Neurobiology of cognition Flashcards
What are some of the aspects of cognition
Problem solving
Memory
Attention
Concentration
Judgement
Emotion
Spatial awareness
Calculation
Language
What are the 3 main types of memory?
Sensory memory (<1 sec)
Short-term memory (<1 min)
Long-term memory (Life-time)
Wha are the 2 types of long-term memory?
Explicit memory - Conscious
Implicit memory - Unconscious
What is a type of explicit memory?
Declarative memory - Facts and events
What are some types of declarative memory?
Episodic memory - Events and experiences
Semantic memory - Facts and concepts
What is a type of implicit memory?
Procedural memory - Skills and tasks (Muscle memory)
What is an MTA score?
Medial temporal atrophy score - Radiological score of the level of atrophy of the medial temporal lobe
What are the 4 cholingeric projections of the brain?
- Striatal interneurones
- Nucleus basalis of Meynert (Affected in AD)
- Medial septal nucleus
- Brain stem nuclei
What are some of the functions of the cholinergic system
- Memory, learning, motivation, attention, arousal and REM sleep
- Control of vagus nerve
- GI motility and secretions
- Gland secretions
- Urine release
- Near vision
- Sexual function
What effect will anticholinergics have on Memory, learning, motivation, attention, arousal and REM sleep
Confusions
Drowsiness
Agitation
Delirium
What effect will cholinesterase inhibitors have on memory, learning, motivation, attention, arousal and REM sleep
Confusions
Nightmares
What effect will anticholinergics have on vagus nerve control?
Tachycardia
Hypertension
What effect will cholinesterase inhibitors have on vagus nerve control?
Bradycardia
What effect will anticholinergics have on GI motility?
Constipation
What effect will cholinesterase inhibitors have on GI motility and secretion?
Diarrhoea
Nausea
What is the Yerkes-Dodson curve?
