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Week 52: Psychosis > Neurobiology of Substance Use Disorders > Flashcards

Neurobiology of Substance Use Disorders Flashcards

1
Q

What happens to D2 receptors in addiction?

A

Lower
Receptor volume and sensitivity go down
Can recover after prolonged abstinence

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2
Q

Functions of DA pathways

A 
Reward
Pleasure, euphoria
Motor function
Compulsion
Perseveration
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3
Q

Function of serotonin pathways

A

Moof
Memory processing
Sleep
Cognition

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4
Q

Impulsivity

A

Driven by an effort to obtain arousal and gratification

NE and Da

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5
Q

Compulsivity

A

Driven by an effort to reduce anxiety

Serotonin

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6
Q

What is the problematic product in alcohol metabolism

A

Acetaldehyde

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7
Q

Effects of acetaldehyde

A 
Flushing
Tachycardia
HTN
Nausea
Vomiting
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Week 52: Psychosis (8 decks)

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