hematoma development
Subdural hematoma: Venous bleeding —-> _________
slow hematoma development
Location of spinal cord injury: Quadriplegia
Respiratory muscle paralysis
cervical
Location of spinal cord injury: Paraplegia (lower body is paralyzed)
Poor control of upper trunk
Thoracic
Location of spinal cord injury:
Paraplegia
Bowel and bladder paralysis
Lumbar
In above sacral 2: male allow ___________ but no _________
male allow erection but no ejaculation
in sacral 2 to 4: no _______ & _________
no erection & ejaculation
Bowel and bladder incontinence
complication in spinal cord injuries
Spinal Shock (Neurogenic Shock) & DVT
Medical Management for meningitis
antibiotic: penicillin G + ceftriaxone
dexamethasone
Most common causative agent in meningitis
Streptococcus pneumoniae & Neisseria meningitidis