Neuro Final - from quizlet - 1-53 Flashcards
Lesion in Conus Medularis
S2-S5 spinal cord
hyper emptying reflex
Neurogenic Bladder
Bilateral lesions required Incontinence (leak) Urge incontinence Overflow incontinence Stress incontinence = not neurogenic = postpartum females Urinary frequency Urinary hesitancy
Lesion in Pontine Micturation Center
or SC lesion communication to PMC
Detrusor-Sphincter Dyssynergia
emptying,
but residual urine in bladder
uncoordinated deltrusor contraction & urethral (ext) sphincter relaxation
Tx: Detrusor- Sphincter Dyssynergia
Botox -
inject into external urethral sphincter
Lesion (rostral to) above PMC
Uninhibited neurogenic bladder =
UMN overactive bladder
sensation normal
urge incontinence
normal initiation of voiding
no urinary rentention
Lesion in spinal cord disconnects SNS, PSNS, somatic reflex from PMC
(below PMC)
Automatic Neurogenic Bladder =
UMN overactive bladder
sensation decreased
urge incontinence
difficulty with initiation of voiding
urinary retention
LMN / underactive neurogenic bladder
large bladders!
lesion in:
sensory afferents (from bladder) = sensory neurogenic bladder motor & visceral efferents (to bladder) = motor neurogenic bladder sacral spinal cord centers involved in bladder function = autonomous neurogenic bladder
Pontine Micturition Center - 3 functions
inhibits SNS outflow = internal sphincter relax
activates PNS outflow = detrusor contracts
inhibits somatic outflow = external sphincter relax
speak hoarsely
sounds hyper-nasal
difficulty swallowing
lesion in CN 10 /vagus nerve
Central Auditory Pathways
Ipsilateral
cochlea (inner ear)
cochlear portion of vestibulocochlear nerve CN8
cochlear nuclei (medulla)
Bilateral superior olive nucleus (pons) lateral lemniscus inferior colliculus (midbrain) medial geniculate (thalamus) primary auditory cortex (transverse temporal gyri on superior aspect of superior temporal gyrus)
Very loud sounds are heard as “too loud”
lesion of trigeminal (5) or facial nerve (7)
(leads to loss of dampening of very loud
sounds in the middle ear)
Hyperacusis
cannot wrinkle forehead
LMN lesion
facial nerve/CN7
Vestibulopathy - lesion location
Lesion in labyrinth, nerve or nucleus
3 meds cause seizures in normal people
tramadol (weak mu agonist & SNRI)
buproprion
clozapine (1st gen antipsychotic)
(TBC-to b continued)
bladder - Sympathetic innervation
T10- L2 ventral roots HYPOGASTRIC nerve Innervate detrusor muscle via beta receptors= Bladder relaxes and fills Internal sphincter contracts (can't pee)
bladder - parasympathetic innervation
S2-S4 ventral roots
PELVIC nerves
Innervate detrusor muscle via M Ach receptors=
bladder contracts & empties (pee)
pupil light reflex
Light in one eye- both get smaller
Ipsilateral optic nerve in
Bilateral ocularmotor nerve out
jaw jerk reflex
Partly open jaw - masseter and temporalis contract
V3 in (mandibular nerve) V1 motor out (ophthalmic nerve)
Corneal reflex
Gently touch cornea- both eyes blink
Ipsilateral V1 in (ophthalmic nerve)
Bilateral motor facial nerve out
Gag reflex
Gently touch posterior pharynx on one side-Bilateral soft palate goes up, Bilateral posterior pharynx comes in
Ipsilateral glosso-pharangeal nerve in
Bilateral vagus nerve out
motion sickness - tx
scopolamine
diphenhydramine