neurodevelopment Flashcards

1
Q

chorea

A

involuntary muscle contraction

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2
Q

dystonia

A

sustained muscle contraction

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3
Q

bradykinesia

A

delayed muscle contraction

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4
Q

ethanol is a neurotoxin (T/F)

A

T- FASD

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5
Q

what causes loss of motor control in huntingtons

A

basal ganglia degeneration

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6
Q

common cause of spina bifida occulta

A

low folic acid

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7
Q

Which disorder is caused by an expanded CAG repeat gene mutation?

A

Huntington disease

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8
Q

what occurs during initiation phase of seizure

A

synchronous depolarization
neuron recruitment

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9
Q

what occurs during tonic phase of seizure

A

overexcitation
loss of consciousness
muscle contraction
impaired autonomic functions

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10
Q

what occurs during clonic phase of seizure

A

inhibition convulsions (try to reset, can’t, repeat)

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11
Q

spina bifida occulta

A

incomplete vertebral column
asymptomatic

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12
Q

meningocele

A

sac with CSF protrude
spinal cord intact

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13
Q

myelomeningocele

A

intact sac containing spinal cord protrudes

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14
Q

open spina bifida

A

no skin covers the cyst (containing spinal cord)↑ risk of infection

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15
Q

Arnold‐Chiari malformation

A

the cerebellum and brainstem slip down through the foramen magnum–>hydrocephalus

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16
Q

seizure

A

sudden abnormal electrical activity (x1)

17
Q

epilepsy

A

recurrent seizures (xpl)

18
Q

focal seizure

A

localized to 1 area
remain conscious

19
Q

global seizure

A

multiple brain region impaired
lost consciousness

20
Q

provoked

A

cause of seizure is known

21
Q

status epilepticus

A

long lasting global seizure (5min+) series of rapidly recurring seizures

22
Q

absence seizure

A

lapses in consciousness for 10 seconds

23
Q

atonic seizure

A

sudden loss of postural muscle tone (head nod-fall)

24
Q

Neurochemical changes associated with Huntington disease

A

Decreased GABA
Increased DOPA

25
Q

pathogenesis of Huntington disease

A

Basal ganglia –>loss of motor control
Cerebral cortex–> loss of cognition

26
Q

Anencephaly

A

missing skull
anterior part of neural tube problem (fatal)

27
Q

encephalocele

A

protrusion of brain through skull into sac