Neuro Flashcards

0
Q

Decreased number of receptor sites available

A

Myasthenia Gravis

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1
Q

Death 2-6 years after diagnosis

A

ALS

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2
Q

80% recover

A

Guillian Barre syndrome

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3
Q

Riluzole

A

ALS

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4
Q

Brain scan used to rule out MS

A

Guillian Barre syndrome

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5
Q

Thymus gland may be enlarged

A

Myasthenia Gravis

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6
Q

When does Guillian Barre syndrome usually peak

A

14 days usually

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7
Q

What is areflexia

A

Lack of reflexes

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8
Q

MRI shows brain plaque

A

Multiple sclerosis

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9
Q

Affects myelin sheath

A

Guillian Barre syndrome and multiple sclerosis

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10
Q

Lou Gehrig’s disease

A

ALS

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11
Q

Genetically transmitted autosomal dominant

A

Huntingtons disease

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12
Q

Tensilon test

A

Myasthenia Gravis

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13
Q

Leaves mind completely unaffected

A

ALS

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14
Q

Uncontrollable urge to move legs

A

Restless leg syndrome

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15
Q

Preceded by acute viral infection

A

Guillian Barre syndrome

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16
Q

Limb wasting

A

ALS

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17
Q

Symmetrical onset in lower extremities

A

Guillian Barre syndrome

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18
Q

Plasmapheresis

A

Myasthenia Gravis and Guillian Barre syndrome

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19
Q

Moving relives symptoms

A

Restless leg syndrome

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20
Q

High caloric diet usually needed

A

Huntingtons disease

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21
Q

Affects twice as many men

A

ALS

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22
Q

Immune cells attack myelin sheath

A

Guillian barre syndrome and multiple sclerosis

23
Q

Progressive degenerative brain disorder

A

Huntingtons disease

24
Facial expressions are difficult
Myasthenia Gravis and huntingtons disease
25
Gliosis (scarring) of myelin sheath
Multiple sclerosis
26
Symptoms tend to occur when person is resting
Restless leg syndrome
27
Progressive degenerative CNS disorder
Myasthenia Gravis
28
Dysfunction of brains basal ganglia circuits that use neurotransmitter dopamine
Restless leg syndrome
29
Medications to treat chorea
Huntingtons disease
30
Death usually within 2-3 years after onset of symptoms
ALS
31
Demyelinization
Guillian barre syndrome and multiple sclerosis
32
CSF with high amount of protein
Guillian Barre syndrome
33
Very rapid onset
Guillian barre syndrome
34
Acute demyelating polyneuropathy
Guillian barre syndrome
35
More prevalent in temperate climates
Multiple sclerosis
36
The course is chronic inflammation, demyelination, gliosis
Multiple sclerosis
37
Elevated CPK
ALS
38
Immunomoduators
Multiple sclerosis
39
What is the Tensilon Test?
Used in Myasthenia Gravis patients to show improved muscle contractility
40
How do you do the Tensilon Test?
Edrophonium chloride, 2-10 mg, is injected IV. Thirty seconds later, facial muscle weakness and ptosis should resolve for about 5 minutes. This immediate improvement usually confirms the diagnosis. Keep atropine 0.4 mg ready to control the side effects of edrophonium (convulsions and restlessness)
41
What are you trying to do with plasmapheresis?
Reduce circulating antibodies
42
What is the technique used to treat exacerbations by a temporary reduction in the titer of circulating antibodies?
Plasma exchange (plasmapheresis) used is myasthenia Gravis patients for management
43
What is a thymectomy
Surgical removal of the thymus gland
44
What is special about cognitive function in ALS patient?
Patient remains cognitively intact!
45
What can you do for ALS?
No cure! But Riluzole can be used to slow progression of ALS
46
What is Riluzole? How does it work?
Used to slow progression of ALS. Blocks sodium channels in damaged nerves and decreases glutamate in brain
47
What percentage will recover from Guillian barre syndrome?
80%
48
Why is MRI used in Guillian Barre Syndrome?
MRI is used to see if there is plaque in brain. If there is not, it is probably Guillian. If there is, it is probably multiple sclerosis
49
What is important about diet in a patient with Huntingtons disease
High caloric requirements: 4,000-5,000 calories per day due to choreic movements
50
What is paresthesias
Abnormal sensations
51
What is dysesthesias
Unpleasant abnormal sensations
52
What is gliosis
Scarring
53
What is a very indicative sign of multiple sclerosis
MRI of brain and spinal cord shows plaques
54
What should be avoided with a MS patient who has constipation
Laxatives and enemas because they lead to dependance