neurodegenerative

Question 1

Which disease primarily affects the extrapyramidal system?

Answer 1

Parkinson disease

Question 2

What is the most common type of multiple sclerosis?

Answer 2

Relapsing-remitting

Question 3

which inclusions are located within the neuron

Answer 3

tangle and lewy body

Question 4

which inclusions are located outside the neuron

Answer 4

plaque

Question 5

common causes of dementia (4)

Answer 5

Alzheimer (most common)
Parkinson
vascular
mixed

Question 6

what is the order of MS mechanisms

Answer 6

1- Epstein-Barr infection
2- T cell activation
3- Oligodendrocyte damage
4- Neuron damage

Question 7

Which disease is treatable with an acetylcholine receptor agonist?

Answer 7

Alzheimer disease

Question 8

Which neurodegenerative disease does not appear to affect cognition?

Answer 8

ALS

Question 9

Which neurotransmitter produces tremor in Parkinson disease?

Answer 9

Acetylcholine

Question 10

Similarities between neurodegenerative diseases

Answer 10

inclusions, apoptosis, dementia (apoptosis and dementia =connected)

Question 11

Alzheimer disease vs Parkinson (location)

Answer 11

AD: Cerebral cortex, hippocampus
PD: Basal ganglia, Substantia nigra

Question 12

Alzheimer disease vs Parkinson (neurotransmitter)

Answer 12

AD: ↓ Acetylcholine
PD: ↓ Dopamine

Question 13

Alzheimer disease vs Parkinson (progression)

Answer 13

AD: Memory–>Executive
PD: opp.

Question 14

dementia

Answer 14

↓ and progressive failure of cerebral function
due to neuron loss
umbrella term

Question 15

mechanism of ALS

Answer 15

destroys motor neurons (upper and lower) -voluntary movement (pyramidal)

sensory neurons, cognition-intact

Question 16

pathogenesis of MS (6)

Answer 16

1. Autoimmune response
2. Immune system activation
   (T cells attack myelin)
3. Inflammation
4. Demyelination
5. Axonal damage
6. Scarring (sclerosis)